TY - JOUR
T1 - Asymmetric catalysis in organic synthesis
AU - Adly, Frady G.
AU - Ghanem, Ashraf
PY - 2019
Y1 - 2019
N2 - Biological systems, in most cases, recognize a pair of enantiomers as different substances eliciting different responses. Therefore, one enantiomer may act as a very effective therapeutic agent whereas the other enantiomer, at worst, interacts with a totally different target resulting in undesired side effects. Thalidomide offers a tragic example that led to the death of approximately 2000 children and serious malformation of arms and legs in 10,000 babies born around the world.
AB - Biological systems, in most cases, recognize a pair of enantiomers as different substances eliciting different responses. Therefore, one enantiomer may act as a very effective therapeutic agent whereas the other enantiomer, at worst, interacts with a totally different target resulting in undesired side effects. Thalidomide offers a tragic example that led to the death of approximately 2000 children and serious malformation of arms and legs in 10,000 babies born around the world.
KW - Catalysis
UR - http://www.scopus.com/inward/record.url?scp=85073330841&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/asymmetric-catalysis-organic-synthesis
U2 - 10.3390/catal9090775
DO - 10.3390/catal9090775
M3 - Editorial
AN - SCOPUS:85073330841
SN - 2073-4344
VL - 9
SP - 1
EP - 2
JO - Catalysts
JF - Catalysts
IS - 9
M1 - 775
ER -