Cocoa and chocolate, their clinical benefits

Insights in study design

Duane D. Mellor, Ekavi N. Georgousopoulou, Nenad Naumovski

    Research output: Contribution to journalReview article

    Abstract

    Randomized controlled trials and meta-analyses have demonstrated the potential protective effect of cocoa and chocolate consumption with respect to cardiovascular disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which include reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate have been assessed for their potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.

    Original languageEnglish
    Pages (from-to)1-7
    Number of pages7
    JournalCAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources
    Volume12
    DOIs
    Publication statusPublished - 2017

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    cocoa
    cardiovascular disease
    chocolate
    experimental design
    cardiovascular diseases
    Cardiovascular Diseases
    experimental study
    stroke
    protective effect
    Meta-Analysis
    mechanism of action
    risk factors
    Randomized Controlled Trials
    Stroke
    Health
    dosage
    consumption
    effect
    Chocolate
    trial

    Cite this

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    abstract = "Randomized controlled trials and meta-analyses have demonstrated the potential protective effect of cocoa and chocolate consumption with respect to cardiovascular disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which include reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate have been assessed for their potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.",
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    Cocoa and chocolate, their clinical benefits : Insights in study design. / Mellor, Duane D.; Georgousopoulou, Ekavi N.; Naumovski, Nenad.

    In: CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, Vol. 12, 2017, p. 1-7.

    Research output: Contribution to journalReview article

    TY - JOUR

    T1 - Cocoa and chocolate, their clinical benefits

    T2 - Insights in study design

    AU - Mellor, Duane D.

    AU - Georgousopoulou, Ekavi N.

    AU - Naumovski, Nenad

    PY - 2017

    Y1 - 2017

    N2 - Randomized controlled trials and meta-analyses have demonstrated the potential protective effect of cocoa and chocolate consumption with respect to cardiovascular disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which include reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate have been assessed for their potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.

    AB - Randomized controlled trials and meta-analyses have demonstrated the potential protective effect of cocoa and chocolate consumption with respect to cardiovascular disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which include reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate have been assessed for their potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.

    KW - Cardiovascular disease

    KW - Chocolate

    KW - Cocoa

    KW - Review

    KW - Risk factors

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    DO - 10.1079/PAVSNNR201712018

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    JF - CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources

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