A comparison of laser Doppler fluxmetry and transcutaneous oxygen pressure measurement in the dysvascular patient requiring amputation

M Mars, A McKune, J V Robbs

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

OBJECTIVE: To determine the predictive power of laser Doppler fluxmetry (LDF), both heated and unheated, as a preoperative investigation of wound healing potential in dysvascular patients requiring amputation, by comparison with transcutaneous oxygen pressure measurement (TcpO2) and the limb to chest TcpO2 index.

METHODS: Thirty-five non-diabetic patients with peripheral vascular disease were investigated before amputation. Heated and unheated LDF and heated TcpO2 measurements were taken on the chest wall and at the routine above-knee, below-knee and mid-foot amputation levels. Wound healing potential was evaluated against a TcpO2 index value of 0.55 and on clinical outcome.

RESULTS: A heated LDF value of 4.9 arbitrary units (au) was shown by receiver-operator characteristic curve to have the best predictive power, with an overall accuracy for preoperative prediction of wound healing of 91.4%, and a predictive value for wound failure of 89%. Based on the heated LDF of 4.9 au, review of 26 amputations performed shows the overall accuracy for preoperative prediction of wound healing of 92.3%, a predictive value for wound healing of 100%, and a predictive value for wound failure of 62.5%.

CONCLUSION: A heated LDF value of 4.9 au appears to be a useful predictor of the potential of an amputation site to heal.

Original languageEnglish
Pages (from-to)53-8
Number of pages6
JournalEuropean Journal of Vascular and Endovascular Surgery
Volume16
Issue number1
Publication statusPublished - Jul 1998

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Amputation
Wound Healing
Lasers
Oxygen
Pressure
Knee
Peripheral Vascular Diseases
Wounds and Injuries
Thoracic Wall
Foot
Thorax
Extremities

Cite this

@article{7e5ff1e011f346b79d722531640f2ddb,
title = "A comparison of laser Doppler fluxmetry and transcutaneous oxygen pressure measurement in the dysvascular patient requiring amputation",
abstract = "OBJECTIVE: To determine the predictive power of laser Doppler fluxmetry (LDF), both heated and unheated, as a preoperative investigation of wound healing potential in dysvascular patients requiring amputation, by comparison with transcutaneous oxygen pressure measurement (TcpO2) and the limb to chest TcpO2 index.METHODS: Thirty-five non-diabetic patients with peripheral vascular disease were investigated before amputation. Heated and unheated LDF and heated TcpO2 measurements were taken on the chest wall and at the routine above-knee, below-knee and mid-foot amputation levels. Wound healing potential was evaluated against a TcpO2 index value of 0.55 and on clinical outcome.RESULTS: A heated LDF value of 4.9 arbitrary units (au) was shown by receiver-operator characteristic curve to have the best predictive power, with an overall accuracy for preoperative prediction of wound healing of 91.4{\%}, and a predictive value for wound failure of 89{\%}. Based on the heated LDF of 4.9 au, review of 26 amputations performed shows the overall accuracy for preoperative prediction of wound healing of 92.3{\%}, a predictive value for wound healing of 100{\%}, and a predictive value for wound failure of 62.5{\%}.CONCLUSION: A heated LDF value of 4.9 au appears to be a useful predictor of the potential of an amputation site to heal.",
keywords = "Amputation, Amputation Stumps, Blood Gas Monitoring, Transcutaneous, Data Interpretation, Statistical, Hot Temperature, Humans, Laser-Doppler Flowmetry, Leg, Peripheral Vascular Diseases, Predictive Value of Tests, Wound Healing, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't",
author = "M Mars and A McKune and Robbs, {J V}",
year = "1998",
month = "7",
language = "English",
volume = "16",
pages = "53--8",
journal = "European Journal of Vascular Surgery",
issn = "1078-5884",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - A comparison of laser Doppler fluxmetry and transcutaneous oxygen pressure measurement in the dysvascular patient requiring amputation

AU - Mars, M

AU - McKune, A

AU - Robbs, J V

PY - 1998/7

Y1 - 1998/7

N2 - OBJECTIVE: To determine the predictive power of laser Doppler fluxmetry (LDF), both heated and unheated, as a preoperative investigation of wound healing potential in dysvascular patients requiring amputation, by comparison with transcutaneous oxygen pressure measurement (TcpO2) and the limb to chest TcpO2 index.METHODS: Thirty-five non-diabetic patients with peripheral vascular disease were investigated before amputation. Heated and unheated LDF and heated TcpO2 measurements were taken on the chest wall and at the routine above-knee, below-knee and mid-foot amputation levels. Wound healing potential was evaluated against a TcpO2 index value of 0.55 and on clinical outcome.RESULTS: A heated LDF value of 4.9 arbitrary units (au) was shown by receiver-operator characteristic curve to have the best predictive power, with an overall accuracy for preoperative prediction of wound healing of 91.4%, and a predictive value for wound failure of 89%. Based on the heated LDF of 4.9 au, review of 26 amputations performed shows the overall accuracy for preoperative prediction of wound healing of 92.3%, a predictive value for wound healing of 100%, and a predictive value for wound failure of 62.5%.CONCLUSION: A heated LDF value of 4.9 au appears to be a useful predictor of the potential of an amputation site to heal.

AB - OBJECTIVE: To determine the predictive power of laser Doppler fluxmetry (LDF), both heated and unheated, as a preoperative investigation of wound healing potential in dysvascular patients requiring amputation, by comparison with transcutaneous oxygen pressure measurement (TcpO2) and the limb to chest TcpO2 index.METHODS: Thirty-five non-diabetic patients with peripheral vascular disease were investigated before amputation. Heated and unheated LDF and heated TcpO2 measurements were taken on the chest wall and at the routine above-knee, below-knee and mid-foot amputation levels. Wound healing potential was evaluated against a TcpO2 index value of 0.55 and on clinical outcome.RESULTS: A heated LDF value of 4.9 arbitrary units (au) was shown by receiver-operator characteristic curve to have the best predictive power, with an overall accuracy for preoperative prediction of wound healing of 91.4%, and a predictive value for wound failure of 89%. Based on the heated LDF of 4.9 au, review of 26 amputations performed shows the overall accuracy for preoperative prediction of wound healing of 92.3%, a predictive value for wound healing of 100%, and a predictive value for wound failure of 62.5%.CONCLUSION: A heated LDF value of 4.9 au appears to be a useful predictor of the potential of an amputation site to heal.

KW - Amputation

KW - Amputation Stumps

KW - Blood Gas Monitoring, Transcutaneous

KW - Data Interpretation, Statistical

KW - Hot Temperature

KW - Humans

KW - Laser-Doppler Flowmetry

KW - Leg

KW - Peripheral Vascular Diseases

KW - Predictive Value of Tests

KW - Wound Healing

KW - Comparative Study

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

M3 - Article

VL - 16

SP - 53

EP - 58

JO - European Journal of Vascular Surgery

JF - European Journal of Vascular Surgery

SN - 1078-5884

IS - 1

ER -