Reena GHILDYAL

Available to supervise Higher Degree by Research students

1990 …2019
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Personal profile

Biography

Reena Ghildyal obtained her PhD in Life Science from Jawaharlal Nehru University, New Delhi, India; a premier Indian research university. This was followed by postdoctoral fellowships at the State Department of Agriculture, and Macfarlane Burnet Institute in Melbourne, Australia. 

In 2004 Reena was invited to establish a respiratory virology research group as part of a new Chinese Government initiative within Fudan University, Shanghai. On her return to Australia in 2007, she has continued her association with Fudan University and has been instrumental in establishing several bilateral research collaborations between Chinese and Australian scientists.

Reena moved to University of Canberra in 2010 where she is currently Professor in Microbiology and Director, Centre for Research in Therapeutic Solutions.

The focus of Reena's research is molecular pathogenesis of respiratory viruses with special reference to asthma exacerbations. Current projects include the validation of respiratory syncytial virus (RSV) vaccine candidates in vitro and in vivo; elucidating the role of cytoskeleton in RSV assembly, investigating the role of rhinovirus (HRV) proteases in disease.

Reena collaborates with research groups within Australia (Monash University, University of Queensland) and Internationally (University of South Florida, University of Georgia, Imperial College, Fudan University) and her research is funded by National Health and Medical Research Council, Australia-China Science Research Fund and Australia-India Science and Technology Research Fund.

Research interests

  • Molecular pathogenesis of respiratory viruses
  • Molecular basis of asthma
  • Respiratory virus assembly

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Projects 2010 2019

Research Output 1990 2018

Human Rhinovirus 3C protease cleaves RIPK1, concurrent with caspase 8 activation

Croft, S. N., Walker, E. J. & Ghildyal, R. 25 Jan 2018 In : Scientific Reports. 8, 1, 11 p., 1569

Research output: Contribution to journalArticle

Receptor-Interacting Protein Serine-Threonine Kinases
Caspase 8
Rhinovirus
Protein Kinases
Apoptosis
2 Citations

Molecular changes during TGFβ-mediated lung fibroblast-myofibroblast differentiation: implication for glucocorticoid resistance

Breton, J-D., Heydet, D., Starrs, L., Veldre, T. & Ghildyal, R. 13 Apr 2018 In : Physiological Reports. 6, 7, 12 p., e13669

Research output: Contribution to journalArticle

Open Access
File
Myofibroblasts
Airway Remodeling
Fibroblasts
Lung
Glucocorticoid Receptors
2 Citations

Molecular Requirements for Self-Interaction of the Respiratory Syncytial Virus Matrix Protein in Living Mammalian Cells

Trevisan, M., Di Antonio, V., Radeghieri, A., Palù, G., Ghildyal, R. & Alvisi, G. 3 Mar 2018 In : Viruses. 10, 3, p. 109-1 - 109-13 13 p., 109

Research output: Contribution to journalArticle

Open Access
File
Respiratory Syncytial Viruses
Proteins
Bronchiolitis
Energy Transfer
Protein C

Nuclear transport in Entamoeba histolytica: knowledge gap and therapeutic potential

Gwairgi, M. A. & Ghildyal, R. 22 Mar 2018 In : Parasitology. 145, 11, p. 1378 – 1387 10 p.

Research output: Contribution to journalArticle

Entamoeba histolytica
Cell Nucleus Active Transport
phagocytosis
therapeutics
Protozoa

Respiratory Syncytial Virus Matrix (M) Protein Interacts with Actin In Vitro and in Cell Culture

SHAHRIARI, S., Wei, K-J. & Ghildyal, R. 30 Sep 2018 In : Viruses. 10, 10, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
File
Respiratory Syncytial Viruses
Actins
Actin Cytoskeleton
Cell Culture Techniques
Cytochalasin D