A randomised controlled trial of consumption of dark chocolate in pregnancy to reduce pre-eclampsia: Difficulties in recruitment, allocation and adherence

Subashini Gnanendran, Jemma Porrett, Cindy Woods, Maryke Buttrose, Clare Jukka, Jane Hollins, Stephen Robson, Caroline de Costa

Research output: Contribution to journalOther Journal Articlepeer-review

1 Citation (Scopus)

Abstract

In 2013–2014 we undertook a randomised controlled trial (RCT) to determine whether the daily ingestion of dark chocolate during pregnancy could reduce the incidence of pre-eclampsia in primigravidae. However, after two years we had not succeeded in recruiting more than 3.5% of the number of participants required to answer the research question, and the trial was halted. We also reviewed the literature on this topic and found it to be limited. We report here our findings and discuss the difficulties facing researchers in this area.

Original languageEnglish
Pages (from-to)358-361
Number of pages4
JournalAustralian and New Zealand Journal of Obstetrics and Gynaecology
Volume58
Issue number3
DOIs
Publication statusPublished - Jun 2018
Externally publishedYes

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