Decomposition of six common selenium species found in animal tissues using microwave digestion with nitric acid and ICP-MS

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    Abstract

    In this paper we report the decomposition of common selenium species (selenocysteine, selenomethionine, trimethylselenonium ion, selenosugar-1, methyl-2-acetamido-2-deoxy-1-seleno-ß- d-glucopyranoside, selenosugar-2, methyl-2-acetamido-2-deoxy-1-seleno-ß- d-galactopyranoside and selenosugar-3, methyl-2-amino-2-deoxy-1-seleno-ß- d-galactopyranoside) expected to be found in animal tissues and urine using microwave digestion with nitric acid and ICP-MS. Complete decomposition of selenocystine to selenious acid was achieved, selenomethionine and the two selenosugars, were partially degraded to selenious acid and methylseleninic acid while trimethylselenonium ion was not degraded at all. Hydride generation techniques that rely on selenium to be in an inorganic form would have underestimated total selenium in extracts given that these species have different reactivities with borohydride. As trimethylselenonium ion is not degraded, this may lead to the formation of volatile dimethyselenide or dimethyldiselenide during hydride generation and an overestimation of selenium concentration.
    Original languageEnglish
    Pages (from-to)92-95
    Number of pages4
    JournalMicrochemical Journal
    Volume126
    DOIs
    Publication statusPublished - 2016

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    Nitric Acid
    Selenium
    Animals
    Microwaves
    Tissue
    Selenomethionine
    Decomposition
    Selenious Acid
    Ions
    Galactose
    Hydrides
    Selenocysteine
    Borohydrides
    trimethylselenonium

    Cite this

    @article{bffdeead815a4804bd9f8a7675f331bc,
    title = "Decomposition of six common selenium species found in animal tissues using microwave digestion with nitric acid and ICP-MS",
    abstract = "In this paper we report the decomposition of common selenium species (selenocysteine, selenomethionine, trimethylselenonium ion, selenosugar-1, methyl-2-acetamido-2-deoxy-1-seleno-{\ss}- d-glucopyranoside, selenosugar-2, methyl-2-acetamido-2-deoxy-1-seleno-{\ss}- d-galactopyranoside and selenosugar-3, methyl-2-amino-2-deoxy-1-seleno-{\ss}- d-galactopyranoside) expected to be found in animal tissues and urine using microwave digestion with nitric acid and ICP-MS. Complete decomposition of selenocystine to selenious acid was achieved, selenomethionine and the two selenosugars, were partially degraded to selenious acid and methylseleninic acid while trimethylselenonium ion was not degraded at all. Hydride generation techniques that rely on selenium to be in an inorganic form would have underestimated total selenium in extracts given that these species have different reactivities with borohydride. As trimethylselenonium ion is not degraded, this may lead to the formation of volatile dimethyselenide or dimethyldiselenide during hydride generation and an overestimation of selenium concentration.",
    author = "Bill MAHER and Simon FOSTER",
    year = "2016",
    doi = "10.1016/j.microc.2015.11.009",
    language = "English",
    volume = "126",
    pages = "92--95",
    journal = "Microchemical Journal",
    issn = "0026-265X",
    publisher = "Elsevier Inc.",

    }

    TY - JOUR

    T1 - Decomposition of six common selenium species found in animal tissues using microwave digestion with nitric acid and ICP-MS

    AU - MAHER, Bill

    AU - FOSTER, Simon

    PY - 2016

    Y1 - 2016

    N2 - In this paper we report the decomposition of common selenium species (selenocysteine, selenomethionine, trimethylselenonium ion, selenosugar-1, methyl-2-acetamido-2-deoxy-1-seleno-ß- d-glucopyranoside, selenosugar-2, methyl-2-acetamido-2-deoxy-1-seleno-ß- d-galactopyranoside and selenosugar-3, methyl-2-amino-2-deoxy-1-seleno-ß- d-galactopyranoside) expected to be found in animal tissues and urine using microwave digestion with nitric acid and ICP-MS. Complete decomposition of selenocystine to selenious acid was achieved, selenomethionine and the two selenosugars, were partially degraded to selenious acid and methylseleninic acid while trimethylselenonium ion was not degraded at all. Hydride generation techniques that rely on selenium to be in an inorganic form would have underestimated total selenium in extracts given that these species have different reactivities with borohydride. As trimethylselenonium ion is not degraded, this may lead to the formation of volatile dimethyselenide or dimethyldiselenide during hydride generation and an overestimation of selenium concentration.

    AB - In this paper we report the decomposition of common selenium species (selenocysteine, selenomethionine, trimethylselenonium ion, selenosugar-1, methyl-2-acetamido-2-deoxy-1-seleno-ß- d-glucopyranoside, selenosugar-2, methyl-2-acetamido-2-deoxy-1-seleno-ß- d-galactopyranoside and selenosugar-3, methyl-2-amino-2-deoxy-1-seleno-ß- d-galactopyranoside) expected to be found in animal tissues and urine using microwave digestion with nitric acid and ICP-MS. Complete decomposition of selenocystine to selenious acid was achieved, selenomethionine and the two selenosugars, were partially degraded to selenious acid and methylseleninic acid while trimethylselenonium ion was not degraded at all. Hydride generation techniques that rely on selenium to be in an inorganic form would have underestimated total selenium in extracts given that these species have different reactivities with borohydride. As trimethylselenonium ion is not degraded, this may lead to the formation of volatile dimethyselenide or dimethyldiselenide during hydride generation and an overestimation of selenium concentration.

    U2 - 10.1016/j.microc.2015.11.009

    DO - 10.1016/j.microc.2015.11.009

    M3 - Article

    VL - 126

    SP - 92

    EP - 95

    JO - Microchemical Journal

    JF - Microchemical Journal

    SN - 0026-265X

    ER -