The incidence of human and animal diseases caused by mosquito borne viruses has increased at an alarming rate globally. The project aims to utilize state-of-the-art reverse genetics technology to address the mechanisms regulating the virulence/fitness of the virus during transition from the mosquito vector to mammalian host. This project is significant, as it will: 1) provide information that is essential for understanding the mechanisms of viral-host adaptations; 2) assist in the design of strategies for the control, treatment and eradication of these viruses; and 3) help predict their emergence. The knowledge gained from this research will be of immense benefit to the community worldwide.
|Short title||The biology of arbovirus virulence and fitness in|
|Effective start/end date||21/09/07 → 21/09/10|