Purpose: Sedation scales have the potential to facilitate effective procedural sedation and analgesia in the cardiac catheterization laboratory (CCL). For this potential to become realized, a scale that is suitable for use in the CCL either needs to be identified or developed. Design: A structured review strategy was applied. Methods: To identify sedation scales, a review of Medline and CINHAL was conducted. Findings: One sedation scale for the CCL, the North American Society for Pacing and Electrophysiology Sedation Scale, and 15 intensive care unit (ICU) scales met the inclusion and exclusion criteria. Analysis of the scale's item structures and psychometric properties was then performed. Conclusion: None of these scales were deemed suitable for use in the CCL. As such, further research is required to develop a new scale. The new scale should consist of more than one item to make it more effective for tracking the patient's response to medications. Specific tests required to conduct a rigorous evaluation of the new scale's psychometric properties are outlined in this article.