Comparison of ocular comfort, vision, and SICS during silicone hydrogel contact lens daily wear

Jennie Diec, Victoria E. Evans, Daniel Tilia, Thomas Naduvilath, Brien A. Holden, Percy Lazon De La Jara

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)


Objectives: The aim of this study was to investigate the relationship between solution-induced corneal staining (SICS) and silicone hydrogel contact lens comfort and vision. Methods: A retrospective analysis of a series of open-label studies were conducted with 24 groups of approximately 40 participants, each wearing 1 of 6 silicone hydrogel contact lenses with 1 of 4 lens care products bilaterally for 3 months of daily wear. The presence of SICS and subjective ocular ratings were collected at 2 weeks and at 1 and 3 months. Results: A total of 1,051 participants were enrolled. The participants with SICS rated significantly less favorably than did the participants without SICS for comfort during the day (7.9±1.7 vs. 8.5±1.4, P=0.03), comfort at the end of the day (6.6±2.1 vs. 7.4±1.9, P=0.03), overall dryness (7.4±1.9 vs. 8.0±1.7, P=0.04), dryness at the end of the day (6.7±2.2 vs. 7.5±2.1, P=0.01), feelings of burning and stinging (8.5±2.0 vs. 8.9±1.8, P=0.02), and overall vision (8.2±1.6 vs. 8.7±1.3, P<0.001). Conclusions: The participants with SICS had lower subjective comfort and vision compared with those who did not experience SICS.

Original languageEnglish
Pages (from-to)2-6
Number of pages5
JournalEye and Contact Lens
Issue number1
Publication statusPublished - Jan 2012
Externally publishedYes


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