Central Mechanism of Hyperphagia in a Mouse Model of Obesity-Related Liver Disease

Deborah HEYDET; Claire Larter; C Farrell

doi:10.1111/j.1440-1746.2009.06055.x

Central Mechanism of Hyperphagia in a Mouse Model of Obesity-Related Liver Disease

Deborah HEYDET, Claire Larter, C Farrell

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Research output: Contribution to conference (non-published works) › Abstract › peer-review

Abstract

Diet-induced obesity is associated with hyperphagia and increased serum leptin, a central satiety regulator. Our aim was to study hypothalamic changes related to appetite regulation in Alms1 mutant (foz/foz) mice, a murine model of Alström syndrome; the latter is a form of monogenic obesity associated with cilia disorder, diabetes and NASH.

Original language	English
Pages	277-277
Number of pages	1
DOIs	https://doi.org/10.1111/j.1440-1746.2009.06055.x
Publication status	Published - 2009
Event	Australia & New Zealand Medical & Surgical Gastrointestinal Week - Sydney, Australia Duration: 1 Oct 2009 → …

Conference

Conference	Australia & New Zealand Medical & Surgical Gastrointestinal Week
Country/Territory	Australia
City	Sydney
Period	1/10/09 → …

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1440-1746.2009.06055.x

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title = "Central Mechanism of Hyperphagia in a Mouse Model of Obesity-Related Liver Disease",

abstract = "Diet-induced obesity is associated with hyperphagia and increased serum leptin, a central satiety regulator. Our aim was to study hypothalamic changes related to appetite regulation in Alms1 mutant (foz/foz) mice, a murine model of Alstr{\"o}m syndrome; the latter is a form of monogenic obesity associated with cilia disorder, diabetes and NASH.",

keywords = "Alms1 mutation, Neuropeptides, Obesity",

author = "Deborah HEYDET and Claire Larter and C Farrell",

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doi = "10.1111/j.1440-1746.2009.06055.x",

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AU - HEYDET, Deborah

AU - Larter, Claire

AU - Farrell, C

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N2 - Diet-induced obesity is associated with hyperphagia and increased serum leptin, a central satiety regulator. Our aim was to study hypothalamic changes related to appetite regulation in Alms1 mutant (foz/foz) mice, a murine model of Alström syndrome; the latter is a form of monogenic obesity associated with cilia disorder, diabetes and NASH.

AB - Diet-induced obesity is associated with hyperphagia and increased serum leptin, a central satiety regulator. Our aim was to study hypothalamic changes related to appetite regulation in Alms1 mutant (foz/foz) mice, a murine model of Alström syndrome; the latter is a form of monogenic obesity associated with cilia disorder, diabetes and NASH.

KW - Alms1 mutation

KW - Neuropeptides

KW - Obesity

U2 - 10.1111/j.1440-1746.2009.06055.x

DO - 10.1111/j.1440-1746.2009.06055.x

M3 - Abstract

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EP - 277

T2 - Australia & New Zealand Medical & Surgical Gastrointestinal Week

Y2 - 1 October 2009

ER -

Central Mechanism of Hyperphagia in a Mouse Model of Obesity-Related Liver Disease

Abstract

Conference

UN SDGs

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