Dietary anti-inflammatory index, metabolic syndrome and transition in metabolic status; a gender-specific analysis of ATTICA prospective study

ATTICA study Investigators, Matina Kouvari, Demosthenes B Panagiotakos, Nenad Naumovski, Christina Chrysohoou, Ekavi N Georgousopoulou, Mary Yannakoulia, Dimitrios Tousoulis, Christos Pitsavos

Research output: Contribution to journalReview article

Abstract

AIMS: To examine the association between dietary anti-inflammatory index (D-AII) and metabolic syndrome (MetS)prevalence, 10-year (2002-2012) diabetes, hypertension, hypercholesterolaemia incidence and 10-year transition from healthy (absence of all MetS traits, excluding waist circumference) to unhealthy metabolic status.

METHODS: In 2001-2002, n=1,514 men and n=1,528 women (>18 years old) in Athens, Greece, free of cardiovascular disease were recruited. MetS was defined according to the revised NCEP ATP III (2005) or the IDF criteria or the harmonized criteria. The validated D-AII was calculated using a standardized procedure (range 10-77).

RESULTS: Inverse associations were observed between D-AII and transition from healthy to unhealthy metabolic status (Odds Ratio (OR)3rd vs. 1st tertile= 0.88 95% Confidence Interval (95%CI)(0.73, 0.98)) and diabetes (OR3rd vs. 1st tertile= 0.55, 95%CI(0.29, 0.77)). In women, D-AII was inversely associated with transition from healthy to unhealthy metabolic status (OR3rd vs. 1st tertile= 0.55, 95%CI(0.26, 0.90), diabetes (OR3rd vs. 1st tertile= 0.41, 95%CI(0.18, 0.64) and hypertension (OR3rd vs. 1st tertile= 0.75, 95%CI(0.20, 0.95), yet only with diabetes incidence in men (OR3rd vs. 1st tertile= 0.62, 95%CI(0.38, 0.93).

CONCLUSIONS: Diet with high anti-inflammatory load seems an effective preventive measure to retain a metabolically benign status, principally in terms of glycemic control.

Original languageEnglish
Article number108031
Pages (from-to)1-11
Number of pages11
JournalDiabetes Research and Clinical Practice
Volume161
DOIs
Publication statusPublished - Mar 2020

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Anti-Inflammatory Agents
Prospective Studies
Confidence Intervals
Hypertension
Greece
Incidence
Waist Circumference
Hypercholesterolemia
Cardiovascular Diseases
Adenosine Triphosphate
Odds Ratio
Diet

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ATTICA study Investigators ; Kouvari, Matina ; Panagiotakos, Demosthenes B ; Naumovski, Nenad ; Chrysohoou, Christina ; Georgousopoulou, Ekavi N ; Yannakoulia, Mary ; Tousoulis, Dimitrios ; Pitsavos, Christos. / Dietary anti-inflammatory index, metabolic syndrome and transition in metabolic status; a gender-specific analysis of ATTICA prospective study. In: Diabetes Research and Clinical Practice. 2020 ; Vol. 161. pp. 1-11.
@article{5dfdd09bfd224735b379d28a219543ed,
title = "Dietary anti-inflammatory index, metabolic syndrome and transition in metabolic status; a gender-specific analysis of ATTICA prospective study",
abstract = "AIMS: To examine the association between dietary anti-inflammatory index (D-AII) and metabolic syndrome (MetS)prevalence, 10-year (2002-2012) diabetes, hypertension, hypercholesterolaemia incidence and 10-year transition from healthy (absence of all MetS traits, excluding waist circumference) to unhealthy metabolic status.METHODS: In 2001-2002, n=1,514 men and n=1,528 women (>18 years old) in Athens, Greece, free of cardiovascular disease were recruited. MetS was defined according to the revised NCEP ATP III (2005) or the IDF criteria or the harmonized criteria. The validated D-AII was calculated using a standardized procedure (range 10-77).RESULTS: Inverse associations were observed between D-AII and transition from healthy to unhealthy metabolic status (Odds Ratio (OR)3rd vs. 1st tertile= 0.88 95{\%} Confidence Interval (95{\%}CI)(0.73, 0.98)) and diabetes (OR3rd vs. 1st tertile= 0.55, 95{\%}CI(0.29, 0.77)). In women, D-AII was inversely associated with transition from healthy to unhealthy metabolic status (OR3rd vs. 1st tertile= 0.55, 95{\%}CI(0.26, 0.90), diabetes (OR3rd vs. 1st tertile= 0.41, 95{\%}CI(0.18, 0.64) and hypertension (OR3rd vs. 1st tertile= 0.75, 95{\%}CI(0.20, 0.95), yet only with diabetes incidence in men (OR3rd vs. 1st tertile= 0.62, 95{\%}CI(0.38, 0.93).CONCLUSIONS: Diet with high anti-inflammatory load seems an effective preventive measure to retain a metabolically benign status, principally in terms of glycemic control.",
author = "{ATTICA study Investigators} and Matina Kouvari and Panagiotakos, {Demosthenes B} and Nenad Naumovski and Christina Chrysohoou and Georgousopoulou, {Ekavi N} and Mary Yannakoulia and Dimitrios Tousoulis and Christos Pitsavos",
note = "Copyright {\circledC} 2020. Published by Elsevier B.V.",
year = "2020",
month = "3",
doi = "10.1016/j.diabres.2020.108031",
language = "English",
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ATTICA study Investigators, Kouvari, M, Panagiotakos, DB, Naumovski, N, Chrysohoou, C, Georgousopoulou, EN, Yannakoulia, M, Tousoulis, D & Pitsavos, C 2020, 'Dietary anti-inflammatory index, metabolic syndrome and transition in metabolic status; a gender-specific analysis of ATTICA prospective study', Diabetes Research and Clinical Practice, vol. 161, 108031, pp. 1-11. https://doi.org/10.1016/j.diabres.2020.108031

