TY - JOUR
T1 - Comparison of ocular comfort, vision, and SICS during silicone hydrogel contact lens daily wear
AU - Diec, Jennie
AU - Evans, Victoria E.
AU - Tilia, Daniel
AU - Naduvilath, Thomas
AU - Holden, Brien A.
AU - De La Jara, Percy Lazon
PY - 2012/1
Y1 - 2012/1
N2 - Objectives: The aim of this study was to investigate the relationship between solution-induced corneal staining (SICS) and silicone hydrogel contact lens comfort and vision. Methods: A retrospective analysis of a series of open-label studies were conducted with 24 groups of approximately 40 participants, each wearing 1 of 6 silicone hydrogel contact lenses with 1 of 4 lens care products bilaterally for 3 months of daily wear. The presence of SICS and subjective ocular ratings were collected at 2 weeks and at 1 and 3 months. Results: A total of 1,051 participants were enrolled. The participants with SICS rated significantly less favorably than did the participants without SICS for comfort during the day (7.9±1.7 vs. 8.5±1.4, P=0.03), comfort at the end of the day (6.6±2.1 vs. 7.4±1.9, P=0.03), overall dryness (7.4±1.9 vs. 8.0±1.7, P=0.04), dryness at the end of the day (6.7±2.2 vs. 7.5±2.1, P=0.01), feelings of burning and stinging (8.5±2.0 vs. 8.9±1.8, P=0.02), and overall vision (8.2±1.6 vs. 8.7±1.3, P<0.001). Conclusions: The participants with SICS had lower subjective comfort and vision compared with those who did not experience SICS.
AB - Objectives: The aim of this study was to investigate the relationship between solution-induced corneal staining (SICS) and silicone hydrogel contact lens comfort and vision. Methods: A retrospective analysis of a series of open-label studies were conducted with 24 groups of approximately 40 participants, each wearing 1 of 6 silicone hydrogel contact lenses with 1 of 4 lens care products bilaterally for 3 months of daily wear. The presence of SICS and subjective ocular ratings were collected at 2 weeks and at 1 and 3 months. Results: A total of 1,051 participants were enrolled. The participants with SICS rated significantly less favorably than did the participants without SICS for comfort during the day (7.9±1.7 vs. 8.5±1.4, P=0.03), comfort at the end of the day (6.6±2.1 vs. 7.4±1.9, P=0.03), overall dryness (7.4±1.9 vs. 8.0±1.7, P=0.04), dryness at the end of the day (6.7±2.2 vs. 7.5±2.1, P=0.01), feelings of burning and stinging (8.5±2.0 vs. 8.9±1.8, P=0.02), and overall vision (8.2±1.6 vs. 8.7±1.3, P<0.001). Conclusions: The participants with SICS had lower subjective comfort and vision compared with those who did not experience SICS.
KW - Comfort
KW - Silicone hydrogel-Contact lenses
KW - Solution-induced corneal staining
KW - Vision
UR - http://www.scopus.com/inward/record.url?scp=84855358075&partnerID=8YFLogxK
U2 - 10.1097/ICL.0b013e318239df9f
DO - 10.1097/ICL.0b013e318239df9f
M3 - Article
C2 - 22169881
AN - SCOPUS:84855358075
SN - 1542-2321
VL - 38
SP - 2
EP - 6
JO - Eye and Contact Lens
JF - Eye and Contact Lens
IS - 1
ER -