C11-Chirasil-Dex as chiral stationary phase in GC

enantioselective separation of cyclopropane derivatives

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Chirasil-β-Dex containing an undecamethylene spacer (C11-Chirasil-Dex) was used as chiral stationary phase (CSP) in enantioselective gas chromatography (GC). The versatility of the new stationary phase in the simultaneous enantiomeric separation of a set of cyclopropane derivatives is demonstrated. The GC method provides information about the chemical yields of the cyclopropane products, enantioselectivity, substrate specifity, and catalytic activity of the chiral catalysts used in the intermolecular cyclopropanation of olefins and avoids time-consuming work-up procedures.

Original languageEnglish
Pages (from-to)1234-1241
Number of pages8
JournalTalanta
Volume66
Issue number5
DOIs
Publication statusPublished - 15 Jun 2005
Externally publishedYes

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Gas chromatography
Derivatives
Enantioselectivity
Alkenes
Catalyst activity
Catalysts
Substrates
Chirasil-Dex
cyclopropane

Cite this

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abstract = "Chirasil-β-Dex containing an undecamethylene spacer (C11-Chirasil-Dex) was used as chiral stationary phase (CSP) in enantioselective gas chromatography (GC). The versatility of the new stationary phase in the simultaneous enantiomeric separation of a set of cyclopropane derivatives is demonstrated. The GC method provides information about the chemical yields of the cyclopropane products, enantioselectivity, substrate specifity, and catalytic activity of the chiral catalysts used in the intermolecular cyclopropanation of olefins and avoids time-consuming work-up procedures.",
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C11-Chirasil-Dex as chiral stationary phase in GC : enantioselective separation of cyclopropane derivatives. / Ghanem, Ashraf.

In: Talanta, Vol. 66, No. 5, 15.06.2005, p. 1234-1241.

Research output: Contribution to journalArticle

TY - JOUR

T1 - C11-Chirasil-Dex as chiral stationary phase in GC

T2 - enantioselective separation of cyclopropane derivatives

AU - Ghanem, Ashraf

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