Challenges and Opportunities in the Management of Onychomycosis

Julia K. Christenson, Gregory M. Peterson, Mark Naunton, Mary Bushell, Sam Kosari, Kavya E. Baby, Jackson Thomas

Research output: Contribution to journalReview article

3 Citations (Scopus)
3 Downloads (Pure)

Abstract

Onychomycosis is an increasingly common fungal nail infection, chiefly caused by dermatophyte fungi. The disease is notoriously difficult to treat due to the deep-seated nature of fungi within the nail plate, prolonged treatment requirements, poor patient adherence and frequent recurrences. Given the poor efficacy of currently available topical and systemic therapies, there is a renewed interest in exploring alternative treatment modalities for onychomycosis. Natural therapies, physical treatments and various combination therapies have all shown potential for the management of onychomycosis, though research on many of these methods is still in preliminary stages. Further large, well-designed, randomised controlled trials are necessary to confirm the efficacy of these novel treatments in order to make formal recommendations regarding their use in the management of onychomycosis.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalJournal of fungi (Basel, Switzerland)
Volume4
Issue number87
DOIs
Publication statusPublished - 24 Jul 2018

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Onychomycosis
Arthrodermataceae
Mycoses
Patient Compliance
Nails
Fungi
Therapeutics
Randomized Controlled Trials
Recurrence
Research

Cite this

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title = "Challenges and Opportunities in the Management of Onychomycosis",
abstract = "Onychomycosis is an increasingly common fungal nail infection, chiefly caused by dermatophyte fungi. The disease is notoriously difficult to treat due to the deep-seated nature of fungi within the nail plate, prolonged treatment requirements, poor patient adherence and frequent recurrences. Given the poor efficacy of currently available topical and systemic therapies, there is a renewed interest in exploring alternative treatment modalities for onychomycosis. Natural therapies, physical treatments and various combination therapies have all shown potential for the management of onychomycosis, though research on many of these methods is still in preliminary stages. Further large, well-designed, randomised controlled trials are necessary to confirm the efficacy of these novel treatments in order to make formal recommendations regarding their use in the management of onychomycosis.",
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Challenges and Opportunities in the Management of Onychomycosis. / Christenson, Julia K.; Peterson, Gregory M.; Naunton, Mark; Bushell, Mary; Kosari, Sam; Baby, Kavya E.; Thomas, Jackson.

In: Journal of fungi (Basel, Switzerland), Vol. 4, No. 87, 24.07.2018, p. 1-10.

Research output: Contribution to journalReview article

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T1 - Challenges and Opportunities in the Management of Onychomycosis

AU - Christenson, Julia K.

AU - Peterson, Gregory M.

AU - Naunton, Mark

AU - Bushell, Mary

AU - Kosari, Sam

AU - Baby, Kavya E.

AU - Thomas, Jackson

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N2 - Onychomycosis is an increasingly common fungal nail infection, chiefly caused by dermatophyte fungi. The disease is notoriously difficult to treat due to the deep-seated nature of fungi within the nail plate, prolonged treatment requirements, poor patient adherence and frequent recurrences. Given the poor efficacy of currently available topical and systemic therapies, there is a renewed interest in exploring alternative treatment modalities for onychomycosis. Natural therapies, physical treatments and various combination therapies have all shown potential for the management of onychomycosis, though research on many of these methods is still in preliminary stages. Further large, well-designed, randomised controlled trials are necessary to confirm the efficacy of these novel treatments in order to make formal recommendations regarding their use in the management of onychomycosis.

AB - Onychomycosis is an increasingly common fungal nail infection, chiefly caused by dermatophyte fungi. The disease is notoriously difficult to treat due to the deep-seated nature of fungi within the nail plate, prolonged treatment requirements, poor patient adherence and frequent recurrences. Given the poor efficacy of currently available topical and systemic therapies, there is a renewed interest in exploring alternative treatment modalities for onychomycosis. Natural therapies, physical treatments and various combination therapies have all shown potential for the management of onychomycosis, though research on many of these methods is still in preliminary stages. Further large, well-designed, randomised controlled trials are necessary to confirm the efficacy of these novel treatments in order to make formal recommendations regarding their use in the management of onychomycosis.

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