Animal and Human Models of Retinal Diseases

Erica L. Fletcher, Alice Pebay, Matt Rutar, Kiana Kakavand, Anna Y. Wang, Kirstan A. Vessey, Andrew I. Jobling, Ursula Greferath

Research output: A Conference proceeding or a Chapter in BookOther chapter contributionpeer-review

Abstract

Complex diseases of the retina are the leading causes of irreversible vision loss in industrialized nations. Often the first step in developing novel treatments for these diseases is the use of animal models to support investigations. There are many genetic and environmental models in rodents, cats, dogs and pigs which show features of age related macular degeneration, glaucoma and diabetic retinopathy. This chapter summarizes the most commonly available models and the features of human disease that they replicate.
Original languageEnglish
Title of host publicationThe Senses: A Comprehensive Reference
EditorsBernd Fritzsch
Place of PublicationUnited States
PublisherAcademic Press
Chapter1.36
Pages590-613
Number of pages24
Volume1
Edition2
ISBN (Electronic)9780128054093
ISBN (Print)9780128054086
DOIs
Publication statusPublished - 2020
Externally publishedYes

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