Enhanced Laboratory Diagnosis of Human Chlamydia Pneumoniae Infection through Patter Recognition Derived from Pathology Database Analysis

Alice Richardson, Simon Hawkins, Fariba Shadabi, Dharmendra Sharma, John Fulcher, Brett Lidbury

Research output: A Conference proceeding or a Chapter in BookConference contribution

Abstract

This study focuses on pattern recognition in pathology data collected from patients tested for Chlamydia pneumoniae (Cp) infection, with co-infection by Mycoplasma pneumoniae (Myco) also considered. Both Cp and Myco are microbes that cause respiratory disease in some infected people. As well as the immunoassay results revealing whether the patient had been infected, or not, an extensive range of other routine pathology data was also available for each patient, allowing the analysis of associations between a positive immunoassay laboratory result for Cp or Myco, and a range of tests for biochemical and cellular markers (e.g. liver enzymes, electrolyte balance, haematological indices such as red/white cell counts). Decision trees and logistic regression were used to enhance laboratory diagnosis of these respiratory infections via the formulation of association rules derived from immunoassay results and associated pathology data.
Original languageEnglish
Title of host publicationSupplementary Proceedings of the Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008)
EditorsMadhu Chetty, Shandar Ahmad, Alioune Ngom, Shyh Wei Teng
Place of PublicationAustralia
PublisherThird IAPR International Conference on Pattern Recognition in Bioinformatics
Pages227-234
Number of pages8
ISBN (Print)978073262268
Publication statusPublished - 2008
EventPRIB 2008 - Melbourne, Australia
Duration: 15 Oct 200817 Oct 2008

Conference

ConferencePRIB 2008
CountryAustralia
CityMelbourne
Period15/10/0817/10/08

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Chlamydophila pneumoniae
Mycoplasma pneumoniae
Chlamydia Infections
Clinical Laboratory Techniques
Immunoassay
Databases
Pathology
Decision Trees
Water-Electrolyte Balance
Coinfection
Respiratory Tract Infections
Cell Count
Biomarkers
Logistic Models
Liver
Enzymes

Cite this

Richardson, A., Hawkins, S., Shadabi, F., Sharma, D., Fulcher, J., & Lidbury, B. (2008). Enhanced Laboratory Diagnosis of Human Chlamydia Pneumoniae Infection through Patter Recognition Derived from Pathology Database Analysis. In M. Chetty, S. Ahmad, A. Ngom, & S. W. Teng (Eds.), Supplementary Proceedings of the Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008) (pp. 227-234). Australia: Third IAPR International Conference on Pattern Recognition in Bioinformatics.
Richardson, Alice ; Hawkins, Simon ; Shadabi, Fariba ; Sharma, Dharmendra ; Fulcher, John ; Lidbury, Brett. / Enhanced Laboratory Diagnosis of Human Chlamydia Pneumoniae Infection through Patter Recognition Derived from Pathology Database Analysis. Supplementary Proceedings of the Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008). editor / Madhu Chetty ; Shandar Ahmad ; Alioune Ngom ; Shyh Wei Teng. Australia : Third IAPR International Conference on Pattern Recognition in Bioinformatics, 2008. pp. 227-234
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title = "Enhanced Laboratory Diagnosis of Human Chlamydia Pneumoniae Infection through Patter Recognition Derived from Pathology Database Analysis",
abstract = "This study focuses on pattern recognition in pathology data collected from patients tested for Chlamydia pneumoniae (Cp) infection, with co-infection by Mycoplasma pneumoniae (Myco) also considered. Both Cp and Myco are microbes that cause respiratory disease in some infected people. As well as the immunoassay results revealing whether the patient had been infected, or not, an extensive range of other routine pathology data was also available for each patient, allowing the analysis of associations between a positive immunoassay laboratory result for Cp or Myco, and a range of tests for biochemical and cellular markers (e.g. liver enzymes, electrolyte balance, haematological indices such as red/white cell counts). Decision trees and logistic regression were used to enhance laboratory diagnosis of these respiratory infections via the formulation of association rules derived from immunoassay results and associated pathology data.",
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pages = "227--234",
editor = "Madhu Chetty and Shandar Ahmad and Alioune Ngom and Teng, {Shyh Wei}",
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Richardson, A, Hawkins, S, Shadabi, F, Sharma, D, Fulcher, J & Lidbury, B 2008, Enhanced Laboratory Diagnosis of Human Chlamydia Pneumoniae Infection through Patter Recognition Derived from Pathology Database Analysis. in M Chetty, S Ahmad, A Ngom & SW Teng (eds), Supplementary Proceedings of the Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008). Third IAPR International Conference on Pattern Recognition in Bioinformatics, Australia, pp. 227-234, PRIB 2008, Melbourne, Australia, 15/10/08.

Enhanced Laboratory Diagnosis of Human Chlamydia Pneumoniae Infection through Patter Recognition Derived from Pathology Database Analysis. / Richardson, Alice; Hawkins, Simon; Shadabi, Fariba; Sharma, Dharmendra; Fulcher, John; Lidbury, Brett.

Supplementary Proceedings of the Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008). ed. / Madhu Chetty; Shandar Ahmad; Alioune Ngom; Shyh Wei Teng. Australia : Third IAPR International Conference on Pattern Recognition in Bioinformatics, 2008. p. 227-234.

Research output: A Conference proceeding or a Chapter in BookConference contribution

TY - GEN

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AB - This study focuses on pattern recognition in pathology data collected from patients tested for Chlamydia pneumoniae (Cp) infection, with co-infection by Mycoplasma pneumoniae (Myco) also considered. Both Cp and Myco are microbes that cause respiratory disease in some infected people. As well as the immunoassay results revealing whether the patient had been infected, or not, an extensive range of other routine pathology data was also available for each patient, allowing the analysis of associations between a positive immunoassay laboratory result for Cp or Myco, and a range of tests for biochemical and cellular markers (e.g. liver enzymes, electrolyte balance, haematological indices such as red/white cell counts). Decision trees and logistic regression were used to enhance laboratory diagnosis of these respiratory infections via the formulation of association rules derived from immunoassay results and associated pathology data.

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BT - Supplementary Proceedings of the Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008)

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Richardson A, Hawkins S, Shadabi F, Sharma D, Fulcher J, Lidbury B. Enhanced Laboratory Diagnosis of Human Chlamydia Pneumoniae Infection through Patter Recognition Derived from Pathology Database Analysis. In Chetty M, Ahmad S, Ngom A, Teng SW, editors, Supplementary Proceedings of the Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB 2008). Australia: Third IAPR International Conference on Pattern Recognition in Bioinformatics. 2008. p. 227-234