Are some chromosomes particularly good at sex? Insights from amniotes

Denis O'Meally, Tariq Ezaz, Arthur Georges, Stephen Sarre, Jennifer Marshall-Graves

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Several recent studies have produced comparative maps of genes on amniote sex chromosomes, revealing homology of gene content and arrangement across lineages as divergent as mammals and lizards. For example, the chicken Z chromosome, which shares homology with the sex chromosomes of all birds, monotremes, and a gecko, is a striking example of stability of genome organization and retention, or independent acquisition, of function in sex determination. In other lineages, such as snakes and therian mammals, well conserved but independently evolved sex chromosome systems have arisen. Among lizards, novel sex chromosomes appear frequently, even in congeneric species. Here, we review recent gene mapping data, examine the evolutionary relationships of amniote sex chromosomes and argue that gene content can predispose some chromosomes to a specialized role in sex determination.
Original languageEnglish
Pages (from-to)7-19
Number of pages13
JournalChromosome Research
Volume20
Issue number1
DOIs
Publication statusPublished - 2012

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Sex Chromosomes
Chromosomes
Lizards
Mammals
Gene Order
Snakes
Genomic Instability
Chromosome Mapping
Genes
Birds
Chickens

Cite this

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Are some chromosomes particularly good at sex? Insights from amniotes. / O'Meally, Denis; Ezaz, Tariq; Georges, Arthur; Sarre, Stephen; Marshall-Graves, Jennifer.

In: Chromosome Research, Vol. 20, No. 1, 2012, p. 7-19.

Research output: Contribution to journalArticle

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