TY - JOUR
T1 - Dietary anti-inflammatory index, metabolic syndrome and transition in metabolic status; a gender-specific analysis of ATTICA prospective study
AU - ATTICA study Investigators
AU - Kouvari, Matina
AU - Panagiotakos, Demosthenes B
AU - Naumovski, Nenad
AU - Chrysohoou, Christina
AU - Georgousopoulou, Ekavi N
AU - Yannakoulia, Mary
AU - Tousoulis, Dimitrios
AU - Pitsavos, Christos
N1 - Funding Information:
The ATTICA study is supported by research grants from the Hellenic Cardiology Society [ HCS2002 ] and the Hellenic Atherosclerosis Society [ HAS2003 ]. This work was supported by the Ageing Trajectories of Health: Longitudinal Opportunities and Synergies (ATHLOS) project, which has received funding from the European Union’s Horizon 2020 research and innovation programme (No 635316 ). The present work is also supported by a research grant from Hellenic Atherosclerosis Society.
Funding Information:
The authors would like to thank the ATTICA study investigators: Y. Skoumas, N. Katinioti, L. Papadimitriou, C. Masoura, S. Vellas, Y. Lentzas, M. Kambaxis, K. Paliou, V. Metaxa, N. Skourlis, C. Papanikolaou, A. Kalogeropoulou, E. Pitaraki, A. Laskaris, M. Hatzigeorgiou, A. Grekas, E. Kokkou, C. Vassiliadou, G. Dedousis, M. Toutouza-Giotsa, C. Tselika, S. Poulopouloou, M. Toutouza. The authors declare that they have no conflict of interest. The ATTICA study is supported by research grants from the Hellenic Cardiology Society [HCS2002] and the Hellenic Atherosclerosis Society [HAS2003]. This work was supported by the Ageing Trajectories of Health: Longitudinal Opportunities and Synergies (ATHLOS) project, which has received funding from the European Union's Horizon 2020 research and innovation programme (No 635316). The present work is also supported by a research grant from Hellenic Atherosclerosis Society.
Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2020/3
Y1 - 2020/3
N2 - AIMS: To examine the association between dietary anti-inflammatory index (D-AII) and metabolic syndrome (MetS)prevalence, 10-year (2002-2012) diabetes, hypertension, hypercholesterolaemia incidence and 10-year transition from healthy (absence of all MetS traits, excluding waist circumference) to unhealthy metabolic status.METHODS: In 2001-2002, n=1,514 men and n=1,528 women (>18 years old) in Athens, Greece, free of cardiovascular disease were recruited. MetS was defined according to the revised NCEP ATP III (2005) or the IDF criteria or the harmonized criteria. The validated D-AII was calculated using a standardized procedure (range 10-77).RESULTS: Inverse associations were observed between D-AII and transition from healthy to unhealthy metabolic status (Odds Ratio (OR)3rd vs. 1st tertile= 0.88 95% Confidence Interval (95%CI)(0.73, 0.98)) and diabetes (OR3rd vs. 1st tertile= 0.55, 95%CI(0.29, 0.77)). In women, D-AII was inversely associated with transition from healthy to unhealthy metabolic status (OR3rd vs. 1st tertile= 0.55, 95%CI(0.26, 0.90), diabetes (OR3rd vs. 1st tertile= 0.41, 95%CI(0.18, 0.64) and hypertension (OR3rd vs. 1st tertile= 0.75, 95%CI(0.20, 0.95), yet only with diabetes incidence in men (OR3rd vs. 1st tertile= 0.62, 95%CI(0.38, 0.93).CONCLUSIONS: Diet with high anti-inflammatory load seems an effective preventive measure to retain a metabolically benign status, principally in terms of glycemic control.
AB - AIMS: To examine the association between dietary anti-inflammatory index (D-AII) and metabolic syndrome (MetS)prevalence, 10-year (2002-2012) diabetes, hypertension, hypercholesterolaemia incidence and 10-year transition from healthy (absence of all MetS traits, excluding waist circumference) to unhealthy metabolic status.METHODS: In 2001-2002, n=1,514 men and n=1,528 women (>18 years old) in Athens, Greece, free of cardiovascular disease were recruited. MetS was defined according to the revised NCEP ATP III (2005) or the IDF criteria or the harmonized criteria. The validated D-AII was calculated using a standardized procedure (range 10-77).RESULTS: Inverse associations were observed between D-AII and transition from healthy to unhealthy metabolic status (Odds Ratio (OR)3rd vs. 1st tertile= 0.88 95% Confidence Interval (95%CI)(0.73, 0.98)) and diabetes (OR3rd vs. 1st tertile= 0.55, 95%CI(0.29, 0.77)). In women, D-AII was inversely associated with transition from healthy to unhealthy metabolic status (OR3rd vs. 1st tertile= 0.55, 95%CI(0.26, 0.90), diabetes (OR3rd vs. 1st tertile= 0.41, 95%CI(0.18, 0.64) and hypertension (OR3rd vs. 1st tertile= 0.75, 95%CI(0.20, 0.95), yet only with diabetes incidence in men (OR3rd vs. 1st tertile= 0.62, 95%CI(0.38, 0.93).CONCLUSIONS: Diet with high anti-inflammatory load seems an effective preventive measure to retain a metabolically benign status, principally in terms of glycemic control.
KW - Gender
KW - Inflammation
KW - Metabolic syndrome
KW - Nutrition
KW - Primary care
UR - http://www.scopus.com/inward/record.url?scp=85078914089&partnerID=8YFLogxK
U2 - 10.1016/j.diabres.2020.108031
DO - 10.1016/j.diabres.2020.108031
M3 - Review article
C2 - 32004695
SN - 1872-8227
VL - 161
SP - 1
EP - 11
JO - Diabetes Research and Clinical Practice
JF - Diabetes Research and Clinical Practice
M1 - 108031
ER -