TY - JOUR
T1 - Fat metabolism and acute resistance exercise in trained women
AU - Allman, Brittany R.
AU - Morrissey, Margaret C.
AU - Kim, Jeong Su
AU - Panton, Lynn B.
AU - Contreras, Robert J.
AU - Hickner, Robert C.
AU - Ormsbee, Michael J.
N1 - Funding Information:
This research was supported by funds from the Florida State University College of Human Sciences, the Florida State University Graduate School, Dymatize Nutrition Sport Performance Institute, and FreislandCampina.
Publisher Copyright:
© 2019 the American Physiological Society
PY - 2018/9/29
Y1 - 2018/9/29
N2 - This study investigated the effect of acute full-body resistance exercise [RE; one set of 10 repetitions at 40% 1 repetition maximum (1RM) and three sets of 10 repetitions at 65% 1RM] on subcutaneous abdominal adipose tissue (SCAAT) lipolysis and whole body substrate oxidation in young (age: 22 1 yr), normal-weight and body fatness (body mass index: 20 1 kg/m2; %body fat: 28.7 1.4%), resistance-trained women. Microdialysis was used to measure SCAAT lipolysis at baseline, mid-RE, post-RE, and 30 min post-RE, and indirect calorimetry was used to measure whole body substrate oxidation at baseline and immediately post-RE in 13 women. Plasma concentrations of glucose, insulin, nonesterified fatty acids (NEFA), glycerol, growth hormone (GH), epinephrine (Epi), and norepinephrine (NE) were measured at baseline, mid-RE, and post-RE. Lipolysis (dialysate glycerol concentration) was elevated post-RE (baseline: 596.7 82.8, post-RE: 961.4 116.3 M, P 0.01). Energy expenditure (baseline: 1,560 49; post-RE: 1,756 68 kcal/day; P 0.02) and fat oxidation (baseline: 5.64 0.24; post-RE: 7.57 0.41 g/h; P 0.0003) were elevated post-RE. GH (baseline: 513.1 147.4; mid-RE: 1,288.3 83.9; post-RE: 1,522.8 51.1 pg/ml, P 0.000), Epi (baseline: 23.2 2.7; mid-RE: 92.5 16.6; post-RE: 84.5 21.4 pg/ml, P 0.000), and NE (baseline: 139.2 13.6; mid-RE: 850.9 155.3; post-RE: 695.3 93.5 pg/ml, P 0.000) were higher at mid-RE and post-RE. Therefore, one of the potential mechanisms behind RE-induced fat mass changes in resistance-trained women may be in part due to the accumulated effect of transient increases in SCAAT lipolysis, fat oxidation, and energy expenditure, mediated by GH, Epi, and NE release.
AB - This study investigated the effect of acute full-body resistance exercise [RE; one set of 10 repetitions at 40% 1 repetition maximum (1RM) and three sets of 10 repetitions at 65% 1RM] on subcutaneous abdominal adipose tissue (SCAAT) lipolysis and whole body substrate oxidation in young (age: 22 1 yr), normal-weight and body fatness (body mass index: 20 1 kg/m2; %body fat: 28.7 1.4%), resistance-trained women. Microdialysis was used to measure SCAAT lipolysis at baseline, mid-RE, post-RE, and 30 min post-RE, and indirect calorimetry was used to measure whole body substrate oxidation at baseline and immediately post-RE in 13 women. Plasma concentrations of glucose, insulin, nonesterified fatty acids (NEFA), glycerol, growth hormone (GH), epinephrine (Epi), and norepinephrine (NE) were measured at baseline, mid-RE, and post-RE. Lipolysis (dialysate glycerol concentration) was elevated post-RE (baseline: 596.7 82.8, post-RE: 961.4 116.3 M, P 0.01). Energy expenditure (baseline: 1,560 49; post-RE: 1,756 68 kcal/day; P 0.02) and fat oxidation (baseline: 5.64 0.24; post-RE: 7.57 0.41 g/h; P 0.0003) were elevated post-RE. GH (baseline: 513.1 147.4; mid-RE: 1,288.3 83.9; post-RE: 1,522.8 51.1 pg/ml, P 0.000), Epi (baseline: 23.2 2.7; mid-RE: 92.5 16.6; post-RE: 84.5 21.4 pg/ml, P 0.000), and NE (baseline: 139.2 13.6; mid-RE: 850.9 155.3; post-RE: 695.3 93.5 pg/ml, P 0.000) were higher at mid-RE and post-RE. Therefore, one of the potential mechanisms behind RE-induced fat mass changes in resistance-trained women may be in part due to the accumulated effect of transient increases in SCAAT lipolysis, fat oxidation, and energy expenditure, mediated by GH, Epi, and NE release.
KW - Fat oxidation
KW - Growth hormone
KW - Lipolysis
KW - Resistance exercise
KW - Resting metabolic rate
UR - http://www.scopus.com/inward/record.url?scp=85063634708&partnerID=8YFLogxK
U2 - 10.1152/japplphysiol.00752.2018
DO - 10.1152/japplphysiol.00752.2018
M3 - Article
C2 - 30605402
AN - SCOPUS:85063634708
SN - 8750-7587
VL - 126
SP - 739
EP - 745
JO - Journal of Applied Physiology
JF - Journal of Applied Physiology
IS - 3
ER -