Effects of lead-spiked sediments on freshwater bivalve, Hyridella australis: linking organism metal exposure-dose-response

Chamani Marasinghe Wadige, Anne TAYLOR, Bill MAHER

    Research output: Contribution to journalArticle

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    Abstract

    Lead entering aquatic ecosystems adsorbs to sediments and has the potential to cause adverse effects on the health of benthic organisms. To evaluate the freshwater bivalve Hyridella australis as a bioindicator for sediment toxicity, their exposure-dose and response to lead contaminated sediments (<0.01, 205 ± 9 and 419 ± 16 g/g dry mass) was investigated in laboratory microcosms using 28 day exposures. Despite high concentrations of lead in the sediments, organisms accumulated low concentrations of lead in their tissues after 28 days of exposure (low treatment: 2.2 ± 0.2 g/g dry mass, high treatment: 4.2 ± 0.1 g/g dry mass), however, accumulated lead concentrations in lead exposed organisms were two fold (low treatment) and four fold (high treatment) higher than that of unexposed organisms (1.2 ± 0.3 g/g dry mass).Accumulation of lead by H. australis may have occurred as analogues of calcium and magnesium. Labial palps accumulated significantly more lead than other tissues. Of the lead accumulated in the hepatopancreas, 83%–91% was detoxified and stored in metal rich granules. The proportions and concentrations of lead in this fraction increased with lead exposure, which suggests that lead detoxification pathway plays an important role in metal tolerance of H. australis. The biologically active lead was mainly present in the mitochondrial fraction which increased with lead exposure. Total antioxidant capacity of H. australis significantly decreased while lipid peroxidation and lysosomal membrane destabilation increased with lead exposure. This study showed a clear lead exposure-dose-response relationship and indicates that H.australis would be a good biomonitor for lead in freshwater ecosystems.
    Original languageEnglish
    Pages (from-to)83-93
    Number of pages11
    JournalAcquayic Toxicology
    Volume149
    DOIs
    Publication statusPublished - 2014

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    Bivalvia
    Fresh Water
    dose response
    bivalve
    Metals
    metals
    sediments
    metal
    organisms
    sediment
    Lead
    organism
    exposure
    effect
    dose
    Ecosystem
    Hepatopancreas
    fold
    metal tolerance
    Environmental Monitoring

    Cite this

    @article{9b8c920cdab44034986eac13d608c113,
    title = "Effects of lead-spiked sediments on freshwater bivalve, Hyridella australis: linking organism metal exposure-dose-response",
    abstract = "Lead entering aquatic ecosystems adsorbs to sediments and has the potential to cause adverse effects on the health of benthic organisms. To evaluate the freshwater bivalve Hyridella australis as a bioindicator for sediment toxicity, their exposure-dose and response to lead contaminated sediments (<0.01, 205 ± 9 and 419 ± 16 g/g dry mass) was investigated in laboratory microcosms using 28 day exposures. Despite high concentrations of lead in the sediments, organisms accumulated low concentrations of lead in their tissues after 28 days of exposure (low treatment: 2.2 ± 0.2 g/g dry mass, high treatment: 4.2 ± 0.1 g/g dry mass), however, accumulated lead concentrations in lead exposed organisms were two fold (low treatment) and four fold (high treatment) higher than that of unexposed organisms (1.2 ± 0.3 g/g dry mass).Accumulation of lead by H. australis may have occurred as analogues of calcium and magnesium. Labial palps accumulated significantly more lead than other tissues. Of the lead accumulated in the hepatopancreas, 83{\%}–91{\%} was detoxified and stored in metal rich granules. The proportions and concentrations of lead in this fraction increased with lead exposure, which suggests that lead detoxification pathway plays an important role in metal tolerance of H. australis. The biologically active lead was mainly present in the mitochondrial fraction which increased with lead exposure. Total antioxidant capacity of H. australis significantly decreased while lipid peroxidation and lysosomal membrane destabilation increased with lead exposure. This study showed a clear lead exposure-dose-response relationship and indicates that H.australis would be a good biomonitor for lead in freshwater ecosystems.",
    keywords = "Biologically active lead, Biologically detoxified lead, Biomarkers, Hyridella australis, Oxidative stress, Sub-cellular partitioning",
    author = "{Marasinghe Wadige}, Chamani and Anne TAYLOR and Bill MAHER",
    year = "2014",
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    language = "English",
    volume = "149",
    pages = "83--93",
    journal = "Acquayic Toxicology",
    issn = "0166-445X",
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    }

    Effects of lead-spiked sediments on freshwater bivalve, Hyridella australis: linking organism metal exposure-dose-response. / Marasinghe Wadige, Chamani; TAYLOR, Anne; MAHER, Bill.

