A Role for the Hippocampus in Card Sorting?

Rhiannon Corcoran, Dominic Upton

Research output: Contribution to journalArticlepeer-review

178 Citations (Scopus)


Abstract This study examines the performance of three groups of patients with epilepsy on three measures typically used to assess the integrity of the frontal lobes: the Modified Wisconsin Card Sorting Test (MWCST) verbal fluency and the Stroop test. The groups comprised sixteen patients with clearly defined hippocampal sclerosis thirteen patients with unilateral temporal lobe seizure onset and eighteen patients with unilateral frontal lobe onset. Results demonstrated that performance on the {MWCST} was most compromised by hippocampal sclerosis. These patients took longer to complete the task achieved fewer categories and made more perseverative errors than patients in the other groups. In contrast, verbal fluency and performance on the Stroop test were less affected by the presence of hippocampal scleroris. These results have both clinical and theoretical significance. It is argued that patients with hippocampal damage perform poorly on the {MWCST} because of the heavy working memory requirements of the test. Cautious use of this test as a tool to localise seizure origin in patients with complex partial seizures is therefore recommended. The findings are discussed in terms of Gray's (1982) model of the hippocampus as a comparator of actions.
Original languageEnglish
Pages (from-to)293-304
Number of pages12
Issue number2
Publication statusPublished - 1993


Dive into the research topics of 'A Role for the Hippocampus in Card Sorting?'. Together they form a unique fingerprint.

Cite this