Acclimation Training Improves Endurance Cycling Performance in the Heat without Inducing Endotoxemia

Joshua H. Guy, David B Pyne, Glen B. Deakin, Catherine M. Miller, Andrew M. Edwards

Research output: Contribution to journalArticle

12 Citations (Scopus)
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Abstract

PURPOSE: While the intention of endurance athletes undertaking short term heat training protocols is to rapidly gain meaningful physical adaption prior to competition in the heat, it is currently unclear whether or not this process also presents an overt, acute challenge to the immune system. The aim of this study was therefore to examine the effects of heat training on both endurance performance and biomarkers associated with inflammatory and immune system responses.

METHODS: Moderately-actively males (n = 24) were allocated randomly to either HOT (n = 8, 35°C, and 70% RH; NEUTRAL (n = 8, 20°C, and 45% RH); or a non-exercising control group, (CON, n = 8). Over the 18 day study HOT and NEUTRAL performed seven training sessions (40 min cycling at 55 of VO2 max) and all participants completed three heat stress tests (HST) at 35°C and 70% RH. The HST protocol comprised three × sub-maximal intervals followed by a 5 km time trial on a cycle ergometer. Serum samples were collected before and after each HST and analyzed for interleukin-6, immunoglobulin M and lipopolysaccharide.

RESULTS: Both HOT and NEUTRAL groups experienced substantial improvement to 5 km time trial performance (HOT -33 ± 20 s, p = 0.02, NEUTRAL -39 ± 18 s, p = 0.01) but only HOT were faster (-45 ± 25 s, and -12 s ± 7 s, p = 0.01) in HST3 compared to baseline and HST2. Interleukin-6 was elevated after exercise for all groups however there were no significant changes for immunoglobulin M or lipopolysaccharide.

CONCLUSIONS: Short-term heat training enhances 5 km cycling time trial performance in moderately-fit subjects by ~6%, similar in magnitude to exercise training in neutral conditions.Three top-up training sessions yielded a further 3% improvement in performance for the HOT group. Furthermore, the heat training did not pose a substantial challenge to the immune system.

Original languageEnglish
Article number318
Pages (from-to)318-327
Number of pages9
JournalFrontiers in Physiology
Volume7
Issue numberJUL
DOIs
Publication statusPublished - 2016
Externally publishedYes

Fingerprint

Endotoxemia
Acclimatization
Hot Temperature
Exercise Test
Immune System
Immunoglobulin M
Lipopolysaccharides
Interleukin-6
Athletes
Biomarkers
Exercise
Control Groups
Serum

Cite this

Guy, Joshua H. ; Pyne, David B ; Deakin, Glen B. ; Miller, Catherine M. ; Edwards, Andrew M. / Acclimation Training Improves Endurance Cycling Performance in the Heat without Inducing Endotoxemia. In: Frontiers in Physiology. 2016 ; Vol. 7, No. JUL. pp. 318-327.
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title = "Acclimation Training Improves Endurance Cycling Performance in the Heat without Inducing Endotoxemia",
abstract = "PURPOSE: While the intention of endurance athletes undertaking short term heat training protocols is to rapidly gain meaningful physical adaption prior to competition in the heat, it is currently unclear whether or not this process also presents an overt, acute challenge to the immune system. The aim of this study was therefore to examine the effects of heat training on both endurance performance and biomarkers associated with inflammatory and immune system responses.METHODS: Moderately-actively males (n = 24) were allocated randomly to either HOT (n = 8, 35°C, and 70{\%} RH; NEUTRAL (n = 8, 20°C, and 45{\%} RH); or a non-exercising control group, (CON, n = 8). Over the 18 day study HOT and NEUTRAL performed seven training sessions (40 min cycling at 55 of VO2 max) and all participants completed three heat stress tests (HST) at 35°C and 70{\%} RH. The HST protocol comprised three × sub-maximal intervals followed by a 5 km time trial on a cycle ergometer. Serum samples were collected before and after each HST and analyzed for interleukin-6, immunoglobulin M and lipopolysaccharide.RESULTS: Both HOT and NEUTRAL groups experienced substantial improvement to 5 km time trial performance (HOT -33 ± 20 s, p = 0.02, NEUTRAL -39 ± 18 s, p = 0.01) but only HOT were faster (-45 ± 25 s, and -12 s ± 7 s, p = 0.01) in HST3 compared to baseline and HST2. Interleukin-6 was elevated after exercise for all groups however there were no significant changes for immunoglobulin M or lipopolysaccharide.CONCLUSIONS: Short-term heat training enhances 5 km cycling time trial performance in moderately-fit subjects by ~6{\%}, similar in magnitude to exercise training in neutral conditions.Three top-up training sessions yielded a further 3{\%} improvement in performance for the HOT group. Furthermore, the heat training did not pose a substantial challenge to the immune system.",
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Acclimation Training Improves Endurance Cycling Performance in the Heat without Inducing Endotoxemia. / Guy, Joshua H.; Pyne, David B; Deakin, Glen B.; Miller, Catherine M.; Edwards, Andrew M.

