Cardiovascular function and the veteran athlete

M. Wilson, R. O'Hanlon, S. Basavarajaiah, K. George, D. Green, P. Ainslie, S. Sharma, S. Prasad, C. Murrell, D. Thijssen, A. Nevill, G. Whyte

Research output: Contribution to journalReview articlepeer-review

26 Citations (Scopus)


The cardiovascular benefits of exercise are well known. In contrast, the impact of lifelong endurance exercise is less well understood. Long-term high-intensity endurance exercise is associated with changes in cardiac morphology together with electrocardiographic alterations that are believed to be physiologic in nature. Recent data however has suggested a number of deleterious adaptive changes in cardiac structure, function and electrical activity, together with peripheral and cerebral vascular structure and function. This review serves to detail knowledge in relation to; (1) Cardiac structure and function in veteran endurance athletes focusing on the differentiation of physiological and pathological changes in cardiac remodelling; (2) Cardiac electrical activity and the veteran endurance athlete with attention to arrhythmias, the substrate for arrhythmia generation and the clinical significance of such arrhythmias; (3) Peripheral and cerebral vascular structure and function in ageing and endurance-trained individuals; and (4) directions for future research.

Original languageEnglish
Pages (from-to)459-478
Number of pages20
JournalEuropean Journal of Applied Physiology
Issue number3
Publication statusPublished - Oct 2010
Externally publishedYes


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