Biopsychosocial determinants of pregnancy length and fetal growth

Jennifer St-Laurent, Philippe De Wals, Jean Marie Moutquin, Theophile Niyonsenga, Manon Noiseux, Loretta Czernis

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The causes and mechanisms related to preterm delivery and intrauterine growth restriction are poorly understood. Our objective was to assess the direct and indirect effects of psychosocial and biomedical factors on the duration of pregnancy and fetal growth. A self-administered questionnaire was distributed to pregnant women attending prenatal ultrasound clinics in nine hospitals in the Montérégie region in the province of Quebec, Canada, from November 1997 to May 1998. Prenatal questionnaires were linked with birth certificates. Theoretical models explaining pregnancy length and fetal growth were developed and tested, using path analysis. In order to reduce the number of variables from the questionnaire, a principal component analysis was performed, and the three most important new dimensions were retained as explanatory variables in the final models. Data were available for 1602 singleton pregnancies. The biophysical score, covering both maternal age and the pre-pregnancy body mass index, was the only variable statistically associated with pregnancy length. Smoking, obstetric history, maternal health and biophysical indices were direct predictors of fetal growth. Perceived stress, social support and self-esteem were not directly related to pregnancy outcomes, but were determinants of smoking and the above-mentioned biomedical variables. More studies are needed to identify the mechanisms by which adverse psychosocial factors are translated into adverse biological effects.

Original languageEnglish
Pages (from-to)240-248
Number of pages9
JournalPaediatric and Perinatal Epidemiology
Volume22
Issue number3
DOIs
Publication statusPublished - 1 May 2008
Externally publishedYes

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Fetal Development
Pregnancy
Smoking
Psychology
Birth Certificates
Quebec
Maternal Age
Pregnancy Outcome
Principal Component Analysis
Self Concept
Social Support
Obstetrics
Canada
Pregnant Women
Body Mass Index
Theoretical Models
History
Growth
Surveys and Questionnaires

Cite this

St-Laurent, Jennifer ; De Wals, Philippe ; Moutquin, Jean Marie ; Niyonsenga, Theophile ; Noiseux, Manon ; Czernis, Loretta. / Biopsychosocial determinants of pregnancy length and fetal growth. In: Paediatric and Perinatal Epidemiology. 2008 ; Vol. 22, No. 3. pp. 240-248.
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Biopsychosocial determinants of pregnancy length and fetal growth. / St-Laurent, Jennifer; De Wals, Philippe; Moutquin, Jean Marie; Niyonsenga, Theophile; Noiseux, Manon; Czernis, Loretta.

In: Paediatric and Perinatal Epidemiology, Vol. 22, No. 3, 01.05.2008, p. 240-248.

Research output: Contribution to journalArticle

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