Deaths Due to Screenable Cancers Among People Living With HIV Infection, Florida, 2000-2014

Mary Jo Trepka, Rehab Auf, Kristopher P Fennie, Diana M Sheehan, Lorene M Maddox, Theophile Niyonsenga

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

INTRODUCTION: Because of antiretroviral therapy, people living with HIV infection are surviving longer and are at higher risk for chronic diseases. This study's objective was to assess the magnitude of deaths due to cancers for which there are screening recommendations for people living with HIV in Florida. METHODS: Florida Department of Health Enhanced HIV/AIDS Reporting System data were matched with Department of Health Vital Records and the National Death Index to identify deaths and their causes through 2014. The sex-specific and cause-specific mortality rates and indirect standardized mortality ratios (SMRs, using U.S. mortality rates as a standard) were calculated during 2016 for people reported with HIV infection 2000-2014.

RESULTS: Despite the competing risk of HIV mortality, among the 25,678 females, there was a higher risk of cervical (SMR=6.32, 95% CI=4.63, 8.44), colorectal (SMR=2.05, 95% CI=1.44, 2.83), liver (SMR=8.96, 95% CI=5.39, 14.03), and lung (SMR=5.82, 95% CI=4.80, 6.96) cancer mortality and lower risk of breast cancer mortality (SMR=0.57, 95% CI=0.42, 0.76). Among 63,493 males, there was a higher risk of liver (SMR=5.50, 95% CI=4.47, 6.70) and lung (4.63, 95% CI=4.11, 5.19) cancer mortality. Among males, the lung cancer SMR significantly declined 2000-2014 (p<0.05), but was still high in 2012-2014 (SMR=3.59, 95% CI=2.87, 4.43). CONCLUSIONS: These results indicate the importance of primary and secondary cancer prevention during primary care for people living with HIV infection.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalAmerican Journal of Preventive Medicine
Volume53
Issue number5
Early online date24 Jul 2017
DOIs
Publication statusPublished - Nov 2017
Externally publishedYes

Fingerprint

HIV Infections
Mortality
Neoplasms
HIV
Lung
Death Certificates
Liver
Health
Secondary Prevention
Early Detection of Cancer
Information Systems
Cause of Death
Lung Neoplasms
Primary Health Care
Acquired Immunodeficiency Syndrome
Chronic Disease
Research Design
Breast Neoplasms

Cite this

Trepka, Mary Jo ; Auf, Rehab ; Fennie, Kristopher P ; Sheehan, Diana M ; Maddox, Lorene M ; Niyonsenga, Theophile. / Deaths Due to Screenable Cancers Among People Living With HIV Infection, Florida, 2000-2014. In: American Journal of Preventive Medicine. 2017 ; Vol. 53, No. 5. pp. 1-5.
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abstract = "INTRODUCTION: Because of antiretroviral therapy, people living with HIV infection are surviving longer and are at higher risk for chronic diseases. This study's objective was to assess the magnitude of deaths due to cancers for which there are screening recommendations for people living with HIV in Florida. METHODS: Florida Department of Health Enhanced HIV/AIDS Reporting System data were matched with Department of Health Vital Records and the National Death Index to identify deaths and their causes through 2014. The sex-specific and cause-specific mortality rates and indirect standardized mortality ratios (SMRs, using U.S. mortality rates as a standard) were calculated during 2016 for people reported with HIV infection 2000-2014.RESULTS: Despite the competing risk of HIV mortality, among the 25,678 females, there was a higher risk of cervical (SMR=6.32, 95{\%} CI=4.63, 8.44), colorectal (SMR=2.05, 95{\%} CI=1.44, 2.83), liver (SMR=8.96, 95{\%} CI=5.39, 14.03), and lung (SMR=5.82, 95{\%} CI=4.80, 6.96) cancer mortality and lower risk of breast cancer mortality (SMR=0.57, 95{\%} CI=0.42, 0.76). Among 63,493 males, there was a higher risk of liver (SMR=5.50, 95{\%} CI=4.47, 6.70) and lung (4.63, 95{\%} CI=4.11, 5.19) cancer mortality. Among males, the lung cancer SMR significantly declined 2000-2014 (p<0.05), but was still high in 2012-2014 (SMR=3.59, 95{\%} CI=2.87, 4.43). CONCLUSIONS: These results indicate the importance of primary and secondary cancer prevention during primary care for people living with HIV infection.",
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Deaths Due to Screenable Cancers Among People Living With HIV Infection, Florida, 2000-2014. / Trepka, Mary Jo; Auf, Rehab; Fennie, Kristopher P; Sheehan, Diana M; Maddox, Lorene M; Niyonsenga, Theophile.