Dietary anti-inflammatory index, metabolic syndrome and transition in metabolic status; a gender-specific analysis of ATTICA prospective study. / ATTICA study Investigators; Kouvari, Matina; Panagiotakos, Demosthenes B; Naumovski, Nenad; Chrysohoou, Christina; Georgousopoulou, Ekavi N; Yannakoulia, Mary; Tousoulis, Dimitrios; Pitsavos, Christos.

In: Diabetes Research and Clinical Practice, Vol. 161, 108031, 03.2020, p. 1-11.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Dietary anti-inflammatory index, metabolic syndrome and transition in metabolic status; a gender-specific analysis of ATTICA prospective study

AU - ATTICA study Investigators

AU - Kouvari, Matina

AU - Panagiotakos, Demosthenes B

AU - Naumovski, Nenad

AU - Chrysohoou, Christina

AU - Georgousopoulou, Ekavi N

AU - Yannakoulia, Mary

AU - Tousoulis, Dimitrios

AU - Pitsavos, Christos

N1 - Copyright © 2020. Published by Elsevier B.V.

PY - 2020/3

Y1 - 2020/3

N2 - AIMS: To examine the association between dietary anti-inflammatory index (D-AII) and metabolic syndrome (MetS)prevalence, 10-year (2002-2012) diabetes, hypertension, hypercholesterolaemia incidence and 10-year transition from healthy (absence of all MetS traits, excluding waist circumference) to unhealthy metabolic status.METHODS: In 2001-2002, n=1,514 men and n=1,528 women (>18 years old) in Athens, Greece, free of cardiovascular disease were recruited. MetS was defined according to the revised NCEP ATP III (2005) or the IDF criteria or the harmonized criteria. The validated D-AII was calculated using a standardized procedure (range 10-77).RESULTS: Inverse associations were observed between D-AII and transition from healthy to unhealthy metabolic status (Odds Ratio (OR)3rd vs. 1st tertile= 0.88 95% Confidence Interval (95%CI)(0.73, 0.98)) and diabetes (OR3rd vs. 1st tertile= 0.55, 95%CI(0.29, 0.77)). In women, D-AII was inversely associated with transition from healthy to unhealthy metabolic status (OR3rd vs. 1st tertile= 0.55, 95%CI(0.26, 0.90), diabetes (OR3rd vs. 1st tertile= 0.41, 95%CI(0.18, 0.64) and hypertension (OR3rd vs. 1st tertile= 0.75, 95%CI(0.20, 0.95), yet only with diabetes incidence in men (OR3rd vs. 1st tertile= 0.62, 95%CI(0.38, 0.93).CONCLUSIONS: Diet with high anti-inflammatory load seems an effective preventive measure to retain a metabolically benign status, principally in terms of glycemic control.

AB - AIMS: To examine the association between dietary anti-inflammatory index (D-AII) and metabolic syndrome (MetS)prevalence, 10-year (2002-2012) diabetes, hypertension, hypercholesterolaemia incidence and 10-year transition from healthy (absence of all MetS traits, excluding waist circumference) to unhealthy metabolic status.METHODS: In 2001-2002, n=1,514 men and n=1,528 women (>18 years old) in Athens, Greece, free of cardiovascular disease were recruited. MetS was defined according to the revised NCEP ATP III (2005) or the IDF criteria or the harmonized criteria. The validated D-AII was calculated using a standardized procedure (range 10-77).RESULTS: Inverse associations were observed between D-AII and transition from healthy to unhealthy metabolic status (Odds Ratio (OR)3rd vs. 1st tertile= 0.88 95% Confidence Interval (95%CI)(0.73, 0.98)) and diabetes (OR3rd vs. 1st tertile= 0.55, 95%CI(0.29, 0.77)). In women, D-AII was inversely associated with transition from healthy to unhealthy metabolic status (OR3rd vs. 1st tertile= 0.55, 95%CI(0.26, 0.90), diabetes (OR3rd vs. 1st tertile= 0.41, 95%CI(0.18, 0.64) and hypertension (OR3rd vs. 1st tertile= 0.75, 95%CI(0.20, 0.95), yet only with diabetes incidence in men (OR3rd vs. 1st tertile= 0.62, 95%CI(0.38, 0.93).CONCLUSIONS: Diet with high anti-inflammatory load seems an effective preventive measure to retain a metabolically benign status, principally in terms of glycemic control.

U2 - 10.1016/j.diabres.2020.108031

DO - 10.1016/j.diabres.2020.108031

M3 - Review article

VL - 161

SP - 1

EP - 11

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

SN - 0168-8227

M1 - 108031

ER -