TY - JOUR
T1 - Electrophysical agents
T2 - from bench to bedside and back again
AU - Chipchase, Lucy
PY - 2010/8/1
Y1 - 2010/8/1
N2 - ‘Bench to bedside’ describes translational research involving a pathway from basic science research to clinical application. Initially used in pharmaceutical development, discoveries in the basic sciences were tested by ‘proof of concept’ studies before large scale clinical trials were conducted.1 The final step involved assessing effectiveness through health service research. However, this model has been criticised for resulting in limited clinical outcomes due to a lack of common purpose and communication between basic scientists at one end of the pipeline and patients and clinicians at the other.
AB - ‘Bench to bedside’ describes translational research involving a pathway from basic science research to clinical application. Initially used in pharmaceutical development, discoveries in the basic sciences were tested by ‘proof of concept’ studies before large scale clinical trials were conducted.1 The final step involved assessing effectiveness through health service research. However, this model has been criticised for resulting in limited clinical outcomes due to a lack of common purpose and communication between basic scientists at one end of the pipeline and patients and clinicians at the other.
UR - http://www.scopus.com/inward/record.url?scp=85044190581&partnerID=8YFLogxK
U2 - 10.1179/174328810X12786297204990
DO - 10.1179/174328810X12786297204990
M3 - Editorial
AN - SCOPUS:85044190581
SN - 1083-3196
VL - 15
SP - 241
EP - 242
JO - Physical Therapy Reviews
JF - Physical Therapy Reviews
IS - 4
ER -