Asymmetry of Cerebral Hemodynamic Response to Incremental Cycling Exercise

Mark Stone, Alan St Clair Gibson, Kevin THOMPSON

    Research output: Contribution to journalArticle

    Abstract

    Purpose: Exercise is known to result in hemodynamic changes in the bilateral prefrontal cortex. The aim of this study was to investigate hemodynamic changes in right and left hemispheres of the prefrontal cortex (PFC) during incremental cycling exercise. Methods: After 10 min rest, 9 participants (mean age 26.6 ± 2.5 y, mass 77.5 ± 9.7 kg, stature 1.79 ± 0.9 m) cycled at 100-150 W for 4 min. Thereafter, resistance was increased by 25 W every 4 min until exhaustion (EXH). Respiratory exchange and concentrations of oxy- ([HbO 2]), deoxy- ([ (HHb]), and total hemoglobin ([Hb tot]) in the PFC were continuously measured. Data were averaged for 60 s at rest and preceding ventilatory threshold 1 (VT 1), VT 2, and volitional EXH and after 5 min recovery. Subjective ratings of affect were measured at VT 1, VT 2, VT 1 minus 25 W (VT 1-25W), and VT 2 plus 25 W (VT 2+25W). Results: There were no between-hemispheres differences in [HbO 2] or [Hb tot] at rest, VT 1, or recovery or in [HHb] at any point. Right-hemisphere [HbO 2] and [Hb tot] were significantly greater than left at VT 2 (P = .01 and P = .02) and EXH (P = .03 and P = .02). Affect was significantly greater at VT 1-25W vs VT 2 and VT 2+25W and at VT 1 and VT 2 vs VT 2+25W (P < .01-.03). Conclusions: To the authors' knowledge, this is the first study to describe an exercise-state-dependent change in PFC asymmetry during incremental exercise. The asymmetry detected coincided with a decrease in affect scores in agreement with the PFC-asymmetry hypothesis.

    Original languageEnglish
    Pages (from-to)273-275
    Number of pages3
    JournalInternational Journal of Sports Physiology and Performance
    Volume11
    Issue number2
    DOIs
    Publication statusPublished - Mar 2016

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    Prefrontal Cortex
    Hemodynamics
    Hemoglobins

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    title = "Asymmetry of Cerebral Hemodynamic Response to Incremental Cycling Exercise",
    abstract = "Purpose: Exercise is known to result in hemodynamic changes in the bilateral prefrontal cortex. The aim of this study was to investigate hemodynamic changes in right and left hemispheres of the prefrontal cortex (PFC) during incremental cycling exercise. Methods: After 10 min rest, 9 participants (mean age 26.6 ± 2.5 y, mass 77.5 ± 9.7 kg, stature 1.79 ± 0.9 m) cycled at 100-150 W for 4 min. Thereafter, resistance was increased by 25 W every 4 min until exhaustion (EXH). Respiratory exchange and concentrations of oxy- ([HbO 2]), deoxy- ([ (HHb]), and total hemoglobin ([Hb tot]) in the PFC were continuously measured. Data were averaged for 60 s at rest and preceding ventilatory threshold 1 (VT 1), VT 2, and volitional EXH and after 5 min recovery. Subjective ratings of affect were measured at VT 1, VT 2, VT 1 minus 25 W (VT 1-25W), and VT 2 plus 25 W (VT 2+25W). Results: There were no between-hemispheres differences in [HbO 2] or [Hb tot] at rest, VT 1, or recovery or in [HHb] at any point. Right-hemisphere [HbO 2] and [Hb tot] were significantly greater than left at VT 2 (P = .01 and P = .02) and EXH (P = .03 and P = .02). Affect was significantly greater at VT 1-25W vs VT 2 and VT 2+25W and at VT 1 and VT 2 vs VT 2+25W (P < .01-.03). Conclusions: To the authors' knowledge, this is the first study to describe an exercise-state-dependent change in PFC asymmetry during incremental exercise. The asymmetry detected coincided with a decrease in affect scores in agreement with the PFC-asymmetry hypothesis.",
    keywords = "cerebral bloodflow, prefrontal cortex fatigue, prefrontal cortex asymmetry, Prefrontal cortex asymmetry, Cerebral bloodflow, Prefrontal cortex fatigue",
    author = "Mark Stone and Gibson, {Alan St Clair} and Kevin THOMPSON",
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    Asymmetry of Cerebral Hemodynamic Response to Incremental Cycling Exercise. / Stone, Mark; Gibson, Alan St Clair; THOMPSON, Kevin.

