@article{38d6d89fa50c4a938beb84ad3090c656,
title = "Do physical activity and sedentary time mediate the association of the perceived environment with BMI? The IPEN adult study",
abstract = "The study's main aim was to examine whether adults' accelerometer-based physical activity and sedentary time mediated the associations of neighbourhood physical environmental perceptions with body mass index (BMI) and weight status across 10 high- and middle-income countries. Data from the IPEN Adult study, an observational multi-country study (n = 5712) were used. Results showed that sedentary time was a non-significant or inconsistent mediator in all models. MVPA mediated the associations of street connectivity, land use mix-diversity, infrastructure/safety for walking and aesthetics with BMI in single models. In the multiple model, MVPA only fully mediated the relation between land use mix-diversity and BMI. This finding was replicated in the models with weight status as outcome. MVPA partially mediated associations of composite environmental variables with weight status. So, although MVPA mediated some associations, future comprehensive studies are needed to determine other mechanisms that could explain the relation between the physical environment and weight outcomes. Food intake, food accessibility and the home environment may be important variables to consider. Based on the consistency of results across study sites, global advocacy for policies supporting more walkable neighbourhoods should seek to optimize land-use-mix when designing and re-designing cities or towns.",
keywords = "Adults, Community health, Exercise, Physical activity",
author = "{Van Dyck}, Delfien and Ester Cerin and Muhammad Akram and Conway, {Terry L.} and Duncan Macfarlane and Rachel Davey and Sarmiento, {Olga L.} and Christiansen, {Lars Breum} and Rodrigo Reis and Josef Mitas and Ines Aguinaga-Ontoso and Deborah Salvo and Sallis, {James F.}",
note = "Funding Information: Dr James Sallis is the principal investigator on the IPEN coordinating grant funded by the National Institutes of Health, National Cancer Institute. Ethics Committee approval for the lead grant was obtained from Dr Sallis' institution, the University of California, San Diego, Institutional Review Board (Biomedical Committee) and San Diego State University. Additionally, as a requirement for participation in the IPEN study, all 10 countries providing data obtained approval from the Ethics Committee at each principal investigator's home institution.All authors declare financial support for the submitted work from the National Cancer Institute of the National Institutes of Health. US data collection and Coordinating Center processing was supported by the following NIH grants: R01 HL67350 (NHLBI) and R01 CA127296 (NCI). The study conducted in Bogot{\'a} was funded by Colciencias grant 519_2010, Fogarty and CeiBA. The Danish study was partly funded by the Municipality of Aarhus. Data collection in the Czech Republic was supported by the grant MEYS (# MSM 6198959221). Data collected for the UK was in part funded by the Medical Research Council (NPRI Initiative), grant number: 75376. Data collection in Hong Kong was supported by the HK Research Grants Council GRF grants (#HKU740907H and #747807H) and HKU URC Strategic Research Theme (Public Health). Data collection in Mexico was supported by the CDC Foundation which received a training grant from The Coca-Cola Company. James F Sallis received grants and personal fees from the Robert Wood Johnson Foundation outside of submitted work, grants and non-financial support from Nick, Inc. outside of submitted work, is a Santech, Inc. shareholder and is a consultant and receiver of royalties from SPARK Programs of School Specialty, Inc. Ester Cerin is supported by an Australian Research Council Future Fellowship (FT3 #140100085). The funding bodies had no input in study design and the collection, analysis and interpretation of data and the writing of the article and the decision to submit it for publication. All authors are independent from the funding bodies. At time of manuscript preparation, Deborah Salvo was supported by Washington University in St. Louis CDTR (Grant Number P30DK092950 from the NIDDK). The content is solely the responsibility of the authors and does not necessarily represent the official views of the CDTR or NIDDK. Funding Information: Dr James Sallis is the principal investigator on the IPEN coordinating grant funded by the National Institutes of Health , National Cancer Institute . Ethics Committee approval for the lead grant was obtained from Dr Sallis' institution, the University of California, San Diego , Institutional Review Board (Biomedical Committee) and San Diego State University . Additionally, as a requirement for participation in the IPEN study, all 10 countries providing data obtained approval from the Ethics Committee at each principal investigator's home institution. Funding Information: All authors declare financial support for the submitted work from the National Cancer Institute of the National Institutes of Health . US data collection and Coordinating Center processing was supported by the following NIH grants: R01 HL67350 ( NHLBI ) and R01 CA127296 ( NCI ). The study conducted in Bogot{\'a} was funded by Colciencias grant 519_2010 , Fogarty and CeiBA . The Danish study was partly funded by the Municipality of Aarhus . Data collection in the Czech Republic was supported by the grant MEYS ( # MSM 6198959221 ). Data collected for the UK was in part funded by the Medical Research Council (NPRI Initiative), grant number: 75376 . Data collection in Hong Kong was supported by the HK Research Grants Council GRF grants ( #HKU740907H and #747807H ) and HKU URC Strategic Research Theme (Public Health). Data collection in Mexico was supported by the CDC Foundation which received a training grant from The Coca-Cola Company. James F Sallis received grants and personal fees from the Robert Wood Johnson Foundation outside of submitted work, grants and non-financial support from Nick, Inc. outside of submitted work, is a Santech, Inc. shareholder and is a consultant and receiver of royalties from SPARK Programs of School Specialty, Inc. Ester Cerin is supported by an Australian Research Council Future Fellowship ( FT3 #140100085 ). The funding bodies had no input in study design and the collection, analysis and interpretation of data and the writing of the article and the decision to submit it for publication. All authors are independent from the funding bodies. At time of manuscript preparation, Deborah Salvo was supported by Washington University in St. Louis CDTR (Grant Number P30DK092950 from the NIDDK ). The content is solely the responsibility of the authors and does not necessarily represent the official views of the CDTR or NIDDK. Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",
year = "2020",
month = jul,
doi = "10.1016/j.healthplace.2020.102366",
language = "English",
volume = "64",
pages = "1--10",
journal = "Health and Place",
issn = "1353-8292",
publisher = "Elsevier Limited",
}
