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Personal profile

Biography

Dr Sudha Rao obtained her BSC (Hons.) degree at Keele University, UK. She subsequently joined Aventis and as a Senior Scientist was involved in developing therapeutics strategies in the arena of asthma & COPD.

Sudha received a prestigious Aventis Fellowship and obtained her PhD from the University of London, Kings College in 2000. During this period, she joined a team of scientists at Aventis Pharma to establish the first therapeutic microarray screening platform in the UK in collaboration with Affymetrix, USA.

Sudha was recruited by Professor Shannon (Gene Expression and Epigenomics Group) as a postdoctoral fellow to JCSMR, ANU in 2000. In 2003 she was appointed as a research fellow (Level B) and in 2009, Sudha was appointed Team Leader of the Immune Regulation & Nuclear Dynamics Group at JCSMR, ANU.

Sudha moved to the University of Canberra in 2010 as an Associate Professor in Molecular & Cellular Biology and is also on the staff of the Centre for Research in Therapeutic Solutions (CResTS).

Sudha has extensive experience in transcriptional biology and genomic technologies that spans both pharmaceutical and academic settings. The primary focus of Sudha's research group has been to unravel complex epigenetic-signatures in transcription programs in the context of the immune system, as well as to understand the deregulatory mechanisms operating in cancer settings.

Research interests

  • Epigenetic regulation
  • Breast cancer and cancer stem cells
  • Memory T cells

 

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Projects 2011 2020

Research Output 2005 2018

6 Citations (Scopus)

Optimizing poly (ADP-ribose) polymerase inhibition through combined epigenetic and immunotherapy

PRASANNA, T., Wu, F., Khanna, K. K., Yip, D., Malik, L., Dahlstrom, J. E. & Rao, S., 1 Nov 2018, In : Cancer Science. 109, 11, p. 3383-3392 10 p.

Research output: Contribution to journalReview article

Open Access
File
Poly(ADP-ribose) Polymerases
Epigenomics
Immunotherapy
CD274 Antigen
Cell Death
47 Citations (Scopus)

Epigenetics and immunotherapy: The current state of play

Dunn, J. & Rao, S., 1 Jul 2017, In : Molecular Immunology. 87, p. 227-239 13 p.

Research output: Contribution to journalArticle

Epigenomics
Immunotherapy
Neoplasms
Tumor Microenvironment
Tumor Escape
7 Citations (Scopus)

Regulation of H3K4me3 at Transcriptional Enhancers Characterizes Acquisition of Virus-Specific CD8+ T Cell-Lineage-Specific Function

Russ, B. E., Olshansky, M., Li, J., Nguyen, M. L. T., Gearing, L. J., Nguyen, T. H. O., Olson, M. R., McQuilton, H. A., Nüssing, S., Khoury, G., Purcell, D. F. J., Hertzog, P. J., Rao, S. & Turner, S. J., 19 Dec 2017, In : Cell Reports. 21, 12, p. 3624-3636 13 p.

Research output: Contribution to journalArticle

T-cells
Cell Lineage
Viruses
T-Lymphocytes
Cell Differentiation
Open Access
File
Immune System
Phosphotransferases
Neoplasms
Gene Expression Regulation
Epigenomics
10 Citations (Scopus)

The biological and clinical significance of stromal-epithelial interactions in breast cancer

Wu, F., DUNN, J., RAO, S. & Dahlstrom, J., 2017, In : Pathology. 49, 2, p. 133-140 8 p.

Research output: Contribution to journalArticle

Open Access
File
Tumor Microenvironment
Breast Neoplasms
Neoplasms
Cellular Microenvironment
Epigenomics