Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness, and physical activity in children - the LOOK study

Dick TELFORD; Ross Cunningham; Jonathan Shaw; David Dunstan; Tony Lafferty; Graham Reynolds; Peter Hickman; Emma Southcott; Julia M. Potter; Paul Waring; Rohan Telford

doi:10.1111/j.1399-5448.2009.00513.x

Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness, and physical activity in children - the LOOK study

Dick TELFORD, Ross Cunningham, Jonathan Shaw, David Dunstan, Tony Lafferty, Graham Reynolds, Peter Hickman, Emma Southcott, Julia M. Potter, Paul Waring, Rohan Telford

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness and physical activity in children- the LOOK study.Background: Knowledge of individual changes in insulin resistance (IR) and longitudinal relationships of IR with lifestyle-associated factors are of important practical significance, but little longitudinal data exist in asymptomatic children. We aimed to determine (a) changes in the homeostatic model of insulin resistance (HOMA-IR) over a 2-yr period and (b) comparisons of longitudinal and cross-sectional relationships between HOMA-IR and lifestyle-related risk factors. Methods: Our subjects, 241 boys and 257 girls, were assessed at age 8.1 yr (SD 0.35) and again 2 yr later for fasting blood glucose and insulin, dual X-ray absorptiometry-assessed percentage of body fat (%BF), pedometer-assessed physical activity (PA), and cardio-respiratory fitness (CRF) by multistage running test.

Original language	English
Pages (from-to)	500-507
Number of pages	8
Journal	Pediatric Diabetes
Volume	10
Issue number	8
DOIs	https://doi.org/10.1111/j.1399-5448.2009.00513.x
Publication status	Published - 2009
Externally published	Yes

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TELFORD, D., Cunningham, R., Shaw, J., Dunstan, D., Lafferty, T., Reynolds, G., Hickman, P., Southcott, E., Potter, J. M., Waring, P., & Telford, R. (2009). Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness, and physical activity in children - the LOOK study. Pediatric Diabetes, 10(8), 500-507. https://doi.org/10.1111/j.1399-5448.2009.00513.x

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title = "Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness, and physical activity in children - the LOOK study",

abstract = "Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness and physical activity in children- the LOOK study.Background: Knowledge of individual changes in insulin resistance (IR) and longitudinal relationships of IR with lifestyle-associated factors are of important practical significance, but little longitudinal data exist in asymptomatic children. We aimed to determine (a) changes in the homeostatic model of insulin resistance (HOMA-IR) over a 2-yr period and (b) comparisons of longitudinal and cross-sectional relationships between HOMA-IR and lifestyle-related risk factors. Methods: Our subjects, 241 boys and 257 girls, were assessed at age 8.1 yr (SD 0.35) and again 2 yr later for fasting blood glucose and insulin, dual X-ray absorptiometry-assessed percentage of body fat (%BF), pedometer-assessed physical activity (PA), and cardio-respiratory fitness (CRF) by multistage running test.",

keywords = "Body fat, Children, Fitness, IR, Obesity, PA",

author = "Dick TELFORD and Ross Cunningham and Jonathan Shaw and David Dunstan and Tony Lafferty and Graham Reynolds and Peter Hickman and Emma Southcott and Potter, {Julia M.} and Paul Waring and Rohan Telford",

year = "2009",

doi = "10.1111/j.1399-5448.2009.00513.x",

language = "English",

volume = "10",

pages = "500--507",

journal = "Pediatric Diabetes",

issn = "1399-543X",

publisher = "Blackwell Munksgaard",

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TELFORD, D, Cunningham, R, Shaw, J, Dunstan, D, Lafferty, T, Reynolds, G, Hickman, P, Southcott, E, Potter, JM, Waring, P & Telford, R 2009, 'Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness, and physical activity in children - the LOOK study', Pediatric Diabetes, vol. 10, no. 8, pp. 500-507. https://doi.org/10.1111/j.1399-5448.2009.00513.x

TY - JOUR

T1 - Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness, and physical activity in children - the LOOK study

AU - TELFORD, Dick

AU - Cunningham, Ross

AU - Shaw, Jonathan

AU - Dunstan, David

AU - Lafferty, Tony

AU - Reynolds, Graham

AU - Hickman, Peter

AU - Southcott, Emma

AU - Potter, Julia M.

AU - Waring, Paul

AU - Telford, Rohan

PY - 2009

Y1 - 2009

N2 - Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness and physical activity in children- the LOOK study.Background: Knowledge of individual changes in insulin resistance (IR) and longitudinal relationships of IR with lifestyle-associated factors are of important practical significance, but little longitudinal data exist in asymptomatic children. We aimed to determine (a) changes in the homeostatic model of insulin resistance (HOMA-IR) over a 2-yr period and (b) comparisons of longitudinal and cross-sectional relationships between HOMA-IR and lifestyle-related risk factors. Methods: Our subjects, 241 boys and 257 girls, were assessed at age 8.1 yr (SD 0.35) and again 2 yr later for fasting blood glucose and insulin, dual X-ray absorptiometry-assessed percentage of body fat (%BF), pedometer-assessed physical activity (PA), and cardio-respiratory fitness (CRF) by multistage running test.

AB - Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness and physical activity in children- the LOOK study.Background: Knowledge of individual changes in insulin resistance (IR) and longitudinal relationships of IR with lifestyle-associated factors are of important practical significance, but little longitudinal data exist in asymptomatic children. We aimed to determine (a) changes in the homeostatic model of insulin resistance (HOMA-IR) over a 2-yr period and (b) comparisons of longitudinal and cross-sectional relationships between HOMA-IR and lifestyle-related risk factors. Methods: Our subjects, 241 boys and 257 girls, were assessed at age 8.1 yr (SD 0.35) and again 2 yr later for fasting blood glucose and insulin, dual X-ray absorptiometry-assessed percentage of body fat (%BF), pedometer-assessed physical activity (PA), and cardio-respiratory fitness (CRF) by multistage running test.

KW - Body fat

KW - Children

KW - Fitness

KW - IR

KW - Obesity

KW - PA

U2 - 10.1111/j.1399-5448.2009.00513.x

DO - 10.1111/j.1399-5448.2009.00513.x

M3 - Article

SN - 1399-543X

VL - 10

SP - 500

EP - 507

JO - Pediatric Diabetes

JF - Pediatric Diabetes

IS - 8

ER -

Contrasting longitudinal and cross-sectional relationships between insulin resistance and percentage of body fat, fitness, and physical activity in children - the LOOK study

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