Characteristics of Peripapillary Intrachoroidal Cavitation in Highly Myopic Eyes: The ZOC-BHVI High Myopia Cohort Study.

Ran Liu, Zhixi Li, Ou Xiao, M. S. Jian, Xinxing Guo, Jonathan Tak Loong Lee, Decai Wang, Peiying Lee, Monica Jong, Padmaja Sankaridurg, Mingguang He

Research output: Contribution to journalArticle

Abstract

Purpose:
To characterize peripapillary intrachoroidal cavitation (PICC) in highly myopic participants and its associated risk factors.

Methods:
This observational, cross-sectional study recruited 890 Chinese participants with bilateral high myopia, defined as ≤ -6.00 diopters spherical power. Fundus photography and spectral-domain optical coherence tomography were used to determine the presence of PICC, defined as a yellow-orange lesion adjacent to the disc border with a corresponding intrachoroidal hyporeflective space.

Results:
Among 890 participants, 884 right eyes were included for analysis. The rate of PICC was 3.6% (32 eyes). PICC was observed in 2 eyes without myopic retinal lesions, 9 eyes with tessellated fundus only, 16 eyes with diffuse chorioretinal atrophy and 5 eyes with patchy chorioretinal atrophy. The most commonly affected area was inferior disc border (87.5%), followed by multiple (9.4%) and superior (3.1%) disc borders. Multiple linear logistic regression model showed that older age, more myopic spherical equivalent and longer axial length were associated with the presence of PICC.

Conclusions:
Peripapillary intrachoroidal cavitation was present in 3.6% of highly myopic eyes. It was more common in eyes with a higher myopic maculopathy category. Older age, more myopic spherical equivalent and longer axial length were risk factors for the presence of PICC.
Original languageEnglish
Pages (from-to)1-20
Number of pages20
JournalRetina
DOIs
Publication statusE-pub ahead of print - Aug 2020
Externally publishedYes

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