Effect of stigma reduction intervention strategies on HIV test uptake in low- and middle-income countries

A realist review protocol

Subash Thapa, Karin Hannes, Margaret CARGO, Anne Buve, Catharina Mathei

Research output: Contribution to journalArticle

7 Citations (Scopus)
1 Downloads (Pure)

Abstract

Background: Several stigma reduction intervention strategies have been developed and tested for effectiveness in terms of increasing human immunodeficiency virus (HIV) test uptake. These strategies have been more effective in some contexts and less effective in others. Individual factors, such as lack of knowledge and fear of disclosure, and social-contextual factors, such as poverty and illiteracy, might influence the effect of stigma reduction intervention strategies on HIV test uptake in low- and middle-income countries. So far, it is not clearly known how the stigma reduction intervention strategies interact with these contextual factors to increase HIV test uptake. Therefore, we will conduct a review that will synthesize existing studies on stigma reduction intervention strategies to increase HIV test uptake to better understand the mechanisms underlying this process in low- and middle-income countries. Methods: A realist review will be conducted to unpack context-mechanism-outcome configurations of the effect of stigma reduction intervention strategies on HIV test uptake. Based on a scoping review, we developed a preliminary theoretical framework outlining a potential mechanism of how the intervention strategies influence HIV test uptake. Our realist synthesis will be used to refine the preliminary theoretical framework to better reflect mechanisms that are supported by existing evidence. Journal articles and grey literature will be searched following a purposeful sampling strategy. Data will be extracted and tested against the preliminary theoretical framework. Data synthesis and analysis will be performed in five steps: organizing extracted data into evidence tables, theming, formulating chains of inference from the identified themes, linking the chains of inference and developing generative mechanisms, and refining the framework. Discussion: This will be the first realist review that offers both a quantitative and a qualitative exploration of the available evidence to develop and propose a theoretical framework that explains why and how HIV stigma reduction intervention strategies influence HIV test uptake in low- and middle-income countries. Our theoretical framework is meant to provide guidance to program managers on identifying the most effective stigma reduction intervention strategies to increase HIV test uptake. We also include advice on how to effectively implement these strategies to reduce the rate of HIV transmission. Systematic review registration: PROSPERO CRD42015023687

Original languageEnglish
Article number142
Pages (from-to)1-7
Number of pages7
JournalSystematic Reviews
Volume4
Issue number1
DOIs
Publication statusPublished - 2 Nov 2015
Externally publishedYes

Fingerprint

HIV
Literature
Disclosure
Poverty
Fear

Cite this

@article{5eaa7a8eb65f4bd68f7c067d9618a21a,
title = "Effect of stigma reduction intervention strategies on HIV test uptake in low- and middle-income countries: A realist review protocol",
abstract = "Background: Several stigma reduction intervention strategies have been developed and tested for effectiveness in terms of increasing human immunodeficiency virus (HIV) test uptake. These strategies have been more effective in some contexts and less effective in others. Individual factors, such as lack of knowledge and fear of disclosure, and social-contextual factors, such as poverty and illiteracy, might influence the effect of stigma reduction intervention strategies on HIV test uptake in low- and middle-income countries. So far, it is not clearly known how the stigma reduction intervention strategies interact with these contextual factors to increase HIV test uptake. Therefore, we will conduct a review that will synthesize existing studies on stigma reduction intervention strategies to increase HIV test uptake to better understand the mechanisms underlying this process in low- and middle-income countries. Methods: A realist review will be conducted to unpack context-mechanism-outcome configurations of the effect of stigma reduction intervention strategies on HIV test uptake. Based on a scoping review, we developed a preliminary theoretical framework outlining a potential mechanism of how the intervention strategies influence HIV test uptake. Our realist synthesis will be used to refine the preliminary theoretical framework to better reflect mechanisms that are supported by existing evidence. Journal articles and grey literature will be searched following a purposeful sampling strategy. Data will be extracted and tested against the preliminary theoretical framework. Data synthesis and analysis will be performed in five steps: organizing extracted data into evidence tables, theming, formulating chains of inference from the identified themes, linking the chains of inference and developing generative mechanisms, and refining the framework. Discussion: This will be the first realist review that offers both a quantitative and a qualitative exploration of the available evidence to develop and propose a theoretical framework that explains why and how HIV stigma reduction intervention strategies influence HIV test uptake in low- and middle-income countries. Our theoretical framework is meant to provide guidance to program managers on identifying the most effective stigma reduction intervention strategies to increase HIV test uptake. We also include advice on how to effectively implement these strategies to reduce the rate of HIV transmission. Systematic review registration: PROSPERO CRD42015023687",
keywords = "HIV stigma, HIV test uptake, Low- and middle-income countries, Realist synthesis, Stigma reduction intervention strategies, Humans, Health Knowledge, Attitudes, Practice, HIV Infections/diagnosis, Social Discrimination, Patient Acceptance of Health Care, Systematic Reviews as Topic, Developing Countries, Social Stigma, Research Design",
author = "Subash Thapa and Karin Hannes and Margaret CARGO and Anne Buve and Catharina Mathei",
year = "2015",
month = "11",
day = "2",
doi = "10.1186/s13643-015-0130-3",
language = "English",
volume = "4",
pages = "1--7",
journal = "Systematic Reviews",
issn = "2046-4053",
publisher = "BioMed Central",
number = "1",

}

Effect of stigma reduction intervention strategies on HIV test uptake in low- and middle-income countries : A realist review protocol. / Thapa, Subash; Hannes, Karin; CARGO, Margaret; Buve, Anne; Mathei, Catharina.

