RNAi therapeutic intervention of human viral respiratory disease

  • MAHALINGAM, Surendran, (CI)
  • Spann, Kirsten (CoI)
  • Tripp, Ralph (CoI)

    Project: Other

    Description

    Human metapneumovirus (HMPV), causes clinical disease that is very similar to human respiratory syncytial virus (RSV) and co-circulates with RSV. HMPV is emerging as a major cause of morbidity and life-threatening respiratory tract disease in infants, young children and the elderly worldwide. No treatment is currently available. The objectives of this proposal are to develop novel antiviral drugs that silence the expression of viral genes and to examine protection in an animal model of disease.
    Short titleRNAi therapeutic intervention of human viral respi
    StatusFinished
    Effective start/end date1/01/0831/12/10