Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study

international collaboration research overview

Ezekiel Uba Nwose, Ross Stuart Richards, Kester Digban, Philip Taderera Bwititi, Gretchen Ennis, Kwang Choon Yee, Victor Maduabuchi Oguoma, Selma Liberato

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The study aims to develop a screening protocol for the risk of future cardiovascular disease and diabetes mellitus in people with prediabetes and undiagnosed diabetes; and to establish a framework for early identification and intervention of prediabetes including strategies for holistic management and monitoring of progression. The first phase is to identify prediabetes and undiagnosed diabetes in volunteers who are ≥18-years-old for 5 years. Point-of-care testing and questionnaire will be used to screen for prediabetes and cardiovascular disease. We anticipate screening more than 2000 individuals of both genders by the end of first phase. The second and third phases which shall run for 5-10 years will be longitudinal study involving participants identified in the first phase as having prediabetes without dyslipidaemia, or clinically established cardiovascular disease. The second phase shall focus on preventive management of risk of progress to diabetes with explicit diagnosis of cardiovascular disease. Oxidative stress measurements will be performed cum evaluation of the use of antioxidants, exercise, and nutrition. The third phase will include probing the development of diabetes and cardiovascular disease. Binomial logistic regression would be performed to generate and propose a model chart for the assessment of cardiovascular disease risk in prediabetes.

Original languageEnglish
Pages (from-to)625-30
Number of pages6
JournalNorth American Journal of Medical Sciences
Volume5
Issue number11
DOIs
Publication statusPublished - Nov 2013
Externally publishedYes

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Prediabetic State
Diabetes Mellitus
Cardiovascular Diseases
Research
Risk Management
Dyslipidemias
Longitudinal Studies
Volunteers
Oxidative Stress
Antioxidants
Logistic Models
Exercise

Cite this

Nwose, Ezekiel Uba ; Richards, Ross Stuart ; Digban, Kester ; Bwititi, Philip Taderera ; Ennis, Gretchen ; Yee, Kwang Choon ; Oguoma, Victor Maduabuchi ; Liberato, Selma. / Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study : international collaboration research overview. In: North American Journal of Medical Sciences. 2013 ; Vol. 5, No. 11. pp. 625-30.
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Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study : international collaboration research overview. / Nwose, Ezekiel Uba; Richards, Ross Stuart; Digban, Kester; Bwititi, Philip Taderera; Ennis, Gretchen; Yee, Kwang Choon; Oguoma, Victor Maduabuchi; Liberato, Selma.

In: North American Journal of Medical Sciences, Vol. 5, No. 11, 11.2013, p. 625-30.

Research output: Contribution to journalArticle

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