Projects per year
Reena Ghildyal obtained her PhD in Life Science from Jawaharlal Nehru University, New Delhi, India; a premier Indian research university. This was followed by postdoctoral fellowships at the State Department of Agriculture, and Macfarlane Burnet Institute in Melbourne, Australia.
In 2004 Reena was invited to establish a respiratory virology research group as part of a new Chinese Government initiative within Fudan University, Shanghai. On her return to Australia in 2007, she has continued her association with Fudan University and has been instrumental in establishing several bilateral research collaborations between Chinese and Australian scientists.
Reena moved to University of Canberra in 2010 where she is currently Professor in Microbiology and Director, Centre for Research in Therapeutic Solutions.
The focus of Reena's research is molecular pathogenesis of respiratory viruses with special reference to asthma exacerbations. Current projects include the validation of respiratory syncytial virus (RSV) vaccine candidates in vitro and in vivo; elucidating the role of cytoskeleton in RSV assembly, investigating the role of rhinovirus (HRV) proteases in disease.
Reena collaborates with research groups within Australia (Monash University, University of Queensland) and Internationally (University of South Florida, University of Georgia, Imperial College, Fudan University) and her research is funded by National Health and Medical Research Council, Australia-China Science Research Fund and Australia-India Science and Technology Research Fund.
- Molecular pathogenesis of respiratory viruses
- Molecular basis of asthma
- Respiratory virus assembly
1/03/18 → 1/01/19
Ghildyal, R. & Mathew, C.
3/10/16 → 27/09/19
24/07/15 → 30/06/17
MTA between UC and University of South Florida in relation to Recombinant RSV encoding mutations in the matrix (M) gene
25/11/14 → 25/11/17
Respiratory Syncytial Virus Matrix Protein-Host Protein Interactions as targets for Therapeutics -via by Monash University
Ghildyal, R., Bardin, P. & Tripp, R.
1/01/13 → 31/12/15
Lauric acid ameliorates lipopolysaccharide (LPS)-induced liver inflammation by mediating TLR4/MyD88 pathway in Sprague Dawley (SD) ratsKhan, H. U., Aamir, K., Jusuf, P. R., Sethi, G., Sisinthy, S. P., Ghildyal, R. & Arya, A., 15 Jan 2021, In: Life Sciences. 265, p. 1-17 17 p., 118750.
Research output: Contribution to journal › Article › peer-review
Endoplasmic reticulum stress activates unfolded protein response signaling and mediates inflammation, obesity, and cardiac dysfunction: Therapeutic and molecular approachAmen, O. M., Sarker, S. D., Ghildyal, R. & Arya, A., Sep 2019, In: Frontiers in Pharmacology. 10, p. 977 21 p., 977.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile28 Citations (Scopus)7 Downloads (Pure)
Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus productionHu, M., Schulze, K. E., Ghildyal, R., Henstridge, D. C., Kolanowski, J. L., New, E. J., Hong, Y., Hsu, A. C., Hansbro, P. M., Wark, P. A., Bogoyevitch, M. A. & Jans, D. A., 27 Jun 2019, In: eLife. 8, p. 1-30 30 p., 42448.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile9 Citations (Scopus)4 Downloads (Pure)
Transcriptomic changes during TGF-beta-mediated differentiation of airway fibroblasts to myofibroblastsWalker, E. J., Heydet, D., Veldre, T. & Ghildyal, R., 30 Dec 2019, In: Scientific Reports. 9, 1, p. 20377 20377.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile9 Citations (Scopus)2 Downloads (Pure)
Verdinexor (KPT-335), a Selective Inhibitor of Nuclear Export, Reduces Respiratory Syncytial Virus Replication In VitroJorquera, P. A., Mathew, C., Pickens, J., Williams, C., Luczo, J. M., Tamir, S., Ghildyal, R. & Tripp, R. A., 1 Feb 2019, In: Journal of Virology. 93, 4, p. 1-17 17 p., e0168418.
Research output: Contribution to journal › Article › peer-reviewOpen Access