TY - JOUR
T1 - Carbohydrate metabolism genes and pathways in insects
T2 - insights from the honey bee genome
AU - Kunieda, T.
AU - Fujiyuki, T.
AU - Kucharski, R.
AU - Foret, S.
AU - Ament, S. A.
AU - Toth, A. L.
AU - Ohashi, K.
AU - Takeuchi, H.
AU - Kamikouchi, A.
AU - Kage, E.
AU - Morioka, M.
AU - Beye, M.
AU - Kubo, T.
AU - Robinson, G. E.
AU - Maleszka, R.
PY - 2006/10
Y1 - 2006/10
N2 - Carbohydrate-metabolizing enzymes may have particularly interesting roles in the honey bee, Apis mellifera , because this social insect has an extremely carbohydrate-rich diet, and nutrition plays important roles in caste determination and socially mediated behavioural plasticity. We annotated a total of 174 genes encoding carbohydrate-metabolizing enzymes and 28 genes encoding lipid-metabolizing enzymes, based on orthology to their counterparts in the fly, Drosophila melanogaster, and the mosquito, Anopheles gambiae . We found that the number of genes for carbohydrate metabolism appears to be more evolutionarily labile than for lipid metabolism. In particular, we identified striking changes in gene number or genomic organiza- tion for genes encoding glycolytic enzymes, cellulase, glucose oxidase and glucose dehydrogenases, glucose- methanol-choline (GMC) oxidoreductases, fucosyltrans- ferases, and lysozymes.
AB - Carbohydrate-metabolizing enzymes may have particularly interesting roles in the honey bee, Apis mellifera , because this social insect has an extremely carbohydrate-rich diet, and nutrition plays important roles in caste determination and socially mediated behavioural plasticity. We annotated a total of 174 genes encoding carbohydrate-metabolizing enzymes and 28 genes encoding lipid-metabolizing enzymes, based on orthology to their counterparts in the fly, Drosophila melanogaster, and the mosquito, Anopheles gambiae . We found that the number of genes for carbohydrate metabolism appears to be more evolutionarily labile than for lipid metabolism. In particular, we identified striking changes in gene number or genomic organiza- tion for genes encoding glycolytic enzymes, cellulase, glucose oxidase and glucose dehydrogenases, glucose- methanol-choline (GMC) oxidoreductases, fucosyltrans- ferases, and lysozymes.
KW - insect metabolome
KW - lipid metabolism
KW - cellulose degradation
KW - gene synteny
U2 - 10.1111/j.1365-2583.2006.00677.x
DO - 10.1111/j.1365-2583.2006.00677.x
M3 - Article
SN - 0962-1075
VL - 15
SP - 563
EP - 576
JO - Insect Molecular Biology
JF - Insect Molecular Biology
IS - 5
ER -