TY - JOUR
T1 - Asymmetry of Cerebral Hemodynamic Response to Incremental Cycling Exercise
AU - Stone, Mark
AU - Gibson, Alan St Clair
AU - THOMPSON, Kevin
PY - 2016/3
Y1 - 2016/3
N2 - Purpose: Exercise is known to result in hemodynamic changes in the bilateral prefrontal cortex. The aim of this study was to investigate hemodynamic changes in right and left hemispheres of the prefrontal cortex (PFC) during incremental cycling exercise. Methods: After 10 min rest, 9 participants (mean age 26.6 ± 2.5 y, mass 77.5 ± 9.7 kg, stature 1.79 ± 0.9 m) cycled at 100-150 W for 4 min. Thereafter, resistance was increased by 25 W every 4 min until exhaustion (EXH). Respiratory exchange and concentrations of oxy- ([HbO
2]), deoxy- ([ (HHb]), and total hemoglobin ([Hb
tot]) in the PFC were continuously measured. Data were averaged for 60 s at rest and preceding ventilatory threshold 1 (VT
1), VT
2, and volitional EXH and after 5 min recovery. Subjective ratings of affect were measured at VT
1, VT
2, VT
1 minus 25 W (VT
1-25W), and VT
2 plus 25 W (VT
2+25W). Results: There were no between-hemispheres differences in [HbO
2] or [Hb
tot] at rest, VT
1, or recovery or in [HHb] at any point. Right-hemisphere [HbO
2] and [Hb
tot] were significantly greater than left at VT
2 (P = .01 and P = .02) and EXH (P = .03 and P = .02). Affect was significantly greater at VT
1-25W vs VT
2 and VT
2+25W and at VT
1 and VT
2 vs VT
2+25W (P < .01-.03). Conclusions: To the authors' knowledge, this is the first study to describe an exercise-state-dependent change in PFC asymmetry during incremental exercise. The asymmetry detected coincided with a decrease in affect scores in agreement with the PFC-asymmetry hypothesis.
AB - Purpose: Exercise is known to result in hemodynamic changes in the bilateral prefrontal cortex. The aim of this study was to investigate hemodynamic changes in right and left hemispheres of the prefrontal cortex (PFC) during incremental cycling exercise. Methods: After 10 min rest, 9 participants (mean age 26.6 ± 2.5 y, mass 77.5 ± 9.7 kg, stature 1.79 ± 0.9 m) cycled at 100-150 W for 4 min. Thereafter, resistance was increased by 25 W every 4 min until exhaustion (EXH). Respiratory exchange and concentrations of oxy- ([HbO
2]), deoxy- ([ (HHb]), and total hemoglobin ([Hb
tot]) in the PFC were continuously measured. Data were averaged for 60 s at rest and preceding ventilatory threshold 1 (VT
1), VT
2, and volitional EXH and after 5 min recovery. Subjective ratings of affect were measured at VT
1, VT
2, VT
1 minus 25 W (VT
1-25W), and VT
2 plus 25 W (VT
2+25W). Results: There were no between-hemispheres differences in [HbO
2] or [Hb
tot] at rest, VT
1, or recovery or in [HHb] at any point. Right-hemisphere [HbO
2] and [Hb
tot] were significantly greater than left at VT
2 (P = .01 and P = .02) and EXH (P = .03 and P = .02). Affect was significantly greater at VT
1-25W vs VT
2 and VT
2+25W and at VT
1 and VT
2 vs VT
2+25W (P < .01-.03). Conclusions: To the authors' knowledge, this is the first study to describe an exercise-state-dependent change in PFC asymmetry during incremental exercise. The asymmetry detected coincided with a decrease in affect scores in agreement with the PFC-asymmetry hypothesis.
KW - cerebral bloodflow
KW - prefrontal cortex fatigue
KW - prefrontal cortex asymmetry
KW - Prefrontal cortex asymmetry
KW - Cerebral bloodflow
KW - Prefrontal cortex fatigue
UR - http://www.scopus.com/inward/record.url?scp=84960898052&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/asymmetry-cerebral-hemodynamic-response-incremental-cycling-exercise
U2 - 10.1123/ijspp.2015-0168
DO - 10.1123/ijspp.2015-0168
M3 - Article
C2 - 26218443
SN - 1555-0265
VL - 11
SP - 273
EP - 275
JO - International Journal of Sports Physiology and Performance
JF - International Journal of Sports Physiology and Performance
IS - 2
ER -