Abstract
Evolutionary and cultural history can affect the genetic characteristics of a population and influences the
frequency of different variants at a particular genetic marker (allele frequency). These characteristics
directly influence the strength of forensic DNA evidence and make the availability of suitable allele
frequency information for every discrete country or jurisdiction highly relevant. Population substructure
within Indonesia has not been well characterised but should be expected given the complex
geographical, linguistic and cultural architecture of the Indonesian population. Here we use forensic
short tandem repeat (STR) markers to identify a number of distinct genetic subpopulations within
Indonesia and calculate appropriate population sub-structure correction factors. This data represents the
most comprehensive investigation of population sub-structure within Indonesia to date using these
markers. The results demonstrate that significant sub-structure is present within the Indonesian
population and must be accounted for using island specific allele frequencies and corresponding substructure
correction factors in the calculation of forensic DNA match statistics.
Original language | English |
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Pages (from-to) | 45-52 |
Number of pages | 8 |
Journal | Forensic Science International: Genetics |
Volume | 20 |
DOIs | |
Publication status | Published - 2016 |