Assessing the performance of curtain flow first generation silica monoliths

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12 Citations (Scopus)

Abstract

Analytical scale active flow technology first generation silica monolithic columns kitted out in curtain flow mode of operation were studied for the first time. A series of tests were undertaken assessing the column efficiency, peak asymmetry and detection sensitivity. Two curtain flow columns were tested, one with a fixed outlet ratio of 10% through the central exit port, the other with 30%. Tests were carried out using a wide range in inlet flow segmentation ratios. The performance of the curtain flow columns were compared to a conventional monolithic column. The gain in theoretical plates achieved in the curtain flow mode of operation was as much as 130%, with almost Gaussian bands being obtained. Detection sensitivity increased by as much as 250% under optimal detection conditions. The permeability advantage of the monolithic structure together with the active flow technology makes it a priceless tool for high throughput, sensitive, low detection volume analyses.

Original languageEnglish
Pages (from-to)56-60
Number of pages5
JournalJournal of Australian Indigenous Issues
Volume1351
Issue number2
DOIs
Publication statusPublished - 18 Jul 2014
Externally publishedYes

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