Carbohydrate metabolism genes and pathways in insects

insights from the honey bee genome

T. Kunieda, T. Fujiyuki, R. Kucharski, S. Foret, S. A. Ament, A. L. Toth, K. Ohashi, H. Takeuchi, A. Kamikouchi, E. Kage, M. Morioka, M. Beye, T. Kubo, G. E. Robinson, R. Maleszka

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

Carbohydrate-metabolizing enzymes may have particularly interesting roles in the honey bee, Apis mellifera , because this social insect has an extremely carbohydrate-rich diet, and nutrition plays important roles in caste determination and socially mediated behavioural plasticity. We annotated a total of 174 genes encoding carbohydrate-metabolizing enzymes and 28 genes encoding lipid-metabolizing enzymes, based on orthology to their counterparts in the fly, Drosophila melanogaster, and the mosquito, Anopheles gambiae . We found that the number of genes for carbohydrate metabolism appears to be more evolutionarily labile than for lipid metabolism. In particular, we identified striking changes in gene number or genomic organiza- tion for genes encoding glycolytic enzymes, cellulase, glucose oxidase and glucose dehydrogenases, glucose- methanol-choline (GMC) oxidoreductases, fucosyltrans- ferases, and lysozymes.
Original languageEnglish
Pages (from-to)563-576
Number of pages14
JournalInsect Molecular Biology
Volume15
Issue number5
DOIs
Publication statusPublished - Oct 2006
Externally publishedYes

Cite this

Kunieda, T., Fujiyuki, T., Kucharski, R., Foret, S., Ament, S. A., Toth, A. L., ... Maleszka, R. (2006). Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome. Insect Molecular Biology, 15(5), 563-576. https://doi.org/10.1111/j.1365-2583.2006.00677.x
Kunieda, T. ; Fujiyuki, T. ; Kucharski, R. ; Foret, S. ; Ament, S. A. ; Toth, A. L. ; Ohashi, K. ; Takeuchi, H. ; Kamikouchi, A. ; Kage, E. ; Morioka, M. ; Beye, M. ; Kubo, T. ; Robinson, G. E. ; Maleszka, R. / Carbohydrate metabolism genes and pathways in insects : insights from the honey bee genome. In: Insect Molecular Biology. 2006 ; Vol. 15, No. 5. pp. 563-576.
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Kunieda, T, Fujiyuki, T, Kucharski, R, Foret, S, Ament, SA, Toth, AL, Ohashi, K, Takeuchi, H, Kamikouchi, A, Kage, E, Morioka, M, Beye, M, Kubo, T, Robinson, GE & Maleszka, R 2006, 'Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome', Insect Molecular Biology, vol. 15, no. 5, pp. 563-576. https://doi.org/10.1111/j.1365-2583.2006.00677.x

Carbohydrate metabolism genes and pathways in insects : insights from the honey bee genome. / Kunieda, T.; Fujiyuki, T.; Kucharski, R.; Foret, S.; Ament, S. A.; Toth, A. L.; Ohashi, K.; Takeuchi, H.; Kamikouchi, A.; Kage, E.; Morioka, M.; Beye, M.; Kubo, T.; Robinson, G. E.; Maleszka, R.

In: Insect Molecular Biology, Vol. 15, No. 5, 10.2006, p. 563-576.

Research output: Contribution to journalArticle

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T1 - Carbohydrate metabolism genes and pathways in insects

T2 - insights from the honey bee genome

AU - Kunieda, T.

AU - Fujiyuki, T.

AU - Kucharski, R.

AU - Foret, S.

AU - Ament, S. A.

AU - Toth, A. L.

AU - Ohashi, K.

AU - Takeuchi, H.

AU - Kamikouchi, A.

AU - Kage, E.

AU - Morioka, M.

AU - Beye, M.

AU - Kubo, T.

AU - Robinson, G. E.

AU - Maleszka, R.

PY - 2006/10

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AB - Carbohydrate-metabolizing enzymes may have particularly interesting roles in the honey bee, Apis mellifera , because this social insect has an extremely carbohydrate-rich diet, and nutrition plays important roles in caste determination and socially mediated behavioural plasticity. We annotated a total of 174 genes encoding carbohydrate-metabolizing enzymes and 28 genes encoding lipid-metabolizing enzymes, based on orthology to their counterparts in the fly, Drosophila melanogaster, and the mosquito, Anopheles gambiae . We found that the number of genes for carbohydrate metabolism appears to be more evolutionarily labile than for lipid metabolism. In particular, we identified striking changes in gene number or genomic organiza- tion for genes encoding glycolytic enzymes, cellulase, glucose oxidase and glucose dehydrogenases, glucose- methanol-choline (GMC) oxidoreductases, fucosyltrans- ferases, and lysozymes.

KW - insect metabolome

KW - lipid metabolism

KW - cellulose degradation

KW - gene synteny

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DO - 10.1111/j.1365-2583.2006.00677.x

M3 - Article

VL - 15

SP - 563

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JO - Insect Molecular Biology

JF - Insect Molecular Biology

SN - 0962-1075

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