Abstract
Reference limits or intervals are important benchmarks or tools that help the clinician to distinguish between a result that is most likely to lie within a ‘healthy’ or diseased category. It has been suggested that a review of haematology reference intervals is long overdue. In this study we report on our findings for analytes routinely measured in a complete blood count (CBC) performed on the Beckman Coulter LH 750 analyser and an additional comparative study using the Beckman Coulter LH 750, the Sysmex XN and Abbott Sapphire. The results from the comparative study indicate that bias would not prevent harmonisation of reference intervals for these common haematology parameters. The results offered by the Aussie Normals study represent good candidates as the basis for harmonisation reference intervals.
| Original language | English |
|---|---|
| Pages (from-to) | 518-525 |
| Number of pages | 8 |
| Journal | Pathology |
| Volume | 49 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1 Aug 2017 |
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‘Aussie Normals’ : an a priori study to develop reference intervals in a healthy Australian population using the Beckman Coulter LH 750 Haematology Analyser as candidates for harmonised values. / Koerbin, G.; Potter, J. M.; Andriolo, K.; West, N. P.; Glasgow, N.; Hawkins, C.; Cavanaugh, J. A.; Hickman, P. E.
In: Pathology, Vol. 49, No. 5, 01.08.2017, p. 518-525.Research output: Contribution to journal › Article
TY - JOUR
T1 - ‘Aussie Normals’
T2 - an a priori study to develop reference intervals in a healthy Australian population using the Beckman Coulter LH 750 Haematology Analyser as candidates for harmonised values
AU - Koerbin, G.
AU - Potter, J. M.
AU - Andriolo, K.
AU - West, N. P.
AU - Glasgow, N.
AU - Hawkins, C.
AU - Cavanaugh, J. A.
AU - Hickman, P. E.
PY - 2017/8/1
Y1 - 2017/8/1
N2 - Reference limits or intervals are important benchmarks or tools that help the clinician to distinguish between a result that is most likely to lie within a ‘healthy’ or diseased category. It has been suggested that a review of haematology reference intervals is long overdue. In this study we report on our findings for analytes routinely measured in a complete blood count (CBC) performed on the Beckman Coulter LH 750 analyser and an additional comparative study using the Beckman Coulter LH 750, the Sysmex XN and Abbott Sapphire. The results from the comparative study indicate that bias would not prevent harmonisation of reference intervals for these common haematology parameters. The results offered by the Aussie Normals study represent good candidates as the basis for harmonisation reference intervals.
AB - Reference limits or intervals are important benchmarks or tools that help the clinician to distinguish between a result that is most likely to lie within a ‘healthy’ or diseased category. It has been suggested that a review of haematology reference intervals is long overdue. In this study we report on our findings for analytes routinely measured in a complete blood count (CBC) performed on the Beckman Coulter LH 750 analyser and an additional comparative study using the Beckman Coulter LH 750, the Sysmex XN and Abbott Sapphire. The results from the comparative study indicate that bias would not prevent harmonisation of reference intervals for these common haematology parameters. The results offered by the Aussie Normals study represent good candidates as the basis for harmonisation reference intervals.
KW - bias
KW - Haematology
KW - harmonisation
KW - reference intervals
UR - http://www.scopus.com/inward/record.url?scp=85022045465&partnerID=8YFLogxK
U2 - 10.1016/j.pathol.2017.04.003
DO - 10.1016/j.pathol.2017.04.003
M3 - Article
VL - 49
SP - 518
EP - 525
JO - Pathology
JF - Pathology
SN - 0031-3025
IS - 5
ER -