Analysis of Drosophila yellow-B cDNA reveals a new family of proteins related to the Royal Jelly proteins in the honeybee and to an orphan protein in an unusual bacterium Deinococcus radiodurans

R Maleszka, R Kucharski

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The yellow locus in Drosophila is involved in both cuticle development and behaviour. However, the function of the encoded protein is unknown. Here we have characterised the sequence and expression pattern of a new Drosophila gene, designated yellow-B, encoding a 453-amino-acid protein that is 57% identical to Yellow. High levels of yellow-B mRNA are present in the larval–pupal stages, but the gene is also expressed in the head. Bioinformatics analysis indicates that the Drosophila genome encodes at least 7 members of the Yellow family distributed among chromosomes 2, 3, and X. The Yellow proteins are related to the Royal Jelly proteins and have no relatives in other non-insect metazoan species. Interestingly, a Yellowlike protein is encoded by the genome of a radiation tolerant bacterium, Deinococcus radiodurans.
Original languageEnglish
Pages (from-to)773-776
Number of pages4
JournalBiochemical and Biophysical Research Communications
Volume270
Issue number3
DOIs
Publication statusPublished - 21 Apr 2000
Externally publishedYes

Cite this

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title = "Analysis of Drosophila yellow-B cDNA reveals a new family of proteins related to the Royal Jelly proteins in the honeybee and to an orphan protein in an unusual bacterium Deinococcus radiodurans",
abstract = "The yellow locus in Drosophila is involved in both cuticle development and behaviour. However, the function of the encoded protein is unknown. Here we have characterised the sequence and expression pattern of a new Drosophila gene, designated yellow-B, encoding a 453-amino-acid protein that is 57{\%} identical to Yellow. High levels of yellow-B mRNA are present in the larval–pupal stages, but the gene is also expressed in the head. Bioinformatics analysis indicates that the Drosophila genome encodes at least 7 members of the Yellow family distributed among chromosomes 2, 3, and X. The Yellow proteins are related to the Royal Jelly proteins and have no relatives in other non-insect metazoan species. Interestingly, a Yellowlike protein is encoded by the genome of a radiation tolerant bacterium, Deinococcus radiodurans.",
keywords = "yellow protein, Drosophila, Apis mellifera, insect brain, homopeptides, Royal Jelly proteins",
author = "R Maleszka and R Kucharski",
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TY - JOUR

T1 - Analysis of Drosophila yellow-B cDNA reveals a new family of proteins related to the Royal Jelly proteins in the honeybee and to an orphan protein in an unusual bacterium Deinococcus radiodurans

AU - Maleszka, R

AU - Kucharski, R

PY - 2000/4/21

Y1 - 2000/4/21

N2 - The yellow locus in Drosophila is involved in both cuticle development and behaviour. However, the function of the encoded protein is unknown. Here we have characterised the sequence and expression pattern of a new Drosophila gene, designated yellow-B, encoding a 453-amino-acid protein that is 57% identical to Yellow. High levels of yellow-B mRNA are present in the larval–pupal stages, but the gene is also expressed in the head. Bioinformatics analysis indicates that the Drosophila genome encodes at least 7 members of the Yellow family distributed among chromosomes 2, 3, and X. The Yellow proteins are related to the Royal Jelly proteins and have no relatives in other non-insect metazoan species. Interestingly, a Yellowlike protein is encoded by the genome of a radiation tolerant bacterium, Deinococcus radiodurans.

AB - The yellow locus in Drosophila is involved in both cuticle development and behaviour. However, the function of the encoded protein is unknown. Here we have characterised the sequence and expression pattern of a new Drosophila gene, designated yellow-B, encoding a 453-amino-acid protein that is 57% identical to Yellow. High levels of yellow-B mRNA are present in the larval–pupal stages, but the gene is also expressed in the head. Bioinformatics analysis indicates that the Drosophila genome encodes at least 7 members of the Yellow family distributed among chromosomes 2, 3, and X. The Yellow proteins are related to the Royal Jelly proteins and have no relatives in other non-insect metazoan species. Interestingly, a Yellowlike protein is encoded by the genome of a radiation tolerant bacterium, Deinococcus radiodurans.

KW - yellow protein

KW - Drosophila

KW - Apis mellifera

KW - insect brain

KW - homopeptides

KW - Royal Jelly proteins

U2 - 10.1006/bbrc.2000.2506

DO - 10.1006/bbrc.2000.2506

M3 - Article

VL - 270

SP - 773

EP - 776

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

SN - 0006-291X

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ER -