In: American Journal of Preventive Medicine, Vol. 53, No. 5, 11.2017, p. 1-5.

Research output: Contribution to journalArticle

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T1 - Deaths Due to Screenable Cancers Among People Living With HIV Infection, Florida, 2000-2014

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AU - Auf, Rehab

AU - Fennie, Kristopher P

AU - Sheehan, Diana M

AU - Maddox, Lorene M

AU - Niyonsenga, Theophile

N1 - Copyright © 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

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N2 - INTRODUCTION: Because of antiretroviral therapy, people living with HIV infection are surviving longer and are at higher risk for chronic diseases. This study's objective was to assess the magnitude of deaths due to cancers for which there are screening recommendations for people living with HIV in Florida. METHODS: Florida Department of Health Enhanced HIV/AIDS Reporting System data were matched with Department of Health Vital Records and the National Death Index to identify deaths and their causes through 2014. The sex-specific and cause-specific mortality rates and indirect standardized mortality ratios (SMRs, using U.S. mortality rates as a standard) were calculated during 2016 for people reported with HIV infection 2000-2014.RESULTS: Despite the competing risk of HIV mortality, among the 25,678 females, there was a higher risk of cervical (SMR=6.32, 95% CI=4.63, 8.44), colorectal (SMR=2.05, 95% CI=1.44, 2.83), liver (SMR=8.96, 95% CI=5.39, 14.03), and lung (SMR=5.82, 95% CI=4.80, 6.96) cancer mortality and lower risk of breast cancer mortality (SMR=0.57, 95% CI=0.42, 0.76). Among 63,493 males, there was a higher risk of liver (SMR=5.50, 95% CI=4.47, 6.70) and lung (4.63, 95% CI=4.11, 5.19) cancer mortality. Among males, the lung cancer SMR significantly declined 2000-2014 (p<0.05), but was still high in 2012-2014 (SMR=3.59, 95% CI=2.87, 4.43). CONCLUSIONS: These results indicate the importance of primary and secondary cancer prevention during primary care for people living with HIV infection.

AB - INTRODUCTION: Because of antiretroviral therapy, people living with HIV infection are surviving longer and are at higher risk for chronic diseases. This study's objective was to assess the magnitude of deaths due to cancers for which there are screening recommendations for people living with HIV in Florida. METHODS: Florida Department of Health Enhanced HIV/AIDS Reporting System data were matched with Department of Health Vital Records and the National Death Index to identify deaths and their causes through 2014. The sex-specific and cause-specific mortality rates and indirect standardized mortality ratios (SMRs, using U.S. mortality rates as a standard) were calculated during 2016 for people reported with HIV infection 2000-2014.RESULTS: Despite the competing risk of HIV mortality, among the 25,678 females, there was a higher risk of cervical (SMR=6.32, 95% CI=4.63, 8.44), colorectal (SMR=2.05, 95% CI=1.44, 2.83), liver (SMR=8.96, 95% CI=5.39, 14.03), and lung (SMR=5.82, 95% CI=4.80, 6.96) cancer mortality and lower risk of breast cancer mortality (SMR=0.57, 95% CI=0.42, 0.76). Among 63,493 males, there was a higher risk of liver (SMR=5.50, 95% CI=4.47, 6.70) and lung (4.63, 95% CI=4.11, 5.19) cancer mortality. Among males, the lung cancer SMR significantly declined 2000-2014 (p<0.05), but was still high in 2012-2014 (SMR=3.59, 95% CI=2.87, 4.43). CONCLUSIONS: These results indicate the importance of primary and secondary cancer prevention during primary care for people living with HIV infection.

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DO - 10.1016/j.amepre.2017.05.018

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JO - American Journal of Preventive Medicine

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