In: Frontiers in Physiology, Vol. 7, No. JUL, 318, 2016, p. 318-327.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Acclimation Training Improves Endurance Cycling Performance in the Heat without Inducing Endotoxemia

AU - Guy, Joshua H.

AU - Pyne, David B

AU - Deakin, Glen B.

AU - Miller, Catherine M.

AU - Edwards, Andrew M.

PY - 2016

Y1 - 2016

N2 - PURPOSE: While the intention of endurance athletes undertaking short term heat training protocols is to rapidly gain meaningful physical adaption prior to competition in the heat, it is currently unclear whether or not this process also presents an overt, acute challenge to the immune system. The aim of this study was therefore to examine the effects of heat training on both endurance performance and biomarkers associated with inflammatory and immune system responses.METHODS: Moderately-actively males (n = 24) were allocated randomly to either HOT (n = 8, 35°C, and 70% RH; NEUTRAL (n = 8, 20°C, and 45% RH); or a non-exercising control group, (CON, n = 8). Over the 18 day study HOT and NEUTRAL performed seven training sessions (40 min cycling at 55 of VO2 max) and all participants completed three heat stress tests (HST) at 35°C and 70% RH. The HST protocol comprised three × sub-maximal intervals followed by a 5 km time trial on a cycle ergometer. Serum samples were collected before and after each HST and analyzed for interleukin-6, immunoglobulin M and lipopolysaccharide.RESULTS: Both HOT and NEUTRAL groups experienced substantial improvement to 5 km time trial performance (HOT -33 ± 20 s, p = 0.02, NEUTRAL -39 ± 18 s, p = 0.01) but only HOT were faster (-45 ± 25 s, and -12 s ± 7 s, p = 0.01) in HST3 compared to baseline and HST2. Interleukin-6 was elevated after exercise for all groups however there were no significant changes for immunoglobulin M or lipopolysaccharide.CONCLUSIONS: Short-term heat training enhances 5 km cycling time trial performance in moderately-fit subjects by ~6%, similar in magnitude to exercise training in neutral conditions.Three top-up training sessions yielded a further 3% improvement in performance for the HOT group. Furthermore, the heat training did not pose a substantial challenge to the immune system.

AB - PURPOSE: While the intention of endurance athletes undertaking short term heat training protocols is to rapidly gain meaningful physical adaption prior to competition in the heat, it is currently unclear whether or not this process also presents an overt, acute challenge to the immune system. The aim of this study was therefore to examine the effects of heat training on both endurance performance and biomarkers associated with inflammatory and immune system responses.METHODS: Moderately-actively males (n = 24) were allocated randomly to either HOT (n = 8, 35°C, and 70% RH; NEUTRAL (n = 8, 20°C, and 45% RH); or a non-exercising control group, (CON, n = 8). Over the 18 day study HOT and NEUTRAL performed seven training sessions (40 min cycling at 55 of VO2 max) and all participants completed three heat stress tests (HST) at 35°C and 70% RH. The HST protocol comprised three × sub-maximal intervals followed by a 5 km time trial on a cycle ergometer. Serum samples were collected before and after each HST and analyzed for interleukin-6, immunoglobulin M and lipopolysaccharide.RESULTS: Both HOT and NEUTRAL groups experienced substantial improvement to 5 km time trial performance (HOT -33 ± 20 s, p = 0.02, NEUTRAL -39 ± 18 s, p = 0.01) but only HOT were faster (-45 ± 25 s, and -12 s ± 7 s, p = 0.01) in HST3 compared to baseline and HST2. Interleukin-6 was elevated after exercise for all groups however there were no significant changes for immunoglobulin M or lipopolysaccharide.CONCLUSIONS: Short-term heat training enhances 5 km cycling time trial performance in moderately-fit subjects by ~6%, similar in magnitude to exercise training in neutral conditions.Three top-up training sessions yielded a further 3% improvement in performance for the HOT group. Furthermore, the heat training did not pose a substantial challenge to the immune system.

KW - Cycling

KW - Cytokine

KW - Endurance performance

KW - Heat acclimation

KW - Inflammation

KW - Lipopolysacharide

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DO - 10.3389/fphys.2016.00318

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JO - Frontiers in Physiology

JF - Frontiers in Physiology

SN - 1664-042X

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