Allele frequency data for 15 autosomal STR loci in eight Indonesian subpopulations

Runa Daniel, Stephen SARRE, Nurtami Soedarsono, Herawati Sudoyo, Helena Suryadi, Roland van Oorschot, Simon Walsh, Putut Widodo, Dennis MCNEVIN

    Research output: Contribution to journalArticle

    5 Citations (Scopus)

    Abstract

    Evolutionary and cultural history can affect the genetic characteristics of a population and influences the frequency of different variants at a particular genetic marker (allele frequency). These characteristics directly influence the strength of forensic DNA evidence and make the availability of suitable allele frequency information for every discrete country or jurisdiction highly relevant. Population substructure within Indonesia has not been well characterised but should be expected given the complex geographical, linguistic and cultural architecture of the Indonesian population. Here we use forensic short tandem repeat (STR) markers to identify a number of distinct genetic subpopulations within Indonesia and calculate appropriate population sub-structure correction factors. This data represents the most comprehensive investigation of population sub-structure within Indonesia to date using these markers. The results demonstrate that significant sub-structure is present within the Indonesian population and must be accounted for using island specific allele frequencies and corresponding substructure correction factors in the calculation of forensic DNA match statistics.
    Original languageEnglish
    Pages (from-to)45-52
    Number of pages8
    JournalForensic Science International: Genetics
    Volume20
    DOIs
    Publication statusPublished - 2016

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    Gene Frequency
    Indonesia
    Population
    Tandem Repeat Sequences
    DNA
    Population Characteristics
    Linguistics
    Genetic Markers
    Islands
    History

    Cite this

    Daniel, Runa ; SARRE, Stephen ; Soedarsono, Nurtami ; Sudoyo, Herawati ; Suryadi, Helena ; van Oorschot, Roland ; Walsh, Simon ; Widodo, Putut ; MCNEVIN, Dennis. / Allele frequency data for 15 autosomal STR loci in eight Indonesian subpopulations. In: Forensic Science International: Genetics. 2016 ; Vol. 20. pp. 45-52.
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    abstract = "Evolutionary and cultural history can affect the genetic characteristics of a population and influences the frequency of different variants at a particular genetic marker (allele frequency). These characteristics directly influence the strength of forensic DNA evidence and make the availability of suitable allele frequency information for every discrete country or jurisdiction highly relevant. Population substructure within Indonesia has not been well characterised but should be expected given the complex geographical, linguistic and cultural architecture of the Indonesian population. Here we use forensic short tandem repeat (STR) markers to identify a number of distinct genetic subpopulations within Indonesia and calculate appropriate population sub-structure correction factors. This data represents the most comprehensive investigation of population sub-structure within Indonesia to date using these markers. The results demonstrate that significant sub-structure is present within the Indonesian population and must be accounted for using island specific allele frequencies and corresponding substructure correction factors in the calculation of forensic DNA match statistics.",
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    Daniel, R, SARRE, S, Soedarsono, N, Sudoyo, H, Suryadi, H, van Oorschot, R, Walsh, S, Widodo, P & MCNEVIN, D 2016, 'Allele frequency data for 15 autosomal STR loci in eight Indonesian subpopulations', Forensic Science International: Genetics, vol. 20, pp. 45-52. https://doi.org/10.1016/j.fsigen.2015.09.014

    Allele frequency data for 15 autosomal STR loci in eight Indonesian subpopulations. / Daniel, Runa; SARRE, Stephen; Soedarsono, Nurtami; Sudoyo, Herawati; Suryadi, Helena; van Oorschot, Roland; Walsh, Simon; Widodo, Putut; MCNEVIN, Dennis.

    In: Forensic Science International: Genetics, Vol. 20, 2016, p. 45-52.

    Research output: Contribution to journalArticle

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    AU - van Oorschot, Roland

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