Comparison of the effects on lipoproteins and apolipoproteins of a diet high in monounsaturated fatty acids, enriched with avocado, and a high-carbohydrate diet

David M. Colquhoun, Denise Moores, Shawn M. Somerset, Julie A. Humphries

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

A randomized trial was conducted to compare effects of a diet high in monounsaturated fatty acids, enriched with avocado (AE), and a high-complex-carbohydrate diet (AHA-III) on blood lipid concentrations. Fifteen females between 37 and 58 y of age were allocated either to AE followed by AHA-III, or vice versa. Each dietary phase lasted 3 wk. Both diets were found to lower total cholesterol compared with baseline values. AE was more effective, with an 8.2% decrease (P < 0.05) whereas AHA-III was associated with a 4.9% decrease (NS). Low-density-lipoprotein cholesterol and apolipoprotein B decreased significantly on AE but not on AHA-III (P < 0.05). The high-density-lipoprotein (HDL) concentration did not change on AE but decreased 13.9% on AHA-III (P < 0.01). It is concluded that AE is more effective than is AHA-III in decreasing total cholesterol, and, unlike AHA-III, it does not decrease HDL concentrations.

Original languageEnglish
Pages (from-to)671-677
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume56
Issue number4
DOIs
Publication statusPublished - 1 Jan 1992
Externally publishedYes

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Persea
Monounsaturated Fatty Acids
Apolipoproteins
Lipoproteins
Carbohydrates
HDL Lipoproteins
Diet
Cholesterol
Apolipoproteins B
LDL Cholesterol
Lipids

Cite this

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abstract = "A randomized trial was conducted to compare effects of a diet high in monounsaturated fatty acids, enriched with avocado (AE), and a high-complex-carbohydrate diet (AHA-III) on blood lipid concentrations. Fifteen females between 37 and 58 y of age were allocated either to AE followed by AHA-III, or vice versa. Each dietary phase lasted 3 wk. Both diets were found to lower total cholesterol compared with baseline values. AE was more effective, with an 8.2{\%} decrease (P < 0.05) whereas AHA-III was associated with a 4.9{\%} decrease (NS). Low-density-lipoprotein cholesterol and apolipoprotein B decreased significantly on AE but not on AHA-III (P < 0.05). The high-density-lipoprotein (HDL) concentration did not change on AE but decreased 13.9{\%} on AHA-III (P < 0.01). It is concluded that AE is more effective than is AHA-III in decreasing total cholesterol, and, unlike AHA-III, it does not decrease HDL concentrations.",
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Comparison of the effects on lipoproteins and apolipoproteins of a diet high in monounsaturated fatty acids, enriched with avocado, and a high-carbohydrate diet. / Colquhoun, David M.; Moores, Denise; Somerset, Shawn M.; Humphries, Julie A.

In: American Journal of Clinical Nutrition, Vol. 56, No. 4, 01.01.1992, p. 671-677.

Research output: Contribution to journalArticle

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