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Biography
Dr Shadi Shahriari is a Lecturer in Physiology and virology at the School of Science, University of Canberra. She completed her Ph.D at the University of Canberra under the supervision of Professor Reena Ghildyal, which she was awarded on September 23, 2021, for her thesis on the "Respiratory Syncytial Virus Matrix Protein Interactions with the Host Actin Cytoskeleton in Viral Assembly and Budding."
Shadi's primary research focuses on the molecular pathogenesis of respiratory viruses, particularly Respiratory Syncytial Virus (RSV). Her work investigates how viruses interact with the host cell's cytoskeleton—the internal scaffolding that gives a cell its shape. She has found an interaction between the RSV matrix protein and the host cell cytoskeleton, which is crucial for the virus's assembly and budding. This research has the potential to provide a foundation for developing antiviral drugs for RSV infections, which are a major cause of hospitalization in young children. Dr Shahriari has also published research on rhinovirus and its connection to the development of asthma. Her work is conducted within the Biomedical Science Research Group at the University of Canberra's Faculty of Science and Technology.
Education/Academic qualification
PhD, Respiratory Syncytial Virus Matrix Protein Interactions with the Host Actin Cytoskeleton in Viral Assembly and Budding
Award Date: 23 Sept 2021
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Re-purposing a cancer therapeutic in combination with a non-steroidal inflammatory drug for the treatment of Respiratory Syncytial Virus
SHAHRIARI, S. (CI)
1/03/23 → 31/05/25
Project: Research
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Editorial: Viral interactions with the nucleus, volume II
Ciccarese, F., Zhang, X., Shahriari, S. & Ghildyal, R., 2024, In: Frontiers in Microbiology. 15, p. 1-2 2 p., 1419921.Research output: Contribution to journal › Editorial › peer-review
Open Access -
The actin-binding protein palladin associates with the respiratory syncytial virus matrix protein
Shahriari, S. & Ghildyal, R., Oct 2024, In: Journal of Virology. 98, 10, p. 1-23 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)26 Downloads (Pure) -
Rhinovirus protease cleavage of nucleoporins: perspective on implications for airway remodeling
Moorhouse, J., Val, N., Shahriari, S., Nelson, M., Ashby, R. & Ghildyal, R., 2023, In: Frontiers in Microbiology. 14, p. 1-7 7 p., 1321531.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Downloads (Pure) -
Respiratory Syncytial Virus Matrix (M) Protein Interacts with Actin In Vitro and in Cell Culture
SHAHRIARI, S., Wei, K.-J. & Ghildyal, R., 30 Sept 2018, In: Viruses. 10, 10, p. 1-12 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Citations (Scopus)83 Downloads (Pure) -
Host cytoskeleton in respiratory syncytial virus assembly and budding
SHAHRIARI, S., Gordon, J. & GHILDYAL, R., 26 Sept 2016, In: Virology Journal. 13, 1, p. 1-11 11 p., 161.Research output: Contribution to journal › Review article › peer-review
Open AccessFile36 Citations (Scopus)72 Downloads (Pure)