Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels

Kafa Walweel; Nieves Gomez-Hurtado; Ye Wint Oo; Nicole A. Beard; Cris dos Remedios; Christopher N. Johnson; Walter J. Chazin; Dirk F. van Helden; Björn C. Knollmann; Derek R. Laver

doi:10.1016/j.jacc.2017.04.055

Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels

Kafa Walweel
, Nieves Gomez-Hurtado
, Ye Wint Oo
, Nicole A. Beard
, Cris dos Remedios
, Christopher N. Johnson
, Walter J. Chazin
, Dirk F. van Helden
, Björn C. Knollmann
, Derek R. Laver

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	115-117
Number of pages	3
Journal	Journal of the American College of Cardiology
Volume	70
Issue number	1
DOIs	https://doi.org/10.1016/j.jacc.2017.04.055
Publication status	Published - 4 Jul 2017

Access to Document

10.1016/j.jacc.2017.04.055

Cite this

Walweel, K., Gomez-Hurtado, N., Oo, Y. W., Beard, N. A., dos Remedios, C., Johnson, C. N., Chazin, W. J., van Helden, D. F., Knollmann, B. C., & Laver, D. R. (2017). Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels. Journal of the American College of Cardiology, 70(1), 115-117. https://doi.org/10.1016/j.jacc.2017.04.055

@article{fa2f4bd591af4adb86bc0beb019b9f55,

title = "Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels",

author = "Kafa Walweel and Nieves Gomez-Hurtado and Oo, \{Ye Wint\} and Beard, \{Nicole A.\} and \{dos Remedios\}, Cris and Johnson, \{Christopher N.\} and Chazin, \{Walter J.\} and \{van Helden\}, \{Dirk F.\} and Knollmann, \{Bj{\"o}rn C.\} and Laver, \{Derek R.\}",

note = "Funding Information: Please note: Dr. Chazin was supported in part by a grant from the National Institutes of Health (R35 GM118089). Dr. Laver was supported by a Project Grant (APP1082204) from the National Health and Medical Research Council, Canberra, Australian Capital Territory, Australia, and by an infrastructure grant from the Hunter Medical Research Institute, Newcastle, New South Wales, Australia. Dr. Knollmann was supported in part by grants from the National Institutes of Health (R01HL128044, R01HL124935, R01HL108173) and by a Project Grant (APP1082204) from the National Health and Medical Research Council, Canberra. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. The authors wish to thank Mr. Paul Johnson for his assistance with the experiments.",

year = "2017",

month = jul,

day = "4",

doi = "10.1016/j.jacc.2017.04.055",

language = "English",

volume = "70",

pages = "115--117",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier USA",

number = "1",

}

Walweel, K, Gomez-Hurtado, N, Oo, YW, Beard, NA, dos Remedios, C, Johnson, CN, Chazin, WJ, van Helden, DF, Knollmann, BC & Laver, DR 2017, 'Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels', Journal of the American College of Cardiology, vol. 70, no. 1, pp. 115-117. https://doi.org/10.1016/j.jacc.2017.04.055

TY - JOUR

T1 - Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels

AU - Walweel, Kafa

AU - Gomez-Hurtado, Nieves

AU - Oo, Ye Wint

AU - Beard, Nicole A.

AU - dos Remedios, Cris

AU - Johnson, Christopher N.

AU - Chazin, Walter J.

AU - van Helden, Dirk F.

AU - Knollmann, Björn C.

AU - Laver, Derek R.

N1 - Funding Information: Please note: Dr. Chazin was supported in part by a grant from the National Institutes of Health (R35 GM118089). Dr. Laver was supported by a Project Grant (APP1082204) from the National Health and Medical Research Council, Canberra, Australian Capital Territory, Australia, and by an infrastructure grant from the Hunter Medical Research Institute, Newcastle, New South Wales, Australia. Dr. Knollmann was supported in part by grants from the National Institutes of Health (R01HL128044, R01HL124935, R01HL108173) and by a Project Grant (APP1082204) from the National Health and Medical Research Council, Canberra. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. The authors wish to thank Mr. Paul Johnson for his assistance with the experiments.

PY - 2017/7/4

Y1 - 2017/7/4

UR - https://www.scopus.com/pages/publications/85033222865

UR - http://www.mendeley.com/research/calmodulin-mutants-linked-catecholaminergic-polymorphic-ventricular-tachycardia-fail-inhibit-human-r

U2 - 10.1016/j.jacc.2017.04.055

DO - 10.1016/j.jacc.2017.04.055

M3 - Letter

AN - SCOPUS:85033222865

SN - 0735-1097

VL - 70

SP - 115

EP - 117

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 1

ER -

Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels

Access to Document

Other files and links

Cite this