Exercise, Training, And The Immune System

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Change in the proportion and functional activity of immune cells with exercise and training is reviewed in this article. A schema is proposed to categorize the initial event responsible for the exercise-induced mobilization and activation of leukocytes as either mechanical or metabolic. Irrespective of the initiating event, the phenomenon of a biphasic leukocytosis after exercise, and its hormonal regulation, has been well characterized. Despite some conflicting evidence, it appears that moderate exercise may cause a modest and transient enhancement of immunity, whereas intensive exercise may suppress it. Whether these changes are of biologic significance is yet to be determined. Interpretation of these studies is complicated by large variability in experimental design and treatment. With current knowledge, the physician and coach can implement several strategies for the prevention and management of illness in the elite athlete.

Original languageEnglish
Pages (from-to)47-64
Number of pages18
JournalSports Medicine, Training and Rehabilitation
Volume5
Issue number1
DOIs
Publication statusPublished - 1 Feb 1994
Externally publishedYes

Fingerprint

Immune System
Exercise
Leukocytosis
Athletes
Immunity
Leukocytes
Research Design
Physicians
Therapeutics

Cite this

@article{0f00da45d3c24d2fb1d760aa22ebb5a7,
title = "Exercise, Training, And The Immune System",
abstract = "Change in the proportion and functional activity of immune cells with exercise and training is reviewed in this article. A schema is proposed to categorize the initial event responsible for the exercise-induced mobilization and activation of leukocytes as either mechanical or metabolic. Irrespective of the initiating event, the phenomenon of a biphasic leukocytosis after exercise, and its hormonal regulation, has been well characterized. Despite some conflicting evidence, it appears that moderate exercise may cause a modest and transient enhancement of immunity, whereas intensive exercise may suppress it. Whether these changes are of biologic significance is yet to be determined. Interpretation of these studies is complicated by large variability in experimental design and treatment. With current knowledge, the physician and coach can implement several strategies for the prevention and management of illness in the elite athlete.",
keywords = "exercise, immune system, leukocytosis, stress, training",
author = "Pyne, {David B.}",
year = "1994",
month = "2",
day = "1",
doi = "10.1080/15438629409512001",
language = "English",
volume = "5",
pages = "47--64",
journal = "Sports Medicine, Training and Rehabilitation",
issn = "1543-8627",
publisher = "Taylor and Francis Ltd.",
number = "1",

}

Exercise, Training, And The Immune System. / Pyne, David B.

In: Sports Medicine, Training and Rehabilitation, Vol. 5, No. 1, 01.02.1994, p. 47-64.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Exercise, Training, And The Immune System

AU - Pyne, David B.

PY - 1994/2/1

Y1 - 1994/2/1

N2 - Change in the proportion and functional activity of immune cells with exercise and training is reviewed in this article. A schema is proposed to categorize the initial event responsible for the exercise-induced mobilization and activation of leukocytes as either mechanical or metabolic. Irrespective of the initiating event, the phenomenon of a biphasic leukocytosis after exercise, and its hormonal regulation, has been well characterized. Despite some conflicting evidence, it appears that moderate exercise may cause a modest and transient enhancement of immunity, whereas intensive exercise may suppress it. Whether these changes are of biologic significance is yet to be determined. Interpretation of these studies is complicated by large variability in experimental design and treatment. With current knowledge, the physician and coach can implement several strategies for the prevention and management of illness in the elite athlete.

AB - Change in the proportion and functional activity of immune cells with exercise and training is reviewed in this article. A schema is proposed to categorize the initial event responsible for the exercise-induced mobilization and activation of leukocytes as either mechanical or metabolic. Irrespective of the initiating event, the phenomenon of a biphasic leukocytosis after exercise, and its hormonal regulation, has been well characterized. Despite some conflicting evidence, it appears that moderate exercise may cause a modest and transient enhancement of immunity, whereas intensive exercise may suppress it. Whether these changes are of biologic significance is yet to be determined. Interpretation of these studies is complicated by large variability in experimental design and treatment. With current knowledge, the physician and coach can implement several strategies for the prevention and management of illness in the elite athlete.

KW - exercise

KW - immune system

KW - leukocytosis

KW - stress

KW - training

UR - http://www.scopus.com/inward/record.url?scp=0028350593&partnerID=8YFLogxK

U2 - 10.1080/15438629409512001

DO - 10.1080/15438629409512001

M3 - Article

VL - 5

SP - 47

EP - 64

JO - Sports Medicine, Training and Rehabilitation

JF - Sports Medicine, Training and Rehabilitation

SN - 1543-8627

IS - 1

ER -