The use of Information and Communication Technologies (ICTs) plays a significant role in the economic, technological and social progression of a country. Corruption in government agencies and institutions is a serious problem in many countries in the world, especially in under-developed and developing countries. The use of ICT tools such as e-governance can help to reduce corruption. In this chapter, the authors discussed the application of e-government principles to mitigate corruption. Based on the available literature, this study identified some potential elements of e-government, which are currently practised around the world and how they are interrelated to fight against corruption. Finally, the authors present an evidence-based e-government anti-corruption framework.