Asymmetric catalysis in organic synthesis

Frady G. Adly; Ashraf Ghanem

doi:10.3390/catal9090775

Asymmetric catalysis in organic synthesis

Frady G. Adly
, Ashraf Ghanem

Research output: Contribution to journal › Editorial

4 Citations (Scopus)

100 Downloads (Pure)

Abstract

Biological systems, in most cases, recognize a pair of enantiomers as different substances eliciting different responses. Therefore, one enantiomer may act as a very effective therapeutic agent whereas the other enantiomer, at worst, interacts with a totally different target resulting in undesired side effects. Thalidomide offers a tragic example that led to the death of approximately 2000 children and serious malformation of arms and legs in 10,000 babies born around the world.

Original language	English
Article number	775
Pages (from-to)	1-2
Number of pages	2
Journal	Catalysts
Volume	9
Issue number	9
DOIs	https://doi.org/10.3390/catal9090775
Publication status	Published - 2019

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10.3390/catal9090775Licence: CC BY

EditorialFinal published version, 167 KBLicence: CC BY

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title = "Asymmetric catalysis in organic synthesis",

abstract = "Biological systems, in most cases, recognize a pair of enantiomers as different substances eliciting different responses. Therefore, one enantiomer may act as a very effective therapeutic agent whereas the other enantiomer, at worst, interacts with a totally different target resulting in undesired side effects. Thalidomide offers a tragic example that led to the death of approximately 2000 children and serious malformation of arms and legs in 10,000 babies born around the world.",

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AU - Ghanem, Ashraf

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N2 - Biological systems, in most cases, recognize a pair of enantiomers as different substances eliciting different responses. Therefore, one enantiomer may act as a very effective therapeutic agent whereas the other enantiomer, at worst, interacts with a totally different target resulting in undesired side effects. Thalidomide offers a tragic example that led to the death of approximately 2000 children and serious malformation of arms and legs in 10,000 babies born around the world.

AB - Biological systems, in most cases, recognize a pair of enantiomers as different substances eliciting different responses. Therefore, one enantiomer may act as a very effective therapeutic agent whereas the other enantiomer, at worst, interacts with a totally different target resulting in undesired side effects. Thalidomide offers a tragic example that led to the death of approximately 2000 children and serious malformation of arms and legs in 10,000 babies born around the world.

KW - Catalysis

UR - https://www.scopus.com/pages/publications/85073330841

UR - http://www.mendeley.com/research/asymmetric-catalysis-organic-synthesis

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Asymmetric catalysis in organic synthesis

Abstract

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