Dietary Nitrate improves Cerebral Perfusion, in Young Adults during Exercise: Relationship to Cognitive Performance

Ben Rattray, Lauren Egle-Marshall, Joseph Northey, Simon Hone, Disa Smee, Patrice Brassard

Research output: Contribution to journalMeeting Abstract

1 Citation (Scopus)

Abstract

Dietary nitrate increases middle cerebral artery mean velocity (MCA Vmean) during aerobic exercise but it remains unclear if this is true with the simultaneous inclusion of a cognitively demanding task. Therefore, our aim was to investigate whether nitrate supplementation would influence exercise-induced changes in MCA Vmean, and cognitive performance. In a double blind randomized crossover design, 12 healthy adults consumed two 70 ml doses of either beetroot juice or placebo two hours prior to exercise. Subjects then completed four 8-min workloads of exercise set to elicit 30%, 50%, 70%, and 85% of heart rate reserve (HRR) on a cycle ergometer. Reaction time and accuracy was assessed during a modified version of the color Stroop task, with simple and complex (incongruent) response types, in the last 3 min of each workload. MCA Vmean (Transcranial Doppler) was monitored throughout. MCA Vmean displayed a typical relationship with exercise intensity, but was significantly elevated with beetroot, especially during the complex Stroop task, at 70% (p=0.001, d=0.47) and 85% HRR (p=0.027, d=0.74). Reaction time was not statistically different between conditions regardless of the difficulty level. However, beetroot may have contributed to increased accuracy in the complex task (p=0.059) whilst cycling. These preliminary results suggest that dietary nitrate elevates MCA Vmean during a combined exercise and cognitive challenge, which may be related to improved accuracy during the most demanding tasks.
Original languageEnglish
Article number989.2
Pages (from-to)1-1
Number of pages1
JournalFASEB Journal
Volume29
Issue numberS1
Publication statusPublished - 2015
EventExperimental Biology 2015 - Boston Convention and Exhibition Center, Boston, United States
Duration: 28 Mar 20151 Apr 2015
https://experimentalbiology.org/2019/home.aspx

Cite this

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title = "Dietary Nitrate improves Cerebral Perfusion, in Young Adults during Exercise: Relationship to Cognitive Performance",
abstract = "Dietary nitrate increases middle cerebral artery mean velocity (MCA Vmean) during aerobic exercise but it remains unclear if this is true with the simultaneous inclusion of a cognitively demanding task. Therefore, our aim was to investigate whether nitrate supplementation would influence exercise-induced changes in MCA Vmean, and cognitive performance. In a double blind randomized crossover design, 12 healthy adults consumed two 70 ml doses of either beetroot juice or placebo two hours prior to exercise. Subjects then completed four 8-min workloads of exercise set to elicit 30{\%}, 50{\%}, 70{\%}, and 85{\%} of heart rate reserve (HRR) on a cycle ergometer. Reaction time and accuracy was assessed during a modified version of the color Stroop task, with simple and complex (incongruent) response types, in the last 3 min of each workload. MCA Vmean (Transcranial Doppler) was monitored throughout. MCA Vmean displayed a typical relationship with exercise intensity, but was significantly elevated with beetroot, especially during the complex Stroop task, at 70{\%} (p=0.001, d=0.47) and 85{\%} HRR (p=0.027, d=0.74). Reaction time was not statistically different between conditions regardless of the difficulty level. However, beetroot may have contributed to increased accuracy in the complex task (p=0.059) whilst cycling. These preliminary results suggest that dietary nitrate elevates MCA Vmean during a combined exercise and cognitive challenge, which may be related to improved accuracy during the most demanding tasks.",
author = "Ben Rattray and Lauren Egle-Marshall and Joseph Northey and Simon Hone and Disa Smee and Patrice Brassard",
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Dietary Nitrate improves Cerebral Perfusion, in Young Adults during Exercise: Relationship to Cognitive Performance. / Rattray, Ben; Egle-Marshall, Lauren; Northey, Joseph; Hone, Simon; Smee, Disa; Brassard, Patrice.

In: FASEB Journal, Vol. 29, No. S1, 989.2, 2015, p. 1-1.

Research output: Contribution to journalMeeting Abstract

TY - JOUR

T1 - Dietary Nitrate improves Cerebral Perfusion, in Young Adults during Exercise: Relationship to Cognitive Performance

AU - Rattray, Ben

AU - Egle-Marshall, Lauren

AU - Northey, Joseph

AU - Hone, Simon

AU - Smee, Disa

AU - Brassard, Patrice

PY - 2015

Y1 - 2015

N2 - Dietary nitrate increases middle cerebral artery mean velocity (MCA Vmean) during aerobic exercise but it remains unclear if this is true with the simultaneous inclusion of a cognitively demanding task. Therefore, our aim was to investigate whether nitrate supplementation would influence exercise-induced changes in MCA Vmean, and cognitive performance. In a double blind randomized crossover design, 12 healthy adults consumed two 70 ml doses of either beetroot juice or placebo two hours prior to exercise. Subjects then completed four 8-min workloads of exercise set to elicit 30%, 50%, 70%, and 85% of heart rate reserve (HRR) on a cycle ergometer. Reaction time and accuracy was assessed during a modified version of the color Stroop task, with simple and complex (incongruent) response types, in the last 3 min of each workload. MCA Vmean (Transcranial Doppler) was monitored throughout. MCA Vmean displayed a typical relationship with exercise intensity, but was significantly elevated with beetroot, especially during the complex Stroop task, at 70% (p=0.001, d=0.47) and 85% HRR (p=0.027, d=0.74). Reaction time was not statistically different between conditions regardless of the difficulty level. However, beetroot may have contributed to increased accuracy in the complex task (p=0.059) whilst cycling. These preliminary results suggest that dietary nitrate elevates MCA Vmean during a combined exercise and cognitive challenge, which may be related to improved accuracy during the most demanding tasks.

AB - Dietary nitrate increases middle cerebral artery mean velocity (MCA Vmean) during aerobic exercise but it remains unclear if this is true with the simultaneous inclusion of a cognitively demanding task. Therefore, our aim was to investigate whether nitrate supplementation would influence exercise-induced changes in MCA Vmean, and cognitive performance. In a double blind randomized crossover design, 12 healthy adults consumed two 70 ml doses of either beetroot juice or placebo two hours prior to exercise. Subjects then completed four 8-min workloads of exercise set to elicit 30%, 50%, 70%, and 85% of heart rate reserve (HRR) on a cycle ergometer. Reaction time and accuracy was assessed during a modified version of the color Stroop task, with simple and complex (incongruent) response types, in the last 3 min of each workload. MCA Vmean (Transcranial Doppler) was monitored throughout. MCA Vmean displayed a typical relationship with exercise intensity, but was significantly elevated with beetroot, especially during the complex Stroop task, at 70% (p=0.001, d=0.47) and 85% HRR (p=0.027, d=0.74). Reaction time was not statistically different between conditions regardless of the difficulty level. However, beetroot may have contributed to increased accuracy in the complex task (p=0.059) whilst cycling. These preliminary results suggest that dietary nitrate elevates MCA Vmean during a combined exercise and cognitive challenge, which may be related to improved accuracy during the most demanding tasks.

M3 - Meeting Abstract

VL - 29

SP - 1

EP - 1

JO - FASEB Journal

JF - FASEB Journal

SN - 0892-6638

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