Purpose: The dual concepts of evidence-based practice (EBP) and clinical effectiveness have become ever more important in the health service in recent years. In order that suitable initiatives can be derived and future policy shaped and evaluated it is important that the current level of knowledge and attitudes towards the concepts are recorded. The current study aimed to examine these in a representative sample of radiographers. Methods: A total of 138 individual radiographers selected at random from the population of radiographers within Wales were approached and requested to complete a postal questionnaire. Of those approached, 76 completed and returned the questionnaire. Results: Individuals considered themselves to be lacking in certain key skills essential for evidence-based practice. Specifically, these appeared to be related to the more 'technical' research-related skills and there was limited evidence that individuals were undertaking many of these components. However, attitudes towards EBP and clinical effectiveness were, by and large, positive. Conclusion: The current underlying culture provides a firm foundation for the necessary education and encouragement required for the fuller implementation of evidence based practice in radiographers.