Correlation between light levels and the development of deprivation myopia

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    43 Citations (Scopus)

    Abstract

    Methods: Experiment 1: Chicks wore translucent diffusers monocularly for a period of 7 days, with exposure to one of five light intensities (500, 10,000, 20,000, 30,000, and 40,000 lux, n = 12 per group). Experiment 2: Chickens wore translucent diffusers monocularly for 11 days and were split into three groups: (1) chicks reared under 500 lux, (2) chicks reared under 40,000 lux, and (3) chicks reared under 500 lux for the first 4 days and 40,000 lux for the remaining 7 days.

    Results: A significant correlation was observed between log light intensity and the development of FDM, with a lesser myopic refraction (F (28, 330) = 60.86, P < 0.0001) and shorter axial length (F (4, 20) = 8.87, P < 0.0001) seen with increasing light intensities. The progression of FDM was halted in chicks that were switched from 500 to 40,000 lux.

    Conclusions: The level of protection from the development of FDM increases with increasing light intensity. Daily exposure to 40,000 lux almost completely prevents the onset of FDM and, once myopia is established, halts further progression.

    Purpose: In chicks, daily exposure to bright light (15,000 lux) retards the development of form-deprivation myopia (FDM) by roughly 60%. This study investigated whether higher light intensities increase the amount of protection against FDM, and whether protection and light intensity are correlated. Furthermore, we examined if exposure to bright light can prevent the progression of FDM or whether it affects only the onset of experimental myopia.

    Original languageEnglish
    Pages (from-to)299-309
    Number of pages11
    JournalInvestigative Ophthalmology and Visual Science
    Volume56
    Issue number1
    DOIs
    Publication statusPublished - 2015

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    @article{d96bd1ab3cce48e3a561c1bc8ec31c27,
    title = "Correlation between light levels and the development of deprivation myopia",
    abstract = "Methods: Experiment 1: Chicks wore translucent diffusers monocularly for a period of 7 days, with exposure to one of five light intensities (500, 10,000, 20,000, 30,000, and 40,000 lux, n = 12 per group). Experiment 2: Chickens wore translucent diffusers monocularly for 11 days and were split into three groups: (1) chicks reared under 500 lux, (2) chicks reared under 40,000 lux, and (3) chicks reared under 500 lux for the first 4 days and 40,000 lux for the remaining 7 days.Results: A significant correlation was observed between log light intensity and the development of FDM, with a lesser myopic refraction (F (28, 330) = 60.86, P < 0.0001) and shorter axial length (F (4, 20) = 8.87, P < 0.0001) seen with increasing light intensities. The progression of FDM was halted in chicks that were switched from 500 to 40,000 lux.Conclusions: The level of protection from the development of FDM increases with increasing light intensity. Daily exposure to 40,000 lux almost completely prevents the onset of FDM and, once myopia is established, halts further progression.Purpose: In chicks, daily exposure to bright light (15,000 lux) retards the development of form-deprivation myopia (FDM) by roughly 60{\%}. This study investigated whether higher light intensities increase the amount of protection against FDM, and whether protection and light intensity are correlated. Furthermore, we examined if exposure to bright light can prevent the progression of FDM or whether it affects only the onset of experimental myopia.",
    keywords = "Eye growth, Light intensity, Myopia, Outdoor activity, Visual-Neuroscience, Development, outdoor activity, light intensity, eye growth, myopia",
    author = "Regan ASHBY",
    year = "2015",
    doi = "10.1167/iovs.14-15499",
    language = "English",
    volume = "56",
    pages = "299--309",
    journal = "Investigative Ophthalmology",
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    }

    Correlation between light levels and the development of deprivation myopia. / ASHBY, Regan.

    In: Investigative Ophthalmology and Visual Science, Vol. 56, No. 1, 2015, p. 299-309.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Correlation between light levels and the development of deprivation myopia

    AU - ASHBY, Regan

    PY - 2015

    Y1 - 2015

    N2 - Methods: Experiment 1: Chicks wore translucent diffusers monocularly for a period of 7 days, with exposure to one of five light intensities (500, 10,000, 20,000, 30,000, and 40,000 lux, n = 12 per group). Experiment 2: Chickens wore translucent diffusers monocularly for 11 days and were split into three groups: (1) chicks reared under 500 lux, (2) chicks reared under 40,000 lux, and (3) chicks reared under 500 lux for the first 4 days and 40,000 lux for the remaining 7 days.Results: A significant correlation was observed between log light intensity and the development of FDM, with a lesser myopic refraction (F (28, 330) = 60.86, P < 0.0001) and shorter axial length (F (4, 20) = 8.87, P < 0.0001) seen with increasing light intensities. The progression of FDM was halted in chicks that were switched from 500 to 40,000 lux.Conclusions: The level of protection from the development of FDM increases with increasing light intensity. Daily exposure to 40,000 lux almost completely prevents the onset of FDM and, once myopia is established, halts further progression.Purpose: In chicks, daily exposure to bright light (15,000 lux) retards the development of form-deprivation myopia (FDM) by roughly 60%. This study investigated whether higher light intensities increase the amount of protection against FDM, and whether protection and light intensity are correlated. Furthermore, we examined if exposure to bright light can prevent the progression of FDM or whether it affects only the onset of experimental myopia.

    AB - Methods: Experiment 1: Chicks wore translucent diffusers monocularly for a period of 7 days, with exposure to one of five light intensities (500, 10,000, 20,000, 30,000, and 40,000 lux, n = 12 per group). Experiment 2: Chickens wore translucent diffusers monocularly for 11 days and were split into three groups: (1) chicks reared under 500 lux, (2) chicks reared under 40,000 lux, and (3) chicks reared under 500 lux for the first 4 days and 40,000 lux for the remaining 7 days.Results: A significant correlation was observed between log light intensity and the development of FDM, with a lesser myopic refraction (F (28, 330) = 60.86, P < 0.0001) and shorter axial length (F (4, 20) = 8.87, P < 0.0001) seen with increasing light intensities. The progression of FDM was halted in chicks that were switched from 500 to 40,000 lux.Conclusions: The level of protection from the development of FDM increases with increasing light intensity. Daily exposure to 40,000 lux almost completely prevents the onset of FDM and, once myopia is established, halts further progression.Purpose: In chicks, daily exposure to bright light (15,000 lux) retards the development of form-deprivation myopia (FDM) by roughly 60%. This study investigated whether higher light intensities increase the amount of protection against FDM, and whether protection and light intensity are correlated. Furthermore, we examined if exposure to bright light can prevent the progression of FDM or whether it affects only the onset of experimental myopia.

    KW - Eye growth

    KW - Light intensity

    KW - Myopia

    KW - Outdoor activity

    KW - Visual-Neuroscience

    KW - Development

    KW - outdoor activity

    KW - light intensity

    KW - eye growth

    KW - myopia

    UR - http://www.scopus.com/inward/record.url?scp=84921287394&partnerID=8YFLogxK

    UR - http://www.mendeley.com/research/correlation-between-light-levels-development-deprivation-myopia

    U2 - 10.1167/iovs.14-15499

    DO - 10.1167/iovs.14-15499

    M3 - Article

    VL - 56

    SP - 299

    EP - 309

    JO - Investigative Ophthalmology

    JF - Investigative Ophthalmology

    SN - 0146-0404

    IS - 1

    ER -