Reena Ghildyal

Professor

Accepting PhD Students

1990 …2019

Research output per year

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Personal profile

Biography

Reena Ghildyal obtained her PhD in Life Science from Jawaharlal Nehru University, New Delhi, India; a premier Indian research university. This was followed by postdoctoral fellowships at the State Department of Agriculture, and Macfarlane Burnet Institute in Melbourne, Australia. 

In 2004 Reena was invited to establish a respiratory virology research group as part of a new Chinese Government initiative within Fudan University, Shanghai. On her return to Australia in 2007, she has continued her association with Fudan University and has been instrumental in establishing several bilateral research collaborations between Chinese and Australian scientists.

Reena moved to University of Canberra in 2010 where she is currently Professor in Microbiology and Director, Centre for Research in Therapeutic Solutions.

The focus of Reena's research is molecular pathogenesis of respiratory viruses with special reference to asthma exacerbations. Current projects include the validation of respiratory syncytial virus (RSV) vaccine candidates in vitro and in vivo; elucidating the role of cytoskeleton in RSV assembly, investigating the role of rhinovirus (HRV) proteases in disease.

Reena collaborates with research groups within Australia (Monash University, University of Queensland) and Internationally (University of South Florida, University of Georgia, Imperial College, Fudan University) and her research is funded by National Health and Medical Research Council, Australia-China Science Research Fund and Australia-India Science and Technology Research Fund.

Research interests

  • Molecular pathogenesis of respiratory viruses
  • Molecular basis of asthma
  • Respiratory virus assembly

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Projects

Research Output

Open Access
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  • 8 Citations (Scopus)
    1 Downloads (Pure)

    Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

    Hu, M., Schulze, K. E., Ghildyal, R., Henstridge, D. C., Kolanowski, J. L., New, E. J., Hong, Y., Hsu, A. C., Hansbro, P. M., Wark, P. A., Bogoyevitch, M. A. & Jans, D. A., 27 Jun 2019, In : eLife. 8, p. 1-30 30 p., 42448.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 2 Citations (Scopus)
    3 Downloads (Pure)

    Transcriptomic changes during TGF-beta-mediated differentiation of airway fibroblasts to myofibroblasts

    Walker, E. J., Heydet, D., Veldre, T. & Ghildyal, R., 30 Dec 2019, In : Scientific Reports. 9, 1, p. 20377 20377.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)

    Verdinexor (KPT-335), a Selective Inhibitor of Nuclear Export, Reduces Respiratory Syncytial Virus Replication In Vitro

    Jorquera, P. A., Mathew, C., Pickens, J., Williams, C., Luczo, J. M., Tamir, S., Ghildyal, R. & Tripp, R. A., 1 Feb 2019, In : Journal of Virology. 93, 4, p. 1-17 17 p., e0168418.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Citation (Scopus)

    Human Rhinovirus 3C protease cleaves RIPK1, concurrent with caspase 8 activation

    Croft, S. N., Walker, E. J. & Ghildyal, R., 1 Dec 2018, In : Scientific Reports. 8, 1, p. 1-11 11 p., 1569.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 6 Citations (Scopus)
    9 Downloads (Pure)