Correlation between Quality of Life measures and retinal structure and function in patients with age-related macular degeneration

Faran SABETI, Ted Maddess, Emilie Rohan, Rohan W. Essex, Elinor McKone, Jo Lane

Research output: Contribution to conference (non-published works)Poster

Abstract

Purpose: The purpose of this study was to examine the relationship between quality of life (QoL) measures and visual function in advanced age-related macular degeneration (AMD). Methods: We examined 18 female (82.2 ± 9.0 years, mean ± SD) and 9 males (82.9 ± 6.0 years) patients with exudative AMD from the ophthalmology department at The Canberra Hospital (TCH). Patients visual function was measured with both high contrast and low contrast visual acuity charts that followed standardized format of the Early Treatment Diabetic Retinopathy Study (ETDRS) charts. Visual sensitivity was measured with Matrix 10-2 threshold Frequency doubling technology (FDT) testing. Results: There was no significant association between any visual function measure and quality of life measure; however, a significant negative correlation between central retinal thickness and MacDQol (β=-0.66, p=0.02) and National Eye Institute Visual Functioning Questionnaire 25 (β=-0.63, p=0.04) was found. Conclusions:
These results indicate that central retinal thickness has a stronger association with quality of life measures than visual function. In addition, retinal sensitivity losses became symmetrical with progression in MD.
Original languageEnglish
Pages74-74
Number of pages1
Publication statusPublished - 28 May 2019
EventAssociation for Research in Vision and Ophthalmology 2018 - Honolulu, United States
Duration: 29 Apr 20183 May 2018

Conference

ConferenceAssociation for Research in Vision and Ophthalmology 2018
Abbreviated titleARVO
CountryUnited States
CityHonolulu
Period29/04/183/05/18

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Macular Degeneration
Quality of Life
National Eye Institute (U.S.)
Diabetic Retinopathy
Ophthalmology
Visual Acuity
Technology
Therapeutics

Cite this

SABETI, F., Maddess, T., Rohan, E., Essex, R. W., McKone, E., & Lane, J. (2019). Correlation between Quality of Life measures and retinal structure and function in patients with age-related macular degeneration. 74-74. Poster session presented at Association for Research in Vision and Ophthalmology 2018, Honolulu, United States.
SABETI, Faran ; Maddess, Ted ; Rohan, Emilie ; Essex, Rohan W. ; McKone, Elinor ; Lane, Jo. / Correlation between Quality of Life measures and retinal structure and function in patients with age-related macular degeneration. Poster session presented at Association for Research in Vision and Ophthalmology 2018, Honolulu, United States.1 p.
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SABETI, F, Maddess, T, Rohan, E, Essex, RW, McKone, E & Lane, J 2019, 'Correlation between Quality of Life measures and retinal structure and function in patients with age-related macular degeneration' Association for Research in Vision and Ophthalmology 2018, Honolulu, United States, 29/04/18 - 3/05/18, pp. 74-74.

Correlation between Quality of Life measures and retinal structure and function in patients with age-related macular degeneration. / SABETI, Faran; Maddess, Ted; Rohan, Emilie; Essex, Rohan W.; McKone, Elinor; Lane, Jo.

2019. 74-74 Poster session presented at Association for Research in Vision and Ophthalmology 2018, Honolulu, United States.

Research output: Contribution to conference (non-published works)Poster

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AU - SABETI, Faran

AU - Maddess, Ted

AU - Rohan, Emilie

AU - Essex, Rohan W.

AU - McKone, Elinor

AU - Lane, Jo

PY - 2019/5/28

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N2 - Purpose: The purpose of this study was to examine the relationship between quality of life (QoL) measures and visual function in advanced age-related macular degeneration (AMD). Methods: We examined 18 female (82.2 ± 9.0 years, mean ± SD) and 9 males (82.9 ± 6.0 years) patients with exudative AMD from the ophthalmology department at The Canberra Hospital (TCH). Patients visual function was measured with both high contrast and low contrast visual acuity charts that followed standardized format of the Early Treatment Diabetic Retinopathy Study (ETDRS) charts. Visual sensitivity was measured with Matrix 10-2 threshold Frequency doubling technology (FDT) testing. Results: There was no significant association between any visual function measure and quality of life measure; however, a significant negative correlation between central retinal thickness and MacDQol (β=-0.66, p=0.02) and National Eye Institute Visual Functioning Questionnaire 25 (β=-0.63, p=0.04) was found. Conclusions: These results indicate that central retinal thickness has a stronger association with quality of life measures than visual function. In addition, retinal sensitivity losses became symmetrical with progression in MD.

AB - Purpose: The purpose of this study was to examine the relationship between quality of life (QoL) measures and visual function in advanced age-related macular degeneration (AMD). Methods: We examined 18 female (82.2 ± 9.0 years, mean ± SD) and 9 males (82.9 ± 6.0 years) patients with exudative AMD from the ophthalmology department at The Canberra Hospital (TCH). Patients visual function was measured with both high contrast and low contrast visual acuity charts that followed standardized format of the Early Treatment Diabetic Retinopathy Study (ETDRS) charts. Visual sensitivity was measured with Matrix 10-2 threshold Frequency doubling technology (FDT) testing. Results: There was no significant association between any visual function measure and quality of life measure; however, a significant negative correlation between central retinal thickness and MacDQol (β=-0.66, p=0.02) and National Eye Institute Visual Functioning Questionnaire 25 (β=-0.63, p=0.04) was found. Conclusions: These results indicate that central retinal thickness has a stronger association with quality of life measures than visual function. In addition, retinal sensitivity losses became symmetrical with progression in MD.

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SABETI F, Maddess T, Rohan E, Essex RW, McKone E, Lane J. Correlation between Quality of Life measures and retinal structure and function in patients with age-related macular degeneration. 2019. Poster session presented at Association for Research in Vision and Ophthalmology 2018, Honolulu, United States.