    In: Acquayic Toxicology, Vol. 149, 2014, p. 83-93.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Effects of lead-spiked sediments on freshwater bivalve, Hyridella australis: linking organism metal exposure-dose-response

    AU - Marasinghe Wadige, Chamani

    AU - TAYLOR, Anne

    AU - MAHER, Bill

    PY - 2014

    Y1 - 2014

    N2 - Lead entering aquatic ecosystems adsorbs to sediments and has the potential to cause adverse effects on the health of benthic organisms. To evaluate the freshwater bivalve Hyridella australis as a bioindicator for sediment toxicity, their exposure-dose and response to lead contaminated sediments (<0.01, 205 ± 9 and 419 ± 16 g/g dry mass) was investigated in laboratory microcosms using 28 day exposures. Despite high concentrations of lead in the sediments, organisms accumulated low concentrations of lead in their tissues after 28 days of exposure (low treatment: 2.2 ± 0.2 g/g dry mass, high treatment: 4.2 ± 0.1 g/g dry mass), however, accumulated lead concentrations in lead exposed organisms were two fold (low treatment) and four fold (high treatment) higher than that of unexposed organisms (1.2 ± 0.3 g/g dry mass).Accumulation of lead by H. australis may have occurred as analogues of calcium and magnesium. Labial palps accumulated significantly more lead than other tissues. Of the lead accumulated in the hepatopancreas, 83%–91% was detoxified and stored in metal rich granules. The proportions and concentrations of lead in this fraction increased with lead exposure, which suggests that lead detoxification pathway plays an important role in metal tolerance of H. australis. The biologically active lead was mainly present in the mitochondrial fraction which increased with lead exposure. Total antioxidant capacity of H. australis significantly decreased while lipid peroxidation and lysosomal membrane destabilation increased with lead exposure. This study showed a clear lead exposure-dose-response relationship and indicates that H.australis would be a good biomonitor for lead in freshwater ecosystems.

    AB - Lead entering aquatic ecosystems adsorbs to sediments and has the potential to cause adverse effects on the health of benthic organisms. To evaluate the freshwater bivalve Hyridella australis as a bioindicator for sediment toxicity, their exposure-dose and response to lead contaminated sediments (<0.01, 205 ± 9 and 419 ± 16 g/g dry mass) was investigated in laboratory microcosms using 28 day exposures. Despite high concentrations of lead in the sediments, organisms accumulated low concentrations of lead in their tissues after 28 days of exposure (low treatment: 2.2 ± 0.2 g/g dry mass, high treatment: 4.2 ± 0.1 g/g dry mass), however, accumulated lead concentrations in lead exposed organisms were two fold (low treatment) and four fold (high treatment) higher than that of unexposed organisms (1.2 ± 0.3 g/g dry mass).Accumulation of lead by H. australis may have occurred as analogues of calcium and magnesium. Labial palps accumulated significantly more lead than other tissues. Of the lead accumulated in the hepatopancreas, 83%–91% was detoxified and stored in metal rich granules. The proportions and concentrations of lead in this fraction increased with lead exposure, which suggests that lead detoxification pathway plays an important role in metal tolerance of H. australis. The biologically active lead was mainly present in the mitochondrial fraction which increased with lead exposure. Total antioxidant capacity of H. australis significantly decreased while lipid peroxidation and lysosomal membrane destabilation increased with lead exposure. This study showed a clear lead exposure-dose-response relationship and indicates that H.australis would be a good biomonitor for lead in freshwater ecosystems.

    KW - Biologically active lead

    KW - Biologically detoxified lead

    KW - Biomarkers

    KW - Hyridella australis

    KW - Oxidative stress

    KW - Sub-cellular partitioning

    U2 - 10.1016/j.aquatox.2014.01.017

    DO - 10.1016/j.aquatox.2014.01.017

    M3 - Article

    VL - 149

    SP - 83

    EP - 93

    JO - Acquayic Toxicology

    JF - Acquayic Toxicology

    SN - 0166-445X

    ER -