In: Systematic Reviews, Vol. 4, No. 1, 142, 02.11.2015, p. 1-7.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effect of stigma reduction intervention strategies on HIV test uptake in low- and middle-income countries

T2 - A realist review protocol

AU - Thapa, Subash

AU - Hannes, Karin

AU - CARGO, Margaret

AU - Buve, Anne

AU - Mathei, Catharina

PY - 2015/11/2

Y1 - 2015/11/2

N2 - Background: Several stigma reduction intervention strategies have been developed and tested for effectiveness in terms of increasing human immunodeficiency virus (HIV) test uptake. These strategies have been more effective in some contexts and less effective in others. Individual factors, such as lack of knowledge and fear of disclosure, and social-contextual factors, such as poverty and illiteracy, might influence the effect of stigma reduction intervention strategies on HIV test uptake in low- and middle-income countries. So far, it is not clearly known how the stigma reduction intervention strategies interact with these contextual factors to increase HIV test uptake. Therefore, we will conduct a review that will synthesize existing studies on stigma reduction intervention strategies to increase HIV test uptake to better understand the mechanisms underlying this process in low- and middle-income countries. Methods: A realist review will be conducted to unpack context-mechanism-outcome configurations of the effect of stigma reduction intervention strategies on HIV test uptake. Based on a scoping review, we developed a preliminary theoretical framework outlining a potential mechanism of how the intervention strategies influence HIV test uptake. Our realist synthesis will be used to refine the preliminary theoretical framework to better reflect mechanisms that are supported by existing evidence. Journal articles and grey literature will be searched following a purposeful sampling strategy. Data will be extracted and tested against the preliminary theoretical framework. Data synthesis and analysis will be performed in five steps: organizing extracted data into evidence tables, theming, formulating chains of inference from the identified themes, linking the chains of inference and developing generative mechanisms, and refining the framework. Discussion: This will be the first realist review that offers both a quantitative and a qualitative exploration of the available evidence to develop and propose a theoretical framework that explains why and how HIV stigma reduction intervention strategies influence HIV test uptake in low- and middle-income countries. Our theoretical framework is meant to provide guidance to program managers on identifying the most effective stigma reduction intervention strategies to increase HIV test uptake. We also include advice on how to effectively implement these strategies to reduce the rate of HIV transmission. Systematic review registration: PROSPERO CRD42015023687

AB - Background: Several stigma reduction intervention strategies have been developed and tested for effectiveness in terms of increasing human immunodeficiency virus (HIV) test uptake. These strategies have been more effective in some contexts and less effective in others. Individual factors, such as lack of knowledge and fear of disclosure, and social-contextual factors, such as poverty and illiteracy, might influence the effect of stigma reduction intervention strategies on HIV test uptake in low- and middle-income countries. So far, it is not clearly known how the stigma reduction intervention strategies interact with these contextual factors to increase HIV test uptake. Therefore, we will conduct a review that will synthesize existing studies on stigma reduction intervention strategies to increase HIV test uptake to better understand the mechanisms underlying this process in low- and middle-income countries. Methods: A realist review will be conducted to unpack context-mechanism-outcome configurations of the effect of stigma reduction intervention strategies on HIV test uptake. Based on a scoping review, we developed a preliminary theoretical framework outlining a potential mechanism of how the intervention strategies influence HIV test uptake. Our realist synthesis will be used to refine the preliminary theoretical framework to better reflect mechanisms that are supported by existing evidence. Journal articles and grey literature will be searched following a purposeful sampling strategy. Data will be extracted and tested against the preliminary theoretical framework. Data synthesis and analysis will be performed in five steps: organizing extracted data into evidence tables, theming, formulating chains of inference from the identified themes, linking the chains of inference and developing generative mechanisms, and refining the framework. Discussion: This will be the first realist review that offers both a quantitative and a qualitative exploration of the available evidence to develop and propose a theoretical framework that explains why and how HIV stigma reduction intervention strategies influence HIV test uptake in low- and middle-income countries. Our theoretical framework is meant to provide guidance to program managers on identifying the most effective stigma reduction intervention strategies to increase HIV test uptake. We also include advice on how to effectively implement these strategies to reduce the rate of HIV transmission. Systematic review registration: PROSPERO CRD42015023687

KW - HIV stigma

KW - HIV test uptake

KW - Low- and middle-income countries

KW - Realist synthesis

KW - Stigma reduction intervention strategies

KW - Humans

KW - Health Knowledge, Attitudes, Practice

KW - HIV Infections/diagnosis

KW - Social Discrimination

KW - Patient Acceptance of Health Care

KW - Systematic Reviews as Topic

KW - Developing Countries

KW - Social Stigma

KW - Research Design

UR - http://www.scopus.com/inward/record.url?scp=84945915681&partnerID=8YFLogxK

UR - http://www.mendeley.com/research/effect-stigma-reduction-intervention-strategies-hiv-test-uptake-low-middleincome-countries-realist-r-1

UR - http://www.mendeley.com/research/effect-stigma-reduction-intervention-strategies-hiv-test-uptake-low-middleincome-countries-realist-r

U2 - 10.1186/s13643-015-0130-3

DO - 10.1186/s13643-015-0130-3

M3 - Article

VL - 4

SP - 1

EP - 7

JO - Systematic Reviews

JF - Systematic Reviews

SN - 2046-4053

IS - 1

M1 - 142

ER -