    In: International Journal of Sports Physiology and Performance, Vol. 11, No. 2, 03.2016, p. 273-275.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Asymmetry of Cerebral Hemodynamic Response to Incremental Cycling Exercise

    AU - Stone, Mark

    AU - Gibson, Alan St Clair

    AU - THOMPSON, Kevin

    PY - 2016/3

    Y1 - 2016/3

    N2 - Purpose: Exercise is known to result in hemodynamic changes in the bilateral prefrontal cortex. The aim of this study was to investigate hemodynamic changes in right and left hemispheres of the prefrontal cortex (PFC) during incremental cycling exercise. Methods: After 10 min rest, 9 participants (mean age 26.6 ± 2.5 y, mass 77.5 ± 9.7 kg, stature 1.79 ± 0.9 m) cycled at 100-150 W for 4 min. Thereafter, resistance was increased by 25 W every 4 min until exhaustion (EXH). Respiratory exchange and concentrations of oxy- ([HbO 2]), deoxy- ([ (HHb]), and total hemoglobin ([Hb tot]) in the PFC were continuously measured. Data were averaged for 60 s at rest and preceding ventilatory threshold 1 (VT 1), VT 2, and volitional EXH and after 5 min recovery. Subjective ratings of affect were measured at VT 1, VT 2, VT 1 minus 25 W (VT 1-25W), and VT 2 plus 25 W (VT 2+25W). Results: There were no between-hemispheres differences in [HbO 2] or [Hb tot] at rest, VT 1, or recovery or in [HHb] at any point. Right-hemisphere [HbO 2] and [Hb tot] were significantly greater than left at VT 2 (P = .01 and P = .02) and EXH (P = .03 and P = .02). Affect was significantly greater at VT 1-25W vs VT 2 and VT 2+25W and at VT 1 and VT 2 vs VT 2+25W (P < .01-.03). Conclusions: To the authors' knowledge, this is the first study to describe an exercise-state-dependent change in PFC asymmetry during incremental exercise. The asymmetry detected coincided with a decrease in affect scores in agreement with the PFC-asymmetry hypothesis.

    AB - Purpose: Exercise is known to result in hemodynamic changes in the bilateral prefrontal cortex. The aim of this study was to investigate hemodynamic changes in right and left hemispheres of the prefrontal cortex (PFC) during incremental cycling exercise. Methods: After 10 min rest, 9 participants (mean age 26.6 ± 2.5 y, mass 77.5 ± 9.7 kg, stature 1.79 ± 0.9 m) cycled at 100-150 W for 4 min. Thereafter, resistance was increased by 25 W every 4 min until exhaustion (EXH). Respiratory exchange and concentrations of oxy- ([HbO 2]), deoxy- ([ (HHb]), and total hemoglobin ([Hb tot]) in the PFC were continuously measured. Data were averaged for 60 s at rest and preceding ventilatory threshold 1 (VT 1), VT 2, and volitional EXH and after 5 min recovery. Subjective ratings of affect were measured at VT 1, VT 2, VT 1 minus 25 W (VT 1-25W), and VT 2 plus 25 W (VT 2+25W). Results: There were no between-hemispheres differences in [HbO 2] or [Hb tot] at rest, VT 1, or recovery or in [HHb] at any point. Right-hemisphere [HbO 2] and [Hb tot] were significantly greater than left at VT 2 (P = .01 and P = .02) and EXH (P = .03 and P = .02). Affect was significantly greater at VT 1-25W vs VT 2 and VT 2+25W and at VT 1 and VT 2 vs VT 2+25W (P < .01-.03). Conclusions: To the authors' knowledge, this is the first study to describe an exercise-state-dependent change in PFC asymmetry during incremental exercise. The asymmetry detected coincided with a decrease in affect scores in agreement with the PFC-asymmetry hypothesis.

    KW - cerebral bloodflow

    KW - prefrontal cortex fatigue

    KW - prefrontal cortex asymmetry

    KW - Prefrontal cortex asymmetry

    KW - Cerebral bloodflow

    KW - Prefrontal cortex fatigue

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    JO - International Journal of Sports Physiology and Performance

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    SN - 1555-0265

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