A rapid decline in corneal small fibers and occurrence of foot ulceration and Charcot foot

Cirous Dehghani; Anthony W. Russell; Bruce A. Perkins; Rayaz A. Malik; Nicola Pritchard; Katie Edwards; Ayda M. Shahidi; Sangeetha Srinivasan; Nathan Efron

doi:10.1016/j.jdiacomp.2016.07.004

A rapid decline in corneal small fibers and occurrence of foot ulceration and Charcot foot

Cirous Dehghani, Anthony W. Russell, Bruce A. Perkins, Rayaz A. Malik, Nicola Pritchard, Katie Edwards, Ayda M. Shahidi, Sangeetha Srinivasan, Nathan Efron

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

We present clinical, neuropathy and corneal nerve morphology data in a participant with type 2 diabetes who developed diabetic foot ulceration, partial amputation and Charcot during a longitudinal observational study. While conventional measures of neuropathy did not deteriorate significantly, corneal nerve parameters showed a rapid reduction prior to the development of foot complications.

Original language	English
Pages (from-to)	1437-1439
Number of pages	3
Journal	Journal of Diabetes and Its Complications
Volume	30
Issue number	8
DOIs	https://doi.org/10.1016/j.jdiacomp.2016.07.004
Publication status	Published - 1 Nov 2016
Externally published	Yes

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title = "A rapid decline in corneal small fibers and occurrence of foot ulceration and Charcot foot",

abstract = "We present clinical, neuropathy and corneal nerve morphology data in a participant with type 2 diabetes who developed diabetic foot ulceration, partial amputation and Charcot during a longitudinal observational study. While conventional measures of neuropathy did not deteriorate significantly, corneal nerve parameters showed a rapid reduction prior to the development of foot complications.",

keywords = "Corneal confocal microscopy, Corneal nerve morphology, Diabetic foot complications, Diabetic peripheral neuropathy, Neuropathy measures",

author = "Cirous Dehghani and Russell, {Anthony W.} and Perkins, {Bruce A.} and Malik, {Rayaz A.} and Nicola Pritchard and Katie Edwards and Shahidi, {Ayda M.} and Sangeetha Srinivasan and Nathan Efron",

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T1 - A rapid decline in corneal small fibers and occurrence of foot ulceration and Charcot foot

AU - Dehghani, Cirous

AU - Russell, Anthony W.

AU - Perkins, Bruce A.

AU - Malik, Rayaz A.

AU - Pritchard, Nicola

AU - Edwards, Katie

AU - Shahidi, Ayda M.

AU - Srinivasan, Sangeetha

AU - Efron, Nathan

PY - 2016/11/1

Y1 - 2016/11/1

N2 - We present clinical, neuropathy and corneal nerve morphology data in a participant with type 2 diabetes who developed diabetic foot ulceration, partial amputation and Charcot during a longitudinal observational study. While conventional measures of neuropathy did not deteriorate significantly, corneal nerve parameters showed a rapid reduction prior to the development of foot complications.

AB - We present clinical, neuropathy and corneal nerve morphology data in a participant with type 2 diabetes who developed diabetic foot ulceration, partial amputation and Charcot during a longitudinal observational study. While conventional measures of neuropathy did not deteriorate significantly, corneal nerve parameters showed a rapid reduction prior to the development of foot complications.

KW - Corneal confocal microscopy

KW - Corneal nerve morphology

KW - Diabetic foot complications

KW - Diabetic peripheral neuropathy

KW - Neuropathy measures

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U2 - 10.1016/j.jdiacomp.2016.07.004

DO - 10.1016/j.jdiacomp.2016.07.004

M3 - Article

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AN - SCOPUS:84994231684

SN - 1056-8727

VL - 30

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EP - 1439

JO - Journal of Diabetes and Its Complications

JF - Journal of Diabetes and Its Complications

IS - 8

ER -

A rapid decline in corneal small fibers and occurrence of foot ulceration and Charcot foot

Abstract

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