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Personal profile

Biography

Dr Sudha Rao obtained her BSC (Hons.) degree at Keele University, UK. She subsequently joined Aventis and as a Senior Scientist was involved in developing therapeutics strategies in the arena of asthma & COPD.

Sudha received a prestigious Aventis Fellowship and obtained her PhD from the University of London, Kings College in 2000. During this period, she joined a team of scientists at Aventis Pharma to establish the first therapeutic microarray screening platform in the UK in collaboration with Affymetrix, USA.

Sudha was recruited by Professor Shannon (Gene Expression and Epigenomics Group) as a postdoctoral fellow to JCSMR, ANU in 2000. In 2003 she was appointed as a research fellow (Level B) and in 2009, Sudha was appointed Team Leader of the Immune Regulation & Nuclear Dynamics Group at JCSMR, ANU.

Sudha moved to the University of Canberra in 2010 as an Associate Professor in Molecular & Cellular Biology and is also on the staff of the Centre for Research in Therapeutic Solutions (CResTS).

Sudha has extensive experience in transcriptional biology and genomic technologies that spans both pharmaceutical and academic settings. The primary focus of Sudha's research group has been to unravel complex epigenetic-signatures in transcription programs in the context of the immune system, as well as to understand the deregulatory mechanisms operating in cancer settings.

Research interests

  • Epigenetic regulation
  • Breast cancer and cancer stem cells
  • Memory T cells

 

Fingerprint Dive into the research topics where Sudha Rao is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Genes Medicine & Life Sciences
Protein Kinase C Medicine & Life Sciences
Epithelial-Mesenchymal Transition Medicine & Life Sciences
Neoplastic Stem Cells Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences

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Projects 2011 2020

Research Output 2005 2019

1 Citation (Scopus)

Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer

Wu, F., McCuaig, R. D., Sutton, C. R., Tan, A. H. Y., Jeelall, Y., Bean, E. G., Dai, J., Prasanna, T., Batham, J., Malik, L., Yip, D., Dahlstrom, J. E. & Rao, S., Jun 2019, In : International Journal of Molecular Sciences. 20, 12, p. 1-13 13 p., 3080.

Research output: Contribution to journalArticle

Open Access
File
Triple Negative Breast Neoplasms
Circulating Neoplastic Cells
metastasis
breast
brain

SETDB-1: A potential epigenetic regulator in breast cancer metastasis

Batham, J., Lim, P. S. & Rao, S., 9 Aug 2019, In : Cancers. 11, 8, p. 1-20 20 p., 1143.

Research output: Contribution to journalReview article

Open Access
File
Histone-Lysine N-Methyltransferase
Epigenomics
Breast Neoplasms
Neoplasm Metastasis
Stem Cells
9 Citations (Scopus)
5 Downloads (Pure)

Optimizing poly (ADP-ribose) polymerase inhibition through combined epigenetic and immunotherapy

PRASANNA, T., Wu, F., Khanna, K. K., Yip, D., Malik, L., Dahlstrom, J. E. & Rao, S., 1 Nov 2018, In : Cancer Science. 109, 11, p. 3383-3392 10 p.

Research output: Contribution to journalReview article

Open Access
File
Poly(ADP-ribose) Polymerases
Epigenomics
Immunotherapy
CD274 Antigen
Cell Death
56 Citations (Scopus)

Epigenetics and immunotherapy: The current state of play

Dunn, J. & Rao, S., 1 Jul 2017, In : Molecular Immunology. 87, p. 227-239 13 p.

Research output: Contribution to journalArticle

Open Access
File
Epigenomics
Immunotherapy
Neoplasms
Tumor Microenvironment
Tumor Escape
10 Citations (Scopus)

Regulation of H3K4me3 at Transcriptional Enhancers Characterizes Acquisition of Virus-Specific CD8+ T Cell-Lineage-Specific Function

Russ, B. E., Olshansky, M., Li, J., Nguyen, M. L. T., Gearing, L. J., Nguyen, T. H. O., Olson, M. R., McQuilton, H. A., Nüssing, S., Khoury, G., Purcell, D. F. J., Hertzog, P. J., Rao, S. & Turner, S. J., 19 Dec 2017, In : Cell Reports. 21, 12, p. 3624-3636 13 p.

Research output: Contribution to journalArticle

Open Access
File
T-cells
Cell Lineage
Viruses
T-Lymphocytes
Cell Differentiation