Effect of different protocols of caffeine intake on metabolism and endurance performance

Gregory Cox, Ben Desbrow, Megan Anderson, Clinton Bruce, Theodore Macrides, Angela Moquin, John Hawley, Louise Burke

Research output: Contribution to journalArticle

185 Citations (Scopus)

Abstract

Competitive athletes completed two studies of 2-h steady-state (SS) cycling at 70% peak O2uptake followed by 7 kJ/kg time trial (TT) with carbohydrate (CHO) intake before (2 g/kg) and during (6% CHO drink) exercise. In Study A, 12 subjects received either 6 mg/kg caffeine 1 h preexercise (Precaf), 6 × 1 mg/kg caffeine every 20 min throughout SS (Durcaf), 2 × 5 ml/kg Coca-Cola between 100 and 120 min SS and during TT (Coke), or placebo. Improvements in TT were as follows: Precaf, 3.4% (0.2–6.5%, 95% confidence interval); Durcaf, 3.1% (−0.1–6.5%); and Coke, 3.1% (−0.2–6.2%). In Study B, eight subjects received 3 × 5 ml/kg of different cola drinks during the last 40 min of SS and TT: decaffeinated, 6% CHO (control); caffeinated, 6% CHO; decaffeinated, 11% CHO; and caffeinated, 11% CHO (Coke). Coke enhanced TT by 3.3% (0.8–5.9%), with all trials showing 2.2% TT enhancement (0.5–3.8%; P < 0.05) due to caffeine. Overall,1) 6 mg/kg caffeine enhanced TT performance independent of timing of intake and 2) replacing sports drink with Coca-Cola during the latter stages of exercise was equally effective in enhancing endurance performance, primarily due to low intake of caffeine (∼1.5 mg/kg).
Original languageEnglish
Pages (from-to)990-999
Number of pages10
JournalJournal of Applied Physiology
Volume93
Issue number3
DOIs
Publication statusPublished - 2002

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Caffeine
Coke
Exercise
Athletes
Sports
Placebos
Carbohydrates
Confidence Intervals

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Cox, G., Desbrow, B., Anderson, M., Bruce, C., Macrides, T., Moquin, A., ... Burke, L. (2002). Effect of different protocols of caffeine intake on metabolism and endurance performance. Journal of Applied Physiology, 93(3), 990-999. https://doi.org/10.1152/japplphysiol.00249.2002
Cox, Gregory ; Desbrow, Ben ; Anderson, Megan ; Bruce, Clinton ; Macrides, Theodore ; Moquin, Angela ; Hawley, John ; Burke, Louise. / Effect of different protocols of caffeine intake on metabolism and endurance performance. In: Journal of Applied Physiology. 2002 ; Vol. 93, No. 3. pp. 990-999.
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title = "Effect of different protocols of caffeine intake on metabolism and endurance performance",
abstract = "Competitive athletes completed two studies of 2-h steady-state (SS) cycling at 70{\%} peak O2uptake followed by 7 kJ/kg time trial (TT) with carbohydrate (CHO) intake before (2 g/kg) and during (6{\%} CHO drink) exercise. In Study A, 12 subjects received either 6 mg/kg caffeine 1 h preexercise (Precaf), 6 × 1 mg/kg caffeine every 20 min throughout SS (Durcaf), 2 × 5 ml/kg Coca-Cola between 100 and 120 min SS and during TT (Coke), or placebo. Improvements in TT were as follows: Precaf, 3.4{\%} (0.2–6.5{\%}, 95{\%} confidence interval); Durcaf, 3.1{\%} (−0.1–6.5{\%}); and Coke, 3.1{\%} (−0.2–6.2{\%}). In Study B, eight subjects received 3 × 5 ml/kg of different cola drinks during the last 40 min of SS and TT: decaffeinated, 6{\%} CHO (control); caffeinated, 6{\%} CHO; decaffeinated, 11{\%} CHO; and caffeinated, 11{\%} CHO (Coke). Coke enhanced TT by 3.3{\%} (0.8–5.9{\%}), with all trials showing 2.2{\%} TT enhancement (0.5–3.8{\%}; P < 0.05) due to caffeine. Overall,1) 6 mg/kg caffeine enhanced TT performance independent of timing of intake and 2) replacing sports drink with Coca-Cola during the latter stages of exercise was equally effective in enhancing endurance performance, primarily due to low intake of caffeine (∼1.5 mg/kg).",
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Cox, G, Desbrow, B, Anderson, M, Bruce, C, Macrides, T, Moquin, A, Hawley, J & Burke, L 2002, 'Effect of different protocols of caffeine intake on metabolism and endurance performance', Journal of Applied Physiology, vol. 93, no. 3, pp. 990-999. https://doi.org/10.1152/japplphysiol.00249.2002

Effect of different protocols of caffeine intake on metabolism and endurance performance. / Cox, Gregory; Desbrow, Ben; Anderson, Megan; Bruce, Clinton; Macrides, Theodore; Moquin, Angela; Hawley, John; Burke, Louise.

In: Journal of Applied Physiology, Vol. 93, No. 3, 2002, p. 990-999.

Research output: Contribution to journalArticle

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T1 - Effect of different protocols of caffeine intake on metabolism and endurance performance

AU - Cox, Gregory

AU - Desbrow, Ben

AU - Anderson, Megan

AU - Bruce, Clinton

AU - Macrides, Theodore

AU - Moquin, Angela

AU - Hawley, John

AU - Burke, Louise

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AB - Competitive athletes completed two studies of 2-h steady-state (SS) cycling at 70% peak O2uptake followed by 7 kJ/kg time trial (TT) with carbohydrate (CHO) intake before (2 g/kg) and during (6% CHO drink) exercise. In Study A, 12 subjects received either 6 mg/kg caffeine 1 h preexercise (Precaf), 6 × 1 mg/kg caffeine every 20 min throughout SS (Durcaf), 2 × 5 ml/kg Coca-Cola between 100 and 120 min SS and during TT (Coke), or placebo. Improvements in TT were as follows: Precaf, 3.4% (0.2–6.5%, 95% confidence interval); Durcaf, 3.1% (−0.1–6.5%); and Coke, 3.1% (−0.2–6.2%). In Study B, eight subjects received 3 × 5 ml/kg of different cola drinks during the last 40 min of SS and TT: decaffeinated, 6% CHO (control); caffeinated, 6% CHO; decaffeinated, 11% CHO; and caffeinated, 11% CHO (Coke). Coke enhanced TT by 3.3% (0.8–5.9%), with all trials showing 2.2% TT enhancement (0.5–3.8%; P < 0.05) due to caffeine. Overall,1) 6 mg/kg caffeine enhanced TT performance independent of timing of intake and 2) replacing sports drink with Coca-Cola during the latter stages of exercise was equally effective in enhancing endurance performance, primarily due to low intake of caffeine (∼1.5 mg/kg).

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DO - 10.1152/japplphysiol.00249.2002

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JF - Journal of Applied Physiology Respiratory Environmental and Exercise Physiology

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