TY - JOUR
T1 - Cross-Sectional Associations of Reallocating Time Between Sedentary and Active Behaviours on Cardiometabolic Risk Factors in Young People
T2 - An International Children’s Accelerometry Database (ICAD) Analysis
AU - the International Children’s Accelerometry Database (ICAD) Collaborators
AU - Hansen, Bjørge Herman
AU - Anderssen, Sigmund Alfred
AU - Andersen, Lars B.
AU - Hildebrand, Maria
AU - Kolle, Elin
AU - Steene-Johannessen, Jostein
AU - Kriemler, Susi
AU - Puder, Jardena J.
AU - Sherar, Lauren B.
AU - Reilly, John J.
AU - Sardinha, Luis B.
AU - van Sluijs, Esther M.F.
AU - Wedderkopp, Niels
AU - Ekelund, Ulf
AU - Riddoch, Chris
AU - Judge, Ken
AU - Griew, Pippa
AU - Andersen, Lars Bo
AU - Anderssen, Sigmund
AU - Atkin, Andrew J.
AU - Cardon, Greet
AU - DAVEY, Rachel
AU - Esliger, Dale
AU - Hallal, Pedro
AU - Janz, Kathleen F.
AU - Kriemler, Susi
AU - Møller, Niels
AU - Northstone, Kate
AU - Pate, Russell
AU - Puder, Jardena
AU - Reilly, John
AU - Salmon, Jo
AU - Sardinha, Luis
AU - Sherar, Lauren
AU - Timperio, Anna
AU - van Sluijs, Esther M.F.
N1 - Funding Information:
Funding and Acknowledgements The authors would like to thank all participants and funders of the original studies who contributed data to the ICAD. Pooling of the data was funded through a grant
Publisher Copyright:
© 2018, The Author(s).
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Introduction: Sedentary time and time spent in various intensity-specific physical activity are co-dependent, and increasing time spent in one behaviour requires decreased time in another. Objective: The aim of the present study was to examine the theoretical associations with reallocating time between categories of intensities and cardiometabolic risk factors in a large and heterogeneous sample of children and adolescents. Methods: We analysed pooled data from 13 studies comprising 18,200 children and adolescents aged 4–18 years from the International Children’s Accelerometry Database (ICAD). Waist-mounted accelerometers measured sedentary time, light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA). Cardiometabolic risk factors included waist circumference (WC), systolic blood pressure (SBP), fasting high- and low-density lipoprotein cholesterol (HDL-C and LDL-C), triglycerides, insulin, and glucose. Associations of reallocating time between the various intensity categories with cardiometabolic risk factors were explored using isotemporal substitution modelling. Results: Replacing 10 min of sedentary time with 10 min of MVPA showed favourable associations with WC, SBP, LDL-C, insulin, triglycerides, and glucose; the greatest magnitude was observed for insulin (reduction of 2–4%), WC (reduction of 0.5–1%), and triglycerides (1–2%). In addition, replacing 10 min of sedentary time with an equal amount of LPA showed beneficial associations with WC, although only in adolescents. Conclusions: Replacing sedentary time and/or LPA with MVPA in children and adolescents is favourably associated with most markers of cardiometabolic risk. Efforts aimed at replacing sedentary time with active behaviours, particularly those of at least moderate intensity, appear to be an effective strategy to reduce cardiometabolic risk in young people.
AB - Introduction: Sedentary time and time spent in various intensity-specific physical activity are co-dependent, and increasing time spent in one behaviour requires decreased time in another. Objective: The aim of the present study was to examine the theoretical associations with reallocating time between categories of intensities and cardiometabolic risk factors in a large and heterogeneous sample of children and adolescents. Methods: We analysed pooled data from 13 studies comprising 18,200 children and adolescents aged 4–18 years from the International Children’s Accelerometry Database (ICAD). Waist-mounted accelerometers measured sedentary time, light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA). Cardiometabolic risk factors included waist circumference (WC), systolic blood pressure (SBP), fasting high- and low-density lipoprotein cholesterol (HDL-C and LDL-C), triglycerides, insulin, and glucose. Associations of reallocating time between the various intensity categories with cardiometabolic risk factors were explored using isotemporal substitution modelling. Results: Replacing 10 min of sedentary time with 10 min of MVPA showed favourable associations with WC, SBP, LDL-C, insulin, triglycerides, and glucose; the greatest magnitude was observed for insulin (reduction of 2–4%), WC (reduction of 0.5–1%), and triglycerides (1–2%). In addition, replacing 10 min of sedentary time with an equal amount of LPA showed beneficial associations with WC, although only in adolescents. Conclusions: Replacing sedentary time and/or LPA with MVPA in children and adolescents is favourably associated with most markers of cardiometabolic risk. Efforts aimed at replacing sedentary time with active behaviours, particularly those of at least moderate intensity, appear to be an effective strategy to reduce cardiometabolic risk in young people.
KW - Accelerometry
KW - Adolescent
KW - Biomarkers/blood
KW - Blood Pressure
KW - Cardiovascular Diseases/prevention & control
KW - Child
KW - Child, Preschool
KW - Cross-Sectional Studies
KW - Exercise
KW - Female
KW - Humans
KW - Male
KW - Risk Factors
KW - Sedentary Behavior
KW - Time Factors
KW - Waist Circumference
UR - http://www.scopus.com/inward/record.url?scp=85045029538&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/crosssectional-associations-reallocating-time-between-sedentary-active-behaviours-cardiometabolic-ri-2
U2 - 10.1007/s40279-018-0909-1
DO - 10.1007/s40279-018-0909-1
M3 - Article
C2 - 29626333
AN - SCOPUS:85045029538
SN - 0112-1642
VL - 48
SP - 2401
EP - 2412
JO - Sports Medicine
JF - Sports Medicine
IS - 10